Buy Reglisam  granules 25 mg sachets 30 pcs
  • Buy Reglisam  granules 25 mg sachets 30 pcs

Ammonium Glycyrrhizinate

528 Items
2019-09-19
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$38.19
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Clinical Pharmacology

Pharmacotherapeutic group
Anti-inflammatory agent.
Pharmacological properties
It has anti-inflammatory, moderate expectorant effect, stimulates the function of the adrenal cortex.

Indications

Diseases of the respiratory tract with sputum difficult to separate, including mild forms of bronchial asthma (as part of complex therapy). Allergic dermatitis, eczema, Addison's disease [diencephalic-pituitary form, alone and in combination with adrenocorticotropic hormone (ACTH)] asthenic states and hypotonic syndrome hypofunction adrenocortical on long-term therapy with glucocorticosteroids, including the prevention of withdrawal syndrome during the cessation of treatment glucocorticosteroids or reduce their dosage.

Composition

Composition for one package
Active substance:
Glycyram (Ammonium Glycyrrhizinate) in terms of 100% substance - 0.025 g
Auxiliary substances:
Sodium hydrocitrate (disubstituted) - 0.050 g
Potato starch - 0,010 g
Milk sugar (lactose monohydrate) - 1.215 g
The mass of granules in the package - 1.3 g

Ammonium Glycyrrhizinate is marketed under different brands and generic names, and comes in different dosage forms:

Brand nameManufacturerCountryDosage form
Reglisam granules
Glyciram Vifiteh Russia pills

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Ammonium Glycyrrhizinate

Dosage and Administration

For oral use. 30 minutes after eating in the form of an aqueous solution, which is prepared before use by dissolving the contents of one packet (1.3 g) in 1 tablespoon (15 ml) of warm boiled water (single dose).
The drug is prescribed to children in accordance with age:

  • from 5 months to 3 years - 2 times a day;
  • from 3 to 5 years - 3 times a day;
  • from 5 to 10 years - 3-4 times a day.
Course treatment - from 3 to 30 days. Repeated courses are possible in consultation with the doctor. Children over 10 years old glycyram prescribed in the dosage form of pills of 50 mg.

Adverse reactions

Allergic reactions are possible. In this case, the drug should be discontinued. If any of the side effects indicated in the instructions are aggravated or you notice any other side effects that are not indicated in the instructions, inform your doctor.

Contraindications

Hypersensitivity to the components of the drug, severe organic lesions of the heart and parenchymal organs, impaired liver and kidney function, age up to 5 months, lactase deficiency, lactose intolerance, glucose-galactose malabsorption. If you have one of these diseases, be sure to consult your doctor before taking the drug.

Drug interactions

Perhaps enhancing the action of drugs that stimulate the function of the adrenal cortex.

Special instructions

Patients with diabetes and those on a low carbohydrate diet should take into account that about 1.22 g of carbohydrates (0.1 XE) are contained in one package of the drug.
Carefully
Patients with diabetes.
Use during pregnancy and during breastfeeding
Not applicable. The drug is intended for use in children up to 10 years.
Influence on ability to drive and work with mechanisms
Not applicable. The drug is intended for use in children up to 10 years.

Overdosage

Possible violation of the liver.
Symptomatic treatment.

  • Brand name: Reglisam
  • Active ingredient: Ammonium Glycyrrhizinate
  • Dosage form: Granules for the preparation of oral solution for children 25 mg. At 1.3 g in bags of paper packaging with plastic coated or laminated paper. 10 or 30 packages together with the application instruction in a pack from a cardboard.
  • Manufacturer: Orion Corporation

Studies and clinical trials of Ammonium Glycyrrhizinate (Click to expand)

  1. Chitosan nanoparticles as a novel delivery system for ammonium glycyrrhizinate
  2. Lack of Effect of Ammonium Glycyrrhizinate on the Morphology of Ovine Nasal Mucosain Vitro
  3. In VitroNasal Transport Across Ovine Mucosa: Effects of Ammonium Glycyrrhizinate on Electrical Properties and Permeability of Growth Hormone Releasing Peptide, Mannitol, and Lucifer Yellow
  4. Ammonium glycyrrhizinate (AMGZ) effects on membrane integrity
  5. Ethosomes for skin delivery of ammonium glycyrrhizinate: In vitro percutaneous permeation through human skin and in vivo anti-inflammatory activity on human volunteers
  6. Anti-inflammatory activity of novel ammonium glycyrrhizinate/niosomes delivery system: Human and murine models
  7. Teratogenicity study of ammonium glycyrrhizinate in the Sprague-Dawley rat
  8. Ammonium Glycyrrhizinate Protects Gastric Epithelial Cells from Hydrogen Peroxide-Induced Cell Death
  9. Self-assembly of polyion complex nanocarriers from ammonium glycyrrhizinate and monomethoxy poly(ethylene glycol)-b-poly(γ-amino-ε-caprolactone)
  10. Final Report on the Safety Assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate
  11. Cardioprotective effect of ammonium glycyrrhizinate against doxorubicin-induced cardiomyopathy in experimental animals
  12. THE ACTION OF MONO-AMMONIUM GLYCYRRHIZINATE ON ADRENALECTOMIZED SUBJECTS AND ITS SYNERGISM WITH HYDROCORTISONE
  13. Quaternized Chitosan (QCS) Nanoparticles as a Novel Delivery System for Ammonium Glycyrrhizinate
  14. Deformable Surfactant Vesicles Loading Ammonium Glycyrrhizinate: Characterization and In Vitro Permeation Studies
  15. Ammonium glycyrrhizinate-loaded niosomes as a potential nanotherapeutic system for anti-inflammatory activity in murine models
  16. Study of an Acid-Free Technique for the Preparation of Glycyrrhetinic Acid from Ammonium Glycyrrhizinate in Subcritical Water

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