Ascorbic acid, Calcium carbonate
- done All payments are SSL encrypted
- done Full Refund if you haven't received your order
- done International shipping to the USA, UK and Europe
It is recommended as a dietary supplement, a source of vitamin C and calcium.
Calcium + vitamin C is recommended:
- To maintain the work of the musculoskeletal and nervous tissues of the body;
- With fatigue and physical exertion;
- For better recovery after injuries;
- With allergic reactions;
- In infectious and inflammatory processes in the body.
calcium carbonate (200 mg), ascorbic acid (300 mg), auxiliary components: citric acid, sodium bicarbonate, dextrose, sorbitol, aspartame, polyethylene glycol (E1521), flavoring.
Ascorbic acid, Calcium carbonate is marketed under different brands and generic names, and comes in different dosage forms:
|Brand name||Manufacturer||Country||Dosage form|
|Supra vit||Candy Ltd BG||Bulgaria||effervescent pills|
|Calcium + Vitamin C||Natur Product Pharma||Poland||effervescent pills|
No customer reviews for the moment.
Dosage and Administration
The drug is intended for use in the oral cavity and can be administered only in
tissues where there is no inflammation.
Injection into inflamed tissue is not allowed.
The drug can not be administered intravenously.
In order to avoid accidental ingestion of the drug in the blood vessels, before
its introduction should always be carried out aspiration test (in two stages).
Major systemic reactions that may develop as a result of random
intravascular administration of the drug can be avoided by following the injection technique:
after the aspiration test, 0.1-0.2 ml of the drug is slowly injected, then, not
earlier than 20-30 seconds, slowly inject the rest of the dose. Pressure
injections should match the sensitivity of the tissue.
For anesthesia with uncomplicated removal of the teeth of the upper jaw in the absence of
inflammation is usually sufficient to create a depot of the drug in the area of the transition fold
by introducing it into the submucosa from the vestibular side (1.7 ml of the drug per
tooth). In rare cases, complete anesthesia may be required.
additional administration from 1 ml to 1.7 ml. In most cases, this allows not
carry out painful palatal injections. When deleting several near
placed teeth, it is usually possible to limit the number of injections.
For anesthesia with cuts and suturing in the palate to create the palatine
A depot requires about 0.1 ml of the drug per injection.
In the case of removal of premolars of the lower jaw, in the absence of inflammation,
do without mandibular anesthesia, as is usually sufficient
infiltration anesthesia provided by the injection of 1.7 ml per tooth. If so
by not achieving the desired effect, additional
injection of 1-1.7 ml of anesthetic into the submucosa in the region of the transitional fold of the lower
jaws from the vestibular side. If in this case it was not possible to achieve complete
anesthesia, it is necessary to conduct a conductive blockade of the mandibular nerve.
When processing cavities and grinding teeth under the crowns, with the exception of the lower
molars, depending on the volume and duration of treatment is shown
the introduction of the drug Certacainum 40 mg / ml + 0.005 mg / ml in the transition fold region with
vestibular side in a dose of 0.5-1.7 ml per tooth.
During surgery, the drug Certacainum 40 mg / ml + 0.01 mg / ml in
Depending on the severity and duration of the intervention is dosed individually.
When performing a single medical procedure, adults can enter Articaine in a dose up to
7 mg per 1 kg of body weight. Patients were well tolerated in doses up to 500 mg.
(corresponds to 12.5 ml of solution for injection).
For pediatric patients (over 4 years old), minimal doses should be applied,
necessary to achieve adequate anesthesia, the dose of the drug Certacain
is selected depending on the age and body weight of the child, but the dose of articaine is not
should exceed 7 mg per 1 kg of body weight (0.175 ml / kg). Use of the drug in children
younger than 1 year has not been studied.
