Buy Amlovas pills 5 mg, 30 pcs
  • Buy Amlovas pills 5 mg, 30 pcs


Amlodipine is a calcium channel blocker that is used to treat various heart conditions, such as chest pain and hypertension. Amlodipine often sold as combined medication, in combination with other cardiac drugs.

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Clinical Pharmacology

Amlodipine blocks the entry of calcium ions through the cell membranes into the smooth muscle cells of the myocardium and blood vessels. It has a direct relaxing effect on vascular smooth muscle, expands peripheral arterioles, which leads to a reduction in round neck, reduces the load on the heart and reduces the myocardial oxygen demand, expands the coronary arteries, increasing the oxygen supply to the myocardium.


  • Arterial hypertension (monotherapy and in combination with thiazide diuretics, ACE inhibitors or alpha and beta-blockers).
  • Angina pectoris (stable and unstable, including Prinzmetala or variant).
  • Dilatational (non-ischemic) cardiomyopathy with a severe form of chronic heart failure.


1 tablet contains:

Active substance: Amlodipine 5 mg.

Amlodipine is marketed under different brands and generic names, and comes in different dosage forms:

Brand nameManufacturerCountryDosage form
Amlovas Yunik Pharmaceutical India pills
Amlodipine Canonpharma Russia pills
Amlodipine Hemofarm Serbia pills
Amlodipine Vertex Russia pills
Amlorus Synthesis AKOMP Russia pills
Amlodipine Sandoz Sandoz Switzerland pills
Amlodipine-Teva Teva Israel pills
Amlotop Hemofarm Serbia pills
Tenox Krka dd Novo mesto AO Slovenia pills
Normodipine Gedeon Richter Hungary pills
Norvasc Pfizer USA pills

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Dosage and Administration

Orally, the initial dose of 5 mg / day, if necessary, the daily dose may be increased to 10 mg. The maximum daily dose of 10 mg.

Adverse reactions

From the nervous system and sense organs: dizziness, headache, drowsiness, feeling tired; rarely, mood changes, asthenia, convulsions, myalgia, blurred vision, paresthesia.

Since the cardiovascular system and blood (hematopoiesis, hemostasis): palpitations, hot flashes.

On the part of the digestive tract: nausea, abdominal pain, dyspepsia; rarely - gingival hyperplasia, elevated levels of hepatic transaminases, jaundice.

From the genitourinary system: increased urination, swelling, impotence.

On the part of the skin: allergic reactions (skin rash, itching), rarely - erythema multiforme.

Other: rarely - shortness of breath, gynecomastia.


Hypersensitivity, hypotension.

Carefully: should be prescribed to patients with impaired liver function, stenosis of the aortic orifice, chronic heart failure.

Pregnancy and Lactation

It is possible only if the expected effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Special instructions

It should refrain from the use of the drug in pediatric practice, since the safety and efficacy of its use in children have not been determined.

Precautions should be prescribed to patients with impaired liver function, stenosis of the aortic mouth, and chronic heart failure.


Symptoms: severe hypotension.

Treatment: maintaining the function of the cardiovascular system, monitoring the performance of the heart and lungs, the elevated position of the extremities, control of the BCC and diuresis, the use of vasoconstrictor agents, the introduction of calcium gluconate (IV).

  • Brand name: Amlovas
  • Active ingredient: Amlodipine
  • Dosage form: Pills.
  • Manufacturer: Yunik Pharmaceutical
  • Country of Origin: India

Studies and clinical trials of Amlodipine (Click to expand)

  1. Quantitative Determination of Amlodipine in Serum by Liquid Chromatography with Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry
  2. Enzyme linked immunosorbent assay for determination of amlodipine in plasma
  3. Determination of Amlodipine in Pharmaceutical Formulations by Differential-Pulse Voltammetry with a Glassy Carbon Electrode
  4. Amlodipine bioequivalence study: quantification by liquid chromatography coupled to tandem mass spectrometry
  5. Negligible pharmacokinetic interaction between oral DA-8159, a new erectogenic, and amlodipine in rats
  6. Pharmacokinetics of oral amlodipine orotate in vagotomized dogs
  7. Development and validation of a highly sensitive and robust LC-ESI-MS/MS method for simultaneous quantitation of simvastatin acid, amlodipine and valsartan in human plasma: application to a clinical pharmacokinetic study
  8. Simultaneous determination of atorvastatin, amlodipine, ramipril and benazepril in human plasma by LC-MS/MS and its application to a human pharmacokinetic study
  9. Sensitive and rapid liquid chromatography/tandem mass spectrometry assay for the quantification of amlodipine in human plasma
  10. A rapid and sensitive liquid chromatography–tandem mass spectrometry (LC-MS/MS) method for the estimation of amlodipine in human plasma
  11. ChemInform Abstract: Synthesis of Amlodipine Using Aza Diels—Alder Reaction.
  12. ChemInform Abstract: Sequential Synthesis of a New Analogue (Ib) of Amlodipine (Ia) Bearing a Short Amino Polyethyleneglycol Chain.
  13. ChemInform Abstract: Advances in the Development of Methods for the Synthesis of Dihydropyridine Calcium Channel Blockers [Nifedipine (Adalat), Felodipine (Plendil), Amlodipine Besylate (Norvasc), Azelnidipine (Calblock)]
  14. Effect of cytochrome P450 3A5*3 genotype on the stereoselective pharmacokinetics of amlodipine in healthy subjects
  15. Stereoselective plasma protein binding of amlodipine
  16. Enantioselective disposition of oral amlodipine in healthy volunteers
  17. Central composite design for the rapid optimisation of ruggedness and chiral separation of amlodipine in capillary electrophoresis
  18. CJX2, an amlodipine derivative, reverses p-glycoprotein-mediated multidrug-resistance in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells
  19. Interaction of CJX2, an amlodipine derivative with human P-glycoprotein ATPase activity
  20. Effect of CJX2, an amlodipine derivative, combined with verapamil on P-glycoprotein efflux function in vitro
  21. Electroanalytical Studies and Simultaneous Determination of Amlodipine Besylate and Atorvastatine Calcium in Binary Mixtures Using First Derivative of the Ratio-Voltammetric Methods
  22. Development of a stability-indicating CE assay for the determination of amlodipine enantiomers in commercial tablets
  23. Amlodipine and atorvastatin exert protective and additive effects via antiapoptotic and antiautophagic mechanisms after transient middle cerebral artery occlusion in Zucker metabolic syndrome rats
  24. Phase transformations of amlodipine besylate solid forms

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