Blemaren®
Esparma
67 Items
2019-09-19
- done All payments are SSL encrypted
- done Full Refund if you haven't received your order
- done International shipping to the USA, UK and Europe
Clinical Pharmacology
Drug for the treatment of nephrolithiasis. Blemarine dissolves and prevents the formation of uric acid stones due to alkalization of urine to pH values of 6.6–6.8 (when urine pH is within 6.6–6.8, the dissolution of uric acid salts increases significantly).
In addition, reduces calcium excretion, improves the solubility of calcium oxalate in the urine, inhibits the formation of crystals and, therefore, prevents the formation of calcium oxalate stones.
Indications
- Prevention of formation and dissolution of uric acid and calcium oxalate stones.
- Dissolution of mixed uric acid-oxalate stones (with oxalate content <25%).
- Alkalinization of urine in persons receiving cytostatics or drugs that increase the excretion of uric acid.
- Symptomatic treatment of skin porphyria.
Composition
1 tablet contains:
Active substances: citric acid - 1.197 g; potassium bicarbonate - 967.5 mg; sodium citrate - 835,5 mg.
Excipients: lactose monohydrate - 115 mg, mannitol - 105 mg, adipic acid - 35 mg, macrogol 6000 - 100 mg, sodium saccharinate - 10 mg, lemon flavor - 35 mg.
No customer reviews for the moment.
Dosage and Administration
Before ingestion effervescent pills are dissolved in 200 ml of liquid (tea, fruit juice or alkaline mineral water). The daily dose is 2-6 tab.
The daily dose is evenly distributed throughout the day and taken after meals.
The dose is considered to be properly selected, if the urine pH during the day is in the range of 6.2 -7 - for dissolving uric acid stones; 7,5 – 8,5 - for dissolving cystine stones; 7,2-7,5 - for the treatment of porphyria; at least 7.0 - in the treatment of cytostatics.
If the urine pH value is lower than the specified one, the dose should be increased, if higher, the dose should be reduced. The duration of treatment is 4-6 months.
Efficiency control (determination of urine pH) is carried out 3 times / day, before taking each single dose using indicator paper. The resulting color on the paper is compared within 2 minutes with the scale and the resulting value is entered into the control calendar.
In the presence of cystine stones and the treatment of porphyria, special indicator paper with a pH from 7.2 to 9.7 should be used to control its effectiveness.
Adverse reactions
Maybe: allergic reactions, edema (sodium retention), metabolic alkalosis, dyspepsia.
Contraindications
- Acute and chronic renal failure.
- Metabolic alkalosis.
- Urinary tract infections caused by urea-splitting microorganisms.
- urine pH above 7.
- The need to adhere to a strict salt-free diet (for example, in severe forms of arterial hypertension).
- Hypersensitivity to the drug.
Drug interactions
With the simultaneous use of Blemaren and drugs containing citrates and aluminum, it is possible to increase the absorption of aluminum, so these drugs should be taken at intervals of at least 2 hours before or after taking Blemaren.
The composition of the drug includes potassium, therefore, with the simultaneous use of Blemaren and cardiac glycosides, the pharmacological action of the latter can be weakened.
Some antihypertensive drugs (for example, aldosterone antagonists, potassium-sparing diuretics, ACE inhibitors), NSAIDs and analgesics can reduce the excretion of potassium from the body. The question of the possibility of simultaneous use of Blemaren and the above medicines is decided by the doctor individually.
Pregnancy and Lactation
There are no data on the safety of use of Blemaren® during pregnancy and lactation, and therefore it is not recommended to use the drug during these periods.
Special instructions
The average daily dose (4 effervescent pills) contains about 1.5 mg of potassium and 0.9 g of sodium, which should be considered when prescribing the drug to patients on a diet restricting salt intake.
The drug can be used in chronic renal failure, not accompanied by a delay of potassium ions.
Perhaps the appointment of the drug to patients with diabetes.
When dissolving uric acid stones, the daily dose should not be exceeded, since when the pH rises above 7.0, phosphates precipitate on the urate crystals, which prevents their further dissolution.
During treatment, you should limit the intake of foods rich in proteins and purine bases, as well as ensure adequate fluid intake (not <1.5-2 liters="" p="">
Overdosage
Data on drug overdose Blemaren not provided.
8 other products in the same category:
arrow_upward