For elderly patients and all patients with severe renal and hepatic
insufficiency may create elevated plasma concentrations
Articaine. For these patients, the minimum dose required for
achieve sufficient depth of anesthesia
The frequency of side effects is presented in accordance with the classification,
recommended by the World Health Organization:
very often (≥ 1/10);
often (≥ 1/100, <1/10);
infrequently (≥ 1/1000, <1/100);
rarely (≥ 1/10000, <1/1000);
very rarely (<1/10000), including individual messages;
frequency is unknown (according to the available data, determine the frequency of occurrence
Nervous system disorders
Often: paresthesia, hypesthesia; headache mainly due to
composition of the drug epinephrine.
Frequency unknown: dose-dependent reactions from the central nervous system:
agitation, nervousness, stupor, sometimes progressive to loss of consciousness, coma,
respiratory disorders, sometimes progressing to respiratory arrest, muscular
tremor, muscle twitching, sometimes progressive to generalized
Sometimes in violation of the correct injection technique with the introduction
damage to local anesthetics in dental practice
facial nerve, which can lead to the development of facial paralysis.
Violations by the organ of vision
Frequency unknown: visual impairment (blurred vision,
mydriasis, blindness, double vision), usually reversible and occurring during or
shortly after injection of a local anesthetic.
Disorders of the gastrointestinal tract
Often: nausea, vomiting.
Violations of the heart and blood vessels
Infrequently: tachycardia, disturbance of a heart rhythm, increase in arterial pressure.
Frequency unknown: lower blood pressure, bradycardia, cardiac
failure and shock.
Immune system disorders
Frequency unknown: allergic reactions (swelling and inflammation at the injection site),
hyperemia of the skin, itching, conjunctivitis, rhinitis, angioedema (edema
upper and / or lower lips, cheeks, vocal cords swelling with a "lump in the throat",
difficulty swallowing, hives, difficulty breathing). Any of these manifestations
may progress to anaphylactic shock.
General disorders and disorders at the site of administration
Frequency unknown: occasional intravascular injection may result
zones of ischemia at the injection site, up to tissue necrosis.
Hypersensitivity to articaine or other local anesthetic
amide-type agents, epinephrine, sulfites (in particular, in patients suffering from
bronchial asthma with increased sensitivity to sulfites, as possible
acute allergic reactions with symptoms of anaphylactic shock, such as
bronchospasm), or to any other of the auxiliary components of the drug.
Contraindications due to the presence in the composition of the drug Articaine
- severe sinus dysfunction or severe conduction disorders
(for example, severe bradycardia, atrioventricular block II or III degree);
- acute decompensated heart failure;
- severe arterial hypotension.
Contraindications due to the presence in the composition of the drug epinephrine
- angle-closure glaucoma;
- hyperfunction of the thyroid gland;
- paroxysmal tachycardia, tachyarrhythmia;
- recent myocardial infarction (up to 6 months);
- recently transferred coronary artery bypass surgery (up to 3 months);
- taking non-selective beta-blockers, for example, propranolol (risk
hypertensive crisis and severe bradycardia);
- severe form of arterial hypertension.
- in patients with chronic heart failure, coronary artery disease
heart, angina, atherosclerosis, myocardial infarction in history, impaired
heart rhythm, hypertension;
- in patients with cerebrovascular disorders, history of stroke;
- in patients with chronic bronchitis, emphysema;
- in patients with diabetes mellitus (potential risk of changes in concentration
- in patients with cholinesterase deficiency (use is possible only in the case of
absolutely necessary, since it is possible prolongation and a pronounced increase
- in patients with bleeding disorders;
- in patients with severe violations of the liver and kidneys;
- in patients with marked arousal;
- in patients with epilepsy in history;
- when combined with halogen-containing agents when conducting
Simultaneous use is contraindicated
With simultaneous use with non-cardio selective beta-blockers,
for example, propanolol, may develop hypertonic crisis and severe
Simultaneous use is possible with caution.
The action of vasoconstrictors that increase blood pressure, for example,
epinephrine may be enhanced by tricyclic antidepressants or
monoamine oxidase inhibitors.
