Apis-Plus
Dr. N
833 Items
2019-09-19
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Clinical Pharmacology
Multicomponent homeopathic medicine, whose action is due to the components that make up its composition.
Indications
In the treatment of chronic salpingoophoritis, nonspecific prostatitis.
Composition
1 rectal homeopathic suppository contains:
- Apis mellifica (Apis) (Aplicus mellifica (Apis)) NW - 0.2 g.
- Pulsatilla pratensis (Pulsatilla) (Pulsatilla Pratensis (Pulsatilla)) NW - 0.2 g.
- Cimicifuga racemosa (Cimicifuga) (cimicifuga racemosis (cimicifuga)) NW - 0.2 g
- Calendula officinalis (Calendula) (calendula ofitsinalis (calendula)) NW - 0.2 g
- Thuja occidentalis (Thuja) (thuja occidentalis (thuja)) NW - 0.2 g.
Excipients:
Anhydrous lanolin (lanolin) - 0.08 g; cocoa butter up to 1.5 g
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Dosage and Administration
Enter into the rectum and 1 candle 1 time per day for the night after performing hygiene procedures. The course of treatment is 8 weeks.
Adverse reactions
Allergic reactions are possible.
Contraindications
Individual intolerance to the drug Apis-plus.
Drug interactions
Perhaps the simultaneous use of other drugs.
Pregnancy and Lactation
Not recommended.
Special instructions
Addiction to the drug or "withdrawal syndrome" is not marked. In the absence of a therapeutic effect, as well as the appearance of side effects that are not described in the instructions, you should consult a doctor.
Influence on ability to drive motor transport and control mechanisms
Does not affect.
Overdosage
Overdose cases have not yet been reported.
Paracetamol reduces the efficacy of uricosuric drugs. The concomitant use of paracetamol in high doses increases the effect of anticoagulant drugs. Inductors of microsomal oxidation in the liver (phenytoin, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants), ethanol and hepatotoxic drugs increase the production of hydroxylated active metabolites, which makes it possible to develop severe intoxication even with a small overdose.With simultaneous use with metoclopramide may increase the rate of absorption of paracetamol. Prolonged use of barbiturates reduces the effectiveness of paracetamol. Inhibitors of microsomal oxidation reduce the risk of hepatotoxic action.
Rimantadin stimulates the stimulating effect of caffeine. Cimetidine reduces the clearance of rimantadine by 18%.
Ascorbic acid increases the concentration of benzylpenicillin in the blood. It improves the absorption of iron preparations in the intestine (converts ferric iron to ferrous iron); may increase the excretion of iron while using with deferoxamine. Increases the risk of crystalluria in the treatment of short-acting salicylates and sulfonamides, slows the kidneys excretion of acids, increases the excretion of drugs having an alkaline reaction (including alkaloids). Reduces the concentration in the blood of oral contraceptives. Increases total clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body. With simultaneous use reduces the chronotropic effect of isoprenaline. Barbiturates and primidone increase the excretion of ascorbic acid in the urine. Reduces the therapeutic effect of antipsychotic drugs (neuroleptics) - phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants.
Loratadine. Inhibitors of CYP3A4 and CYP2D6 increase the concentration of loratadine in the blood.
Pregnancy and Lactation
Use during pregnancy and during breastfeeding is contraindicated.
Special instructions
Duration of use - no more than 5 days.
Do not use in the presence of metastatic tumors.
Persons prone to ethanol use should consult a doctor before starting treatment with the drug, since paracetamol may have a damaging effect on the liver.
Impact on the ability to drive vehicles and other mechanisms that require increased concentration of attention: during the period of treatment, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.
Overdosage
- Symptoms: during the first 24 hours after administration - pallor of the skin, nausea, diarrhea, vomiting, pain in the epigastric region; violation of glucose metabolism, metabolic acidosis (including lactic acidosis), hypokalemia, tachycardia, arrhythmia, headache, exacerbation of concomitant chronic diseases. Symptoms of abnormal liver function may appear 12-48 hours after an overdose. In severe overdose - liver failure with progressive encephalopathy, coma; acute renal failure with tubular necrosis (including in the absence of severe liver damage). The overdose threshold may be reduced in elderly patients, in patients taking certain drugs (for example, inducers of microsomal liver enzymes), alcohol or suffering from depletion.
- Treatment: the introduction of SH-group donators and precursors of the synthesis of glutathione - methionine within 8-9 hours after overdose and acetylcysteine - within 8 hours. Gastric lavage, symptomatic therapy. The need for additional therapeutic measures (further introduction of methionine, acetylcysteine) is determined depending on the concentration of paracetamol in the blood, as well as the time elapsed after its administration.
- Brand name: AnviMax®
- Active ingredient: Paracetamol, Ascorbic acid, Rimantadine, Rutozid, Loratadine, Calcium gluconate
- Dosage form: Effervescent pills [with cranberry taste and aroma], effervescent pills [with raspberry taste and aroma]. On 10 pills in a tub from polypropylene complete with a cover from polyethylene with a silica gel insert.
On 1 tuba together with the application instruction in a pack from a cardboard. - Manufacturer: FarmVILAR FPK
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