Carbomer

Brand Santen

In stock 1797 Items

Available since: 2019-09-19

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Clinical Pharmacology

Oftagel contains carbomer, which is a high molecular weight carboxyvinylpolymer (polyacrylate). Carbomer increases the viscosity of the tear, forming a protective moisturizing film on the surface of the cornea, thickens the mucin and water layers of the tear film. Oftagel reduces the symptoms of irritation associated with dry eye syndrome, which includes compensatory tearing, itching, burning, foreign body sensation in the eye and visual fatigue.

Prolonged contact of the tear film with the cornea has a beneficial effect in reducing the secretion of the tear fluid. With simultaneous use of oftagel can prolong the absorption of other ophthalmic drugs.

Pharmacokinetics

Due to the relatively large size of the carbomer molecule, penetration through the cornea is unlikely.

Indications

Diseases accompanied by dry eye syndrome, manifested by compensatory tearing, itching, burning sensation, foreign body sensation in the eye:

Dry keratoconjunctivitis.
Irritation of the eyes (as a result of exposure to dust, smoke, while working on a computer - "office eye syndrome").
Insufficient tearing.
Stevens-Johnson syndrome.
Sjogren's disease.
Diseases of the eyelids, leading to insufficient contact of the cornea with a tear.

Restorative therapy after laser and surgical interventions on the cornea.

Composition

1g eye gel contains:

Active ingredients

Carbomer 974P 2.5 mg.

Excipients

Benzalkonium chloride (0.06 mg / 1 g), sorbitol, lysine monohydrate, sodium acetate, polyvinyl alcohol, water d / and.

Carbomer is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
Oftagel	Santen	France	gel
Vidisic®	Bausch and Lomb	USA	gel

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Dosage and Administration

Oftagel instilled 1 drop of 1-4 times / day, depending on the severity of symptoms.

Wash hands before use; before instillation of Othegel, head should be tilted back, pull the lower eyelid and put 1 drop of gel into the conjunctival sac between the lower eyelid and the eye.

Do not touch the eye and eyelid with the pipette tip. After using the drug, you must immediately close the bottle.

Adverse reactions

Local reactions: immediately after instillation, transient blurred vision, short-term burning sensation and local eye irritation are possible.

Contraindications

Hypersensitivity to the drug.

Drug interactions

Prolongs absorption of other eye preparations. If more than one type of eye drops is prescribed, they should be applied at intervals of at least 15 minutes, and Oftagel should always be instilled last.

Pregnancy and Lactation

There have been no adequate controlled studies of the use of the drug Oftagel in pregnant women.

The use of the drug during pregnancy and lactation is possible only on prescription.

Special instructions

Benzalkonium chloride, which is part of the drug, can be adsorbed in contact lenses. Therefore, before using Ofthegel, they should be removed and installed again 30 minutes after instillation of the drug.

If necessary, the appointment simultaneously with Oftagel other eye drops. Oftagel should be instilled last with an interval of at least 15 minutes.

It should be borne in mind that the bottle with the drug is intended for use by only one person.

Influence on ability to drive motor transport and control mechanisms

Eye Gel Eye ofgel can cause a short-term decrease in visual acuity. Before you start driving a car or working with mechanical devices, you must wait until visual acuity is fully restored.

Studies and clinical trials of Carbomer (Click to expand)