Local anesthetics enhance the effect of drugs
depressing the central nervous system. Narcotic analgesics increase
action of local anesthetics, however, increase the risk of respiratory depression.
When using the drug Tsertacain in patients taking heparin or
acetylsalicylic acid, may develop bleeding at the injection site.
With simultaneous use with cholinesterase inhibitors may slow down
metabolism of local anesthetics, resulting in possible
prolongation and pronounced enhancement of the action of Articaine.
Epinephrine can inhibit insulin release from pancreatic beta cells
glands and reduce the effects of hypoglycemic agents for oral administration.
Some means of inhalation anesthesia, such as halothane, may increase
myocardial sensitivity to catecholamines and increase the risk of developing disorders
heart rate after injection of the drug Certacain.
When processing the injection site of a local anesthetic with disinfectant solutions,
containing heavy metals, increases the risk of local reactions - edema,
Regional and local anesthesia should be performed by experienced professionals in
an appropriately equipped room with the availability of ready to
immediate use of equipment and preparations necessary for
monitoring of cardiac activity and resuscitation. Staff,
performing anesthesia must be qualified and trained
performing anesthesia, must be familiar with the diagnosis and treatment of systemic
toxic reactions, adverse events, reactions and other complications.
To prevent infection (including the hepatitis virus)
make sure that new solutions are always used when taking the solution from the ampoules
sterile syringes and needles.
In order to avoid the development of adverse reactions, it is necessary to apply minimal
effective doses of the drug and before the introduction of the drug to conduct a two-step
aspiration test (see the section "Route of Administration and Doses").
When using the drug may inadvertently injuring the lips, cheeks,
mucous membrane and tongue, especially in children, due to reduced sensitivity.
The patient should be warned that food is possible only after
termination of local anesthesia and recovery of sensitivity.
The drug is intended for use in dentistry. Use for anesthesia
distal extremities is unacceptable due to the risk of ischemia due to
Impact on the ability to drive vehicles and mechanisms
The possibility of admission of the patient to the management of vehicles and mechanisms
determined by a doctor.
The most common symptoms are cardiovascular reactions.
system and nervous system, nausea, motor restlessness, clouding of consciousness
during injection, respiratory disorders, muscle twitching, convulsions, shock.
Symptomatic treatment. When first signs of overdose appear or
side effects such as nausea, motor restlessness, turbidity
consciousness during the injection, it should be interrupted, the patient transferred to the horizontal
position, clear airway, monitor heart rate and blood pressure.
It is recommended, even if the symptoms do not seem too severe, to ensure
intravenous access. For respiratory disorders, depending on the severity, give
oxygen, in some cases, conduct artificial respiration. Central
analeptics are contraindicated. Muscle twitching or generalized cramps
removed by intravenous injection of short or ultrashort barbiturates
actions. Falling blood pressure, tachycardia or bradycardia often
are eliminated when the patient is placed in a horizontal position. With severe
circulatory disorders and shock of any genesis after stopping the injection
emergency measures are shown: ensuring the airway (oxygen
insufflation), intravenous fluids (electrolyte solution),
glucocorticosteroids. Additionally, you can enter plasma substitutes, albumin.
With a threatening circulatory disorder and increasing bradycardia, it is administered from
0.25 ml to 1 ml epinephrine. An intravenous injection of epinephrine should be made.
slowly under the control of heart rate and blood pressure.
A single dose of intravenous injection of epinephrine should not exceed 0.1 mg, in
Further, if necessary, epinephrine can be administered dropwise (rate of infusion
through dropper is adjusted depending on the pulse rate and blood pressure).
Severe forms of tachycardia and tachyarrhythmias can be eliminated by using
antiarrhythmic drugs, but do not use non-selective beta
adrenergic blockers. Oxygen supply and blood circulation control are needed in
anyway. With an increase in blood pressure in patients suffering
hypertension, should, if necessary, apply peripheral
- Brand name: Certacain
- Active ingredient: Articaine, Epinephrine
- Dosage form: Injection
- Manufacturer: Graminexx