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Azithromycin is a broad-spectrum bacteriostatic antibiotic from the group of azrolide macrolides. It has a wide range of antimicrobial effects.
The mechanism of action of azithromycin is associated with inhibition of protein synthesis of microbial cells. By binding to the 50S subunit of the ribosome, it inhibits the peptide translocase at the translation stage and inhibits protein synthesis, slowing the growth and reproduction of bacteria. In high concentrations it has a bactericidal effect.
It has activity against a number of gram-positive, gram-negative, anaerobic, intracellular and other microorganisms.
Microorganisms may initially be resistant to the action of the antibiotic or may become resistant to it.
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