Calcium chloride
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Clinical Pharmacology
A drug that compensates for the lack of calcium in the body. Calcium chloride has anti-inflammatory, anti-allergic, hemostatic effect. Calcium ions are involved in the transmission of nerve impulses, reducing skeletal and smooth muscles, in the functional activity of the myocardium, blood clotting, formation and preservation of the integrity of bone tissue.
Indications
As an additional tool in the treatment of allergic diseases (including serum sickness, urticaria, angioedema, hay fever) and allergic reactions to drugs. As an additional hemostatic agent for pulmonary, gastrointestinal, nasal, uterine bleeding. As an antidote for poisoning with magnesium salts, oxalic acid and its soluble salts, as well as soluble salts of fluoric acid.
Composition
calcium chloride - 100mg
Calcium chloride is marketed under different brands and generic names, and comes in different dosage forms:
Brand name | Manufacturer | Country | Dosage form |
---|---|---|---|
Calcium chloride | Dalkhimpharm | Russia | ampoules |
Calcium chloride | ampoules |
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Dosage and Administration
With the / in the introduction of a single dose of 0.5-1 mg. When ingested a single dose - 0.25-1.5 g. The frequency and duration of use depends on the evidence and the clinical situation.
Adverse reactions
Maybe: bradycardia; with the rapid introduction - ventricular fibrillation; with a / in the introduction - a sensation of heat in the mouth, and then in the whole body.
Contraindications
Tendency to thrombosis, pronounced atherosclerosis, hypercalcemia.
Drug interactions
Calcium chloride is incompatible with salts of lead, silver, monovalent mercury due to the formation of insoluble heavy metal chlorides and with sodium barbital, since as a result, the low soluble calcium salt of barbital is formed.
Calcium chloride with simultaneous use reduces the effect of calcium channel blockers. Under the influence of Kolestiramin calcium absorption from the gastrointestinal tract is reduced. With simultaneous use with quinidine may slow intraventricular conductivity and increase the toxicity of quinidine. During treatment with cardiac glycosides, parenteral administration of calcium chloride is not recommended, due to increased cardiotoxicity.
Special instructions
Do not enter p / to and / m. When calcium chloride gets under the skin or into muscle tissue, strong irritation develops with the formation of foci of necrosis.
- Tissue norepinephrine depletion as a mechanism for calcium chloride inhibition of gastric carcinogenesis in rats after treatment with N-methyl-N<′-nitro-N-nitrosoguanidine and sodium chloride
- Self-setting barrier membrane for guided tissue regeneration method: Initial evaluation of alginate membrane made with sodium alginate and calcium chloride aqueous solutions
- Calcium regulated chloride permeabilities in primary cultures of rabbit colonocytes
- Membrane depolarization in NRK fibroblasts by bradykinin is mediated by a calcium-dependent chloride conductance
- Intracellular chloride and calcium transients evoked by γ-aminobutyric acid and glycine in neurons of the rat inferior colliculus
- Experimental performance of the water/calcium chloride system in a heat transformer
- Performance study of a double-absorption water/calcium chloride heat transformer
- An Expected Calcium Carbido Borate Chloride: Ca9Cl8(BC2)2
- Corrosion inhibition of carbon steel in chloride solutions by blends of calcium gluconate and sodium benzoate
- Interdependence between sodium transport, external chloride, and sodium/calcium exchanger in the isolated skin of the Rana pipiens
- Vapor-Liquid Equilibrium of MTBE-Methanol, MTBE-Methanol-Calcium Chloride and MTBE-Methanol-Lithium Chloride Mixtures
- Preparation of mixtures of silicon oxynitride and silicon nitride by the reaction of calcium silicide with ammonium chloride
- Characteristics of water-calcium chloride and water-lithium bromide absorption heat pumps
- Electrochemical Preparation of Silicon and Its Alloys from Solid Oxides in Molten Calcium Chloride
- Electrochemical Preparation of Silicon and Its Alloys from Solid Oxides in Molten Calcium Chloride
- Calcium stearate–stearic acid as lubricants for rigid poly(vinyl chloride) (PVC). Capillary rheometer measurements and extrusion properties
- Stabilization of poly(vinyl chloride). VI. Synergetic effects of aminopolycarboxylates or nitrogen-containing agents with zinc stearate/calcium stearate soap
- Immobilized extractants: Selective transport of magnesium and calcium from a mixed chloride solution via a hollow fiber module
- Nanocomposites of poly(vinyl chloride) and nanometric calcium carbonate particles: Effects of chlorinated polyethylene on mechanical properties, morphology, and rheology
- Tin dioxide coated calcium carbonate as flame retardant for semirigid poly(vinyl chloride)
- Flame-retardant properties of magnesium hydroxystannate and strontium hydroxystannate coated calcium carbonate on soft poly(vinyl chloride)
- Physicochemical characterization of a pectin/calcium matrix containing a large fraction of calcium chloride: Implications for sigmoidal release characteristics
- Study on dry spinning and structure of low mole ratio complex of calcium chloride-polyamide 6
- A new permanent solution for the preservation of anatomic preparations, the Souchon solution of calcium chloride