Buy Aspirin Complex tea bags 3.5 g, 10 pcs
  • Buy Aspirin Complex tea bags 3.5 g, 10 pcs

Aspirin Complex

Bayer Pharma AG
1584 Items
2019-09-19
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$33.45
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Clinical Pharmacology

Aspirin Complex is a combination drug.
Acetylsalicylic acid has antipyretic, analgesic and anti-inflammatory effects, and also reduces platelet aggregation.
Phenylephrine It is a sympathomimetic and, having a vasoconstrictor effect, reduces swelling of the mucous membranes of the nose and paranasal sinuses, resulting in easier breathing.
Chlorphenamine - histamine H blocker1-receptors, has anti-allergic effect: eliminates itching (including eyes, nose), swelling and hyperemia of the mucous membranes of the nasal cavity, nasopharynx and sinuses, reduces the phenomenon of exudation.

Indications

Use to relieve symptoms of “colds”, acute respiratory viral infections, flu, such as: fever and chills, headache and muscle pain, runny nose and / or nasal congestion, sore throat and sneezing.

Composition

Each bag contains: active ingredients: acetylsalicylic acid - 500 mg, phenylephrine hydrotartrate - 15.58 mg, chlorphenamine maleate - 2.00 mg; excipients: anhydrous citric acid 1220 mg, sodium bicarbonate 1709.6 mg, lemon flavor 100 mg, quinoline yellow dye (E 104) 0.32 mg.

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Aspirin Complex

Dosage and Administration

Inside Dissolve the effervescent tablet in a glass of water and drink after a meal.
With pain syndrome of weak and medium intensity and feverish conditions, a single dose is 1 -2 effervescent pills, the maximum single dose is 2 effervescent pills, the maximum daily dose should not exceed 6 pills. The intervals between doses of the drug should be at least 4 hours.
The duration of treatment (without consulting a doctor) should not exceed 3-5 days.
In order to reduce the risk of adverse reactions from the gastrointestinal tract, the minimum effective dose of the drug should be applied by the shortest course of treatment.

Adverse reactions

Violations of the gastrointestinal tract: often - loss of appetite; rarely diarrhea; frequency unknown - dyspepsia, abdominal pain, nausea, vomiting, overt (black stool, bloody vomiting) or hidden signs of gastrointestinal bleeding that can lead to iron deficiency anemia, erosive-ulcerative lesions (including perforations) of the gastrointestinal tract.
Nervous system disorders: infrequently - headache; frequency is unknown - dizziness, tinnitus (usually are signs of overdose).
Violations of the blood and lymphatic system: the frequency is unknown - hemorrhagic syndrome, thrombocytopenia. Bleeding can lead to acute or chronic anemia, iron deficiency anemia with appropriate laboratory and clinical manifestations (asthenia, pallor, hypoperfusion). Patients with glucose-6-phosphate dehydrogenase deficiency may experience hemolysis and hemolytic anemia.
Disturbances of the kidneys and urinary tract: the frequency is unknown - when used in high doses - hyperoxaluria and the formation of urinary stones from calcium oxalate, damage to the glomerular apparatus of the kidneys.
Immune system disorders: the frequency is unknown - skin rash, rhinitis, anaphylactic reactions, bronchospasm, angioedema, the formation of an "aspirin triad" (bronchial asthma, polypous rhinosinusitis, and intolerance to acetylsalicylic acid and pyrazolone preparations).
Disorders of the liver and biliary tract: very rarely - Reye's syndrome (acute fatty degeneration of the liver with developed acute liver failure and encephalopathy); rarely, liver dysfunction (increased hepatic transaminases).
When these symptoms appear, it is recommended to stop taking the drug and immediately contact your doctor.

Children's age (up to 15 years); hypersensitivity to any component of the drug and other NSAIDs; erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase), gastrointestinal bleeding; inflammatory bowel disease in the acute stage; complete or incomplete combination of asthma, recurrent polyposis of the nasal mucosa and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs, including a history of; combined use of methotrexate at a dose of 15 mg per week or more; severe violations of the liver, kidneys; severe cardiac dysfunction; hemorrhagic diathesis; hemophilia, thrombocytopenia; deficiency of glucose-6-phosphate dehydrogenase; vitamin K deficiency; cerebrovascular or other bleeding; simultaneous administration of oral anticoagulants and acetylsalicylic acid in a dose exceeding 3 g per day; pregnancy (I and III trimesters), breastfeeding period.

With caution: with concomitant therapy with anticoagulants, gout, gastric ulcer and / or duodenal ulcer (in history), erosive gastritis, and propensity for gastrointestinal bleeding, impaired liver function, hypothrombinemia, hypovitaminosis K, anemia, condition of therapists, therapists, therapists, therapists, therapies, therapists, hepatitis, hypothrombinemia, hypovitaminosis K, anemia, conditions of therapists, therapists, therapists, therapists, hepatitis, hypothrombinemia, hypovitaminosis K, anemia, the condition of the chromic prostate glands, disorders of the liver, hypothrombinemia, hypovitaminosis K, anemia, prostatitis in the body (includingdysfunction of the heart, arterial hypertension), thyrotoxicosis, tendency to calcium-oxalate nephrolithiasis. Bronchial asthma, nasal polyposis, pollinosis, drug allergy, hypermenorrhea.

