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Combined drug, whose action is determined by the effects of its constituent vitamins and coenzymes, as well as their synergistic effect.
Cocarboxylase (coenzyme) catalyzes carboxylation and decarboxylation of α-keto acids, participates in carbohydrate metabolism.
Through participation in the pentose cycle indirectly contributes to the synthesis of nucleic acids, proteins, lipids. It contributes to the correction of metabolic acidosis and cell hypoxia, as well as other metabolic disorders (insufficiency of the liver, kidneys, CVS, chronic intoxication).
Riboflavin (Vitamin B2) as a coenzyme flavinprotein involved in the regulation of redox reactions (carbohydrate, protein and fat metabolism). It plays an important role in the synthesis of hemoglobin, maintaining the normal visual function of the eye and the state of the mucous membranes and skin.
Thioctic acid is involved in the oxidative decarboxylation of pyruvic acid and α-keto acids, in the regulation of lipid and carbohydrate metabolism, plays an important role in the process of energy formation in the body. Thioctic acid has a hepatoprotective effect, improves the detoxification of the liver, protects against the effects of exo- and endotoxins.
Corilip-Neo improves tissue metabolism in various physiological and pathological conditions that need to be corrected by cofactors and substrates.
For prophylactic and therapeutic purposes in the treatment of various pathological conditions in children, such as:
- chronic tissue hypoxia;
- reduced immunity;
- bacterial and viral infections, incl. acute intestinal infections;
- chronic somatic diseases;
- chronic intoxication;
- malnutrition (hypotrophy) in children.
|cocarboxylase hydrochloride (cocarboxylase)||12.5 mg|
|lipoic acid (thioctic acid)||6 mg|
|excipients: solid fat (fatty acids glycerides) - 930.5 mg||
Corilip® is marketed under different brands and generic names, and comes in different dosage forms:
|Brand name||Manufacturer||Country||Dosage form|
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Dosage and Administration
The drug is used rectally. Having released from packing, enter the suppository into the anus after preliminary emptying of the intestines.
Suppositories prescribed to children under 1 year of 1 suppository per day.
Duration of treatment is 10 days. The total duration of treatment is 3-4 courses with an interval of 20 days (3-4 months).
Allergic reactions are possible - urticaria, pruritus, bronchospasm, dyspepsia. If adverse reactions occur, stop taking the drug and consult a doctor.
- hypersensitivity reactions to the components that make up the drug;
- inflammation or bleeding in the rectum (contraindication associated with the route of administration).
Negative interaction was not observed. The drug can be used in complex therapy.
Along with the clinical condition, the criteria for the duration of treatment are cytochemical indicators of the activity of peripheral blood leukocyte enzymes (succinate dehydrogenase and glycerophosphate dehydrogenase).
Cases of overdose are not described.
- Brand name: Corilip-NEO
- Active ingredient: Cocarboxylase, Riboflavin, Thioctic Acid
- Dosage form: Rectal suppositories, yellow, torpedo-shaped with possible splashes of orange-yellow color.
- Manufacturer: Altfarm
- Country of Origin: Russia