Brilliant green
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Clinical Pharmacology
Brilliant green solution has an antiseptic effect. It is a highly active and fast-acting antiseptic. Active against gram-positive bacteria. In the aquatic environment, it has a detrimental effect on the culture of Staphylococcus aureus.(Staphylococcus aureus) at a concentration of 1: 10,000,000, its phenol ratio is equal to 40,000 (phenol ratio is the ratio of the concentrations of phenol and the test antiseptic in which substances have the same antimicrobial effect, the phenol ratio is one of the common criteria for evaluating the activity of antiseptics). High sensitivity to brilliant green detects diphtheria stick(Corynebacterium diphtheriae).In the presence of organic substances, the antimicrobial activity decreases: when assessing the activity of this dye in a medium containing 10% serum, the phenol coefficient is 120 (0.3% of the value in an aqueous medium).
Indications
Fresh postoperative and post-traumatic scars, meybomit (barley), blepharitis, pyoderma, abrasions, cuts, skin integrity problems, erysipelas, folliculitis.
Composition
1 ml of alcohol solution contains bis- (p-diethylamino) triphenyl-anhydrocarbinol oxalate 10 mg
Brilliant green is marketed under different brands and generic names, and comes in different dosage forms:
Brand name | Manufacturer | Country | Dosage form |
---|---|---|---|
Brilliant green alcohol solution 1% | Lekker Ltd | Russia | solution |
Brilliant green alcohol solution 1% | PFK Obnovlenie | Russia | vials |
Brilliant green | PFK Obnovlenie | Russia | vials |
Brilliant green alcohol solution 1% | St. Petersburg pharmaceutical plant | Russia | solution |
Brilliant green | Ivanovo pharmaceutical factory | Russia | vials |
Brilliant green alcohol solution 1% | PFK Obnovlenie | Russia | bottle |
Brilliant green alcohol solution 1% | Samara pharmaceutical factory | Russia | solution |
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Dosage and Administration
Topically, applied to the damaged surface, capturing the surrounding healthy tissue.
Adverse reactions
After contact with the mucous membrane of the eye - burning, tearing.
Contraindications
Hypersensitivity
Drug interactions
Incompatible with disinfectant drugs containing active iodine, chlorine, alkali (including ammonia solution).
Pregnancy and Lactation
maybe
- Brand name: Brilliant green alcohol solution 1%
- Active ingredient: Brilliant green
- Dosage form: Solution for external use alcohol transparent, intensely green, with the smell of alcohol
- Manufacturer: Lekker Ltd.
- Country of Origin: Russia
Studies and clinical trials of Brilliant green (Click to expand)
- Removal of Brilliant Green Dye from Aqueous Solutions Using Home Made Activated Carbons
- Interaction of brilliant cresyl blue and methylene green with DNA studied by spectrophotometric and voltammetric methods
- Spectrophotometric determination of traces of iodide by liquid—liquid extraction of Brilliant Green—iodide ion pair
- Flow-injection determination of traces of formaldehyde by the Brilliant Green—sulphite reaction with spectrophotometric detection
- Spectrophotometric determination of antimony after extraction of Brilliant Green hexachloroantimonate(V) with microcrystalline 1,4-dichlorobenzene
- Studies on Brilliant Green and Solochrome Red B: I. The acid-base properties
- The use of redox reactions in the analysis of dyes and dye industry intermediates: III. An indirect determination of brilliant green with ceric sulfate
- Study of the system Os(IV)-chloride-brilliant green: Extraction-spectrophotometric determination of osmium
- The hydrolysis of brilliant green and some derivatives.: Part 3: The kinetics of the hydrolysis of some 2-substituted derivatives of brilliant green
- Process Studies on Laser Welding of Copper with Brilliant Green and Infrared Lasers
- Multiresidue method for the triphenylmethane dyes in fish: Malachite green, crystal (gentian) violet, and brilliant green
- Adsorption characteristics of the hazardous dye Brilliant Green on Saklıkent mud
- Photocatalyzed N-de-ethylation and degradation of Brilliant Green in TiO2 dispersions under UV irradiation
- Studies on the adsorption of Brilliant Green dye from aqueous solution onto low-cost NaOH treated saw dust
- Use of bagasse fly ash as an adsorbent for the removal of brilliant green dye from aqueous solution
- Applicability of waste materials—bottom ash and deoiled soya—as adsorbents for the removal and recovery of a hazardous dye, brilliant green
- Decoloration of aqueous Brilliant Green by using glow discharge electrolysis
- Adsorption characteristics of brilliant green dye on kaolin
- Sorption of Cr(VI) by Amberlite XAD-7 resin impregnated with brilliant green and its determination by quercetin as a selective spectrophotometric reagent
- Chemical and structural evaluation of activated carbon prepared from jute sticks for Brilliant Green dye removal from aqueous solution
- Studies on the treatment of brilliant green solution by combination microwave induced oxidation with CoFe2O4
- Flow-injection extraction-spectrophotometric determination of perchlorate with brilliant green
- Separation of rhenium by extraction with crown ethers and flow-injection extraction—spectrophotometric determination with Brilliant Green
- Dye-assisted chromatographic determination of aliphatic ketones and esters with brilliant green