Contractubex
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Clinical Pharmacology
Contractubex - a combined drug, the action of which is due to the properties of its constituent components.
It turns out fibrinolytic anti-inflammatory (due to the presence of onion extract), antithrombotic (due to the presence of heparin), and keratolytic action (due to the presence of allantoin).
Stimulates cell regeneration without hyperplasia.
Inhibits the proliferation of colloidal fibroblasts.
Indications
- Hypertrophic and keloid scars that occur after surgery, amputations, burns and injuries;
- Ankylosis of the joints;
- Dupuytren's contracture;
- Traumatic tendon contractions;
- Stretch marks after pregnancy
- Atrophic scars
- Prevention of the formation of pathological scars in the postoperative period or after injury.
Composition
100 g:
- Onion extract 10 g
- Heparin 5000 IU
- Allantoin 1 g
Excipients: Sorbic acid, Methyl-4-hydroxybenzoate, Perfume, DROM 2700, Xanthan, Polyethylene glycol 200, purified water.
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Dosage and Administration
Can be used in children, pregnant women, as well as during lactation.
The consumption of the drug in one application on average 0.5 cm. Gel on a scar surface of 20-25 cm². Apply 2-3 times a day, slightly rubbing into the scar tissue. The course of treatment for fresh scars averages 4 weeks.
When old, tight scars at night impose an occlusive dressing with gel. The course of treatment is an average of 3-6 months. With Dupuytren's contracture, the course of treatment is an average of 12 months.
For prophylaxis, the phase after wound epithelization is used.
Adverse reactions
Seldom: local skin reactions.
Drug interactions
Due to the lack of systemic absorption of the drug, its use in combination with other drugs is possible.
The presence of two types of packages of 20 g and 50 g allows patients with a small scar, or for the first time using the drug, to purchase a 20 g tube.
The need for long-term use of the drug due to the slow recovery of physiological processes in the skin itself, requiring several months, and the composition based on high-quality natural components allows the use of CONTRACTUBEX for as long as necessary.
Pregnancy and Lactation
The action of the drug Contractubex during pregnancy and lactation has not been studied.
Special instructions
To enhance the effect of the drug applied to pre-steamed skin. Perhaps its use in combination with physiotherapy activities.
When treating fresh scars, ultraviolet radiation, exposure to cold and intense massage should be avoided.
- Brand name: Contractubex
- Active ingredient: Allantoin, Heparin Sodium, Onion Bulbs Extract
- Dosage form: Gel for external use.
- Manufacturer: Merz
- Country of Origin: Germany
Studies and clinical trials of Contractubex (Click to expand)
- Effects of Contractubex on the Prevention of Postoperative Peritoneal Adhesion
- Comparison of the Effects of Contractubex® Gel and Benzothiazole after Topical Application in an Experimental Model of Epidural Fibrosis in Rats
- The Effects of Topical Agent (Kelo-Cote or Contractubex) Massage on the Thickness of Post-Burn Scar Tissue Formed in Rats