Boric acid
Iodine technology and marketing
1251 Items
2019-09-19
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Clinical Pharmacology
Boric acid is an antiseptic, also has an insecticidal (incl. Anti-pediculosis) effect. Coagulates proteins (including enzyme) microbial cells, violates the permeability of the cell wall. 5% aqueous solution suppresses phagocytosis, 2 4% solution retards the growth and development of bacteria. It has an irritating effect on mucous membranes, granulation tissue. Absorption has systemic toxic effects.
Pharmacokinetics
It penetrates the skin and mucous membranes; slowly excreted and may accumulate in organs and tissues. Excreted by the kidneys 50% (within 12 hours), the balance within 5-7 days.
Indications
- Otitis,
- eczema (including weeping),
- dermatitis,
- pyoderma,
- intertrigo.
Composition
1 l external solution contains:
active substance: boric acid 30.0 g,
excipient: ethyl alcohol 70% up to 1000 ml
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Dosage and Administration
For skin diseases, the affected surfaces are treated or a 3% solution in ethanol is used in the form of lotions. In acute and chronic otitis, 3-5 drops are instilled, or they are introduced as turundum into the ear canal 2-3 times a day as a 3% solution in ethanol.
Adverse reactions
- Nausea,
- vomiting
- diarrhea,
- skin rash,
- epithelial desquamation,
- headache,
- confusion,
- convulsions
- renal dysfunction.
Contraindications
- Hypersensitivity
- chronic renal failure
- acute inflammatory diseases of the skin;
- pregnancy,
- children's age (up to 3 years),
- lactation period.
Drug interactions
When applied externally, cases of interaction with other drugs are not described.
Pregnancy and Lactation
Contraindicated
Special instructions
Avoid application to mucous membranes and large body surfaces.
Overdosage
At external use of overdose it was not noted so far.
- Brand name: Boric acid
- Active ingredient: Boric acid
- Dosage form: Solution for external use
- Manufacturer: Iodine technology and marketing
- Country of Origin: Russia
Studies and clinical trials of Boric acid (Click to expand)
- Structural analysis of diols by electrospray mass spectrometry on boric acid complexes
- Thermal and rheological properties of poly(vinyl alcohol) gel with boric acid as a crosslinking agent
- The elastic property of polyvinyl alcohol gel with boric acid as a crosslinking agent
- Electroplating of a Co–Cu alloy from a citrate bath containing boric acid
- Boric acid vaginal suppositories: A brief review
- Effect of Various Impurities on the Metastable Zone Width of Boric Acid
- Effect of Electrical Field and Temperature on the Crystal Growth Rates of Boric Acid
- Urease immobilized on an aminated polysulphone membrane – inhibition by boric acid
- Polyelectrolyte behaviour of poly(vinyl alcohol)-boric acid complexes
- Production of Crystalline Boric Acid through the Reaction of Colemanite Particles with Propionic Acid
- Crystallization of Boric Acid through Reactive Dissolution of Oxalic Acid Crystals in Aqueous Borax Solution
- Thermal analysis of cellulose treated with boric acid or ammonium phosphate in varied oxygen atmospheres
- The reaction of boric acid with wood in a polystyrene matrix
- Starch crosslinked with poly(vinyl alcohol) by boric acid
- Boric acid recovery using polymer filtration: Studies with alkyl monool, diol, and triol containing polyethylenimines
- Flame retardant synergism of GUP and boric acid by cone calorimetry
- Boric acid binding studies with diol containing polyethylenimines as determined by 11B NMR spectroscopy
- pH-controlled uphill transport of boric acid through a poly(vinyl alcohol) (PVA) membrane
- Effect of gel spinning accompanied with cross-linking using boric acid on the structure and properties of high-molecular-weight poly(vinyl alcohol) fiber
- Investigation of flame retardancy and physical–mechanical properties of zinc borate/boric acid polyester composites
- Sorption properties of wood impregnated with aqueous solution of boric acid and montan wax emulsion
- Effect of boric acid and heat treatment for the formation of poly(vinyl alcohol)/iodine complex films iodinated at solution before casting
- Effect of boric acid treatment method on the characteristics of poly(vinyl alcohol)/iodine polarizing film
- The effects of boric acid-induced oxidative stress on antioxidant enzymes and survivorship in Galleria mellonella
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