Aminalon® [Gamma Aminobutyric Acid]
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Gamma-aminobutyric acid (GABA, gamma-aminobutyric acid) is a biogenic amine, restores metabolic processes in the brain, promotes the utilization of glucose by the brain and the removal of toxic metabolic products from it, and provides normalization of the dynamics of nerve processes in the brain. Increases the productivity of thinking, improves memory, has a mild psychostimulating effect, a positive effect on the restoration of movements and speech after a violation of cerebral circulation. It helps to reduce and stabilize increased blood pressure and reduce the subjective symptoms of arterial hypertension (dizziness, sleep disturbance).
It has a moderate antihypoxic and anticonvulsant action. In patients with diabetes, reduces the glucose content, with normal glucose in the blood has the opposite effect (due to glycogenolysis).
Absorption is fast, fairly complete. Cmax in the blood plasma is reached after 60 minutes, then the concentration rapidly decreases. After 24 hours, GABA is not detected in the blood plasma.
Conditions after cerebral circulatory disorders; after traumatic brain injury. Atherosclerosis of cerebral vessels with symptoms of softening of the brain. Alcohol encephalopathy and polyneuritis. Headache, dizziness, sleep disorders in arterial hypertension. Cerebral palsy; effects of traumatic brain and birth injury in children; mental retardation in children; kinetozy.
|gamma aminobutyric acid||250 mg|
Gamma Aminobutyric Acid is marketed under different brands and generic names, and comes in different dosage forms:
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Dosage and Administration
The daily dose for adults is 3-3.75 g. For children aged 1 to 3 years old, 1-2 g / day; from 4 to 6 years old - 2-3 g / day; older than 7 years - 3 g / day. The daily dose for children and adults is divided into 3 doses and taken before meals. The course of treatment lasts from 2-3 weeks to 2-4 months.
For the prevention and treatment of adult kinetoz - 500 mg 3 times / day for 3-4 days, for children - 250 mg 3 times / day for 3-4 days.
Possible: nausea, vomiting, blood pressure lability, dyspepsia, fever, sleep disturbance.
Hypersensitivity to GABA.
With simultaneous use may enhance the action of benzodiazepine derivatives, many hypnotics and antiepileptic drugs.
In the first days of treatment, fluctuations in blood pressure are possible.
- Brand name: Aminalon
- Active ingredient: Gamma Aminobutyric Acid
- Manufacturer: Organics
- Embryonic and postnatal expression of four gamma-aminobutyric acid transporter mRNAs in the mouse brain and leptomeninges
- Post-embedding immunogold labeling of gamma-aminobutyric acid in lamina II of the spinal trigeminal subnucleus pars caudalis: I. A qualitative study
- Allosteric modulation by single enantiomers of a C3-chiral 1,4-benzodiazepine of the gamma aminobutyric acid type A receptor channel expressed in Xenopus oocytes
- Rostral ventrolateral medulla suppresses reflex bradycardia by the release of gamma-aminobutyric acid in nucleus tractus solitarii of the rat
- Inhibitory actions of the gamma-aminobutyric acid in pediatric Sturge-Weber syndrome
- Idiopathic recurring stupor: A case with possible involvement of the gamma–aminobutyric acid (GABA)ergic system
- The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy
- Immunocytochemical localization of tyrosine hydroxylase and gamma-aminobutyric acid in the mesencephalic trigeminal nucleus of the cat: A light and electron microscopic study
- A highly specific and sensitive determination of gamma-aminobutyric acid by gas chromatography mass spectrometry
- Pattern of expression of engrailed in relation to gamma-aminobutyric acid immunoreactivity in the central nervous system of the adult grasshopper
- Gamma-aminobutyric acid (GABA)-mediated neural connections in the Drosophila antennal lobe
- Neurons and glia in cat superior colliculus accumulate [3H] gamma-aminobutyric acid (GABA)
- Gamma-aminobutyric acid- and glutamic acid decarboxylase-immunoreactive neurons in the retina of different vertebrates
- Gamma-aminobutyric acid in the medial rat nucleus accumbens: Ultrastructural localization in neurons receiving monosynaptic input from catecholaminergic afferents
- Quantitative comparisons of gamma-aminobutyric acid neurons and receptors in the visual cortex of normal and dark-reared cats
- Immunocytochemical localization of gamma-aminobutyric acid (GABA) in the cat superior colliculus
- Laminar distribution and morphology of gamma-aminobutyric acid (GABA)-immunoreactive neurons in the medial and dorsomedial areas of the cerebral cortex of the lizard Podarcis hispanica
- Immunocytochemistry of gamma-aminobutyric acid, glutamate, serotonin, and histamine in Necturus taste buds
- Development changes in the distribution of gamma-aminobutyric acid-immunoreactive neurons in the embryonic chick lumbosacral spinal cord
- Gamma-aminobutyric acid in the nervous system of a planarian
- A topographically organized gamma-aminobutyric acid projection from the ventral pallidum to the nucleus accumbens in the rat
- Expression of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter in the rat retina
- Parvalbumin immunoreactivity in the thalamus of guinea pig: Light and electron microscopic correlation with gamma-aminobutyric acid immunoreactivity
- Postsynaptic gephyrin immunoreactivity exhibits a nearly one-to-one correspondence with gamma-aminobutyric acid-like immunogold-labeled synaptic inputs to sympathetic preganglionic neurons