Drug interactions

The combined use of aspirin and anticoagulants increases the risk of bleeding.

With the simultaneous use of the drug Aspirin and NSAIDs increase the main and side effects of the latter.
During treatment with Aspirin, the side effect of methotrexate is aggravated.

With the simultaneous use of Aspirin and oral hypoglycemic drugs - sulfonylurea derivatives, there is an increase in the hypoglycemic effect.
At simultaneous use with GKS increases the risk of gastrointestinal bleeding.

With the simultaneous use of Aspirin weakens the effect of spironolactone, furosemide, antihypertensive drugs, as well as anti-gout agents that promote the excretion of uric acid.

The prescription of antacid agents during treatment with Aspirin (especially in doses of more than 3 g for adults and more than 1.5 g for children) can cause a decrease in the high steady-state level of salicylate in the blood.

Pregnancy and Lactation

contraindicated in the I and III trimester and during breastfeeding. In the II trimester of pregnancy, you can assign occasionally and with caution.

Special instructions

The drug is not prescribed as an antipyretic for children under 15 years of age with acute respiratory infections caused by viral infections, due to the risk of Reye's syndrome. Acetylsalicylic acid reduces the excretion of uric acid from the body, which can cause an acute attack of gout in predisposed patients. Drug interactions are possible. Glucocorticosteroids, alcohol increase the damaging effects on the gastrointestinal mucosa. One dose of the drug contains 933 mg of sodium, which should be considered in patients receiving salt-free diet. In order to reduce the risk of increased bleeding, the drug should be canceled 4-8 days before the planned surgical intervention.

Overdosage

Symptoms: with mild intoxication, nausea, vomiting, epigastric pain, and also (especially in children and elderly patients) tinnitus, dizziness, headaches, loss of vision and hearing are possible.

With a significant overdose, incoherent thinking, confusion, drowsiness, collapse, tremor, shortness of breath, suffocation, dehydration, hyperthermia, coma, alkaline urine reaction, metabolic acidosis, respiratory (gas) alkalosis, and carbohydrate metabolism disorders appear.

Lethal dose of acetylsalicylic acid for adults - more than 10 g, for children - more than 3 g.

Treatment: Depending on the state of acid-base balance and electrolyte balance, solutions of sodium bicarbonate, sodium citrate or sodium lactate are infused.

  • Brand name: Aspirin C
  • Active ingredient: Acetylsalicylic acid, Ascorbic acid
  • Dosage form: Effervescent pills
  • Manufacturer: Bayer Pharma AG
  • Country of Origin: Germany

Studies and clinical trials of Aspirin Complex (Click to expand)

  1. Osmium(VIII) catalysed and uncatalysed oxidation of aspirin drug by diperiodatocuprate(III) complex in aqueous alkaline medium: A mechanistic approach
  2. Synthesis, characterization and bioactivity of a new VO2+/Aspirin complex
  3. The crystal and molecular structure of the β-cyclodextrin inclusion complex with aspirin and salicylic acid
  4. Management of Complex Two-chamber False Aneurysms by Thrombin Injections in Patients Under Clopidogrel, Aspirin or Both
  5. Complex formation between transition metal ions and salicylglycine, a metabolite of aspirin
  6. Biochemical properties and mechanism of action of a vanadyl(IV) – aspirin complex on bone cell lines in culture
  7. Effects of aspirin and prostaglandin E2on interdigestive motility complex and duodenogastric reflux in man
  8. Studies on the metal-complex of acetyl salicylic acid (aspirin)
  9. Zinc-aspirin complex: synthesis, physicochemical and biological evaluation
  10. The factor VIII complex in atherosclerosis: Effects of aspirin
  11. A pioneer study on the anti-ulcer activities of copper nicotinate complex [CuCl (HNA)2] in experimental gastric ulcer induced by aspirin-pyloris ligation model (Shay model)
  12. Comparative Binding Effects of Aspirin and Anti-Inflammatory Cu Complex in the Active Site of LOX-1
  13. Pharmacology: Effects of Copper-aspirin Complex on Platelet Aggregation and Thrombosis in Rabbits and Mice
  14. The heparin-aspirin complex action on the fibrinolysis and insular system at experimental diabetes
  15. Aspirin Therapy for Colorectal Cancer With PIK3CA Mutation: Simply Complex!
  16. T1143 Reduction of Gastroduodenal Ulceration With Aspirin-Phosphatidylcholine Complex Versus Aspirin—Potential Importance of Local Mucosal Injury
  17. Molecular behavior, dissolution characteristics and chemical stability of aspirin in the ground mixture and in the inclusion complex with di-O-methyl-β-cyclodextrin
  18. A vanadium/aspirin complex controlled release using a poly(β - propiolactone) film. Effects on osteosarcoma cells
  19. The development of fixed drug combinations – The example of Aspirin® Complex
  20. ASPIRIN AND ASTHMA: A COMPLEX INTERACTION
  21. Protective Actions of Aspirin-Triggered (17R) Resolvin D1 and Its Analogue, 17R-Hydroxy-19-Para-Fluorophenoxy-Resolvin D1 Methyl Ester, in C5a-Dependent IgG Immune Complex-Induced Inflammation and Lung Injury
  22. A Molecular Dynamics Approach to Ligand-Receptor Interaction in the Aspirin-Human Serum Albumin Complex

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