Buy Dexalgin granules 25 mg sachets 10 pcs

Dexketoprofen

In stock 970 Items

Available since: 2019-09-19

Dosage form

pills
solution
ampoules
granules

Brand & Manufacturer

Package Size

25 mg sachets 10 pcs

$26.94

Quantity

All payments are SSL encrypted
Full Refund if you haven't received your order
International shipping to the USA, UK and Europe

Clinical Pharmacology

pharmachologic effect

NSAIDs. It has anti-inflammatory, analgesic and antipyretic effects. The mechanism of action is based on the inhibition of the synthesis of prostaglandins due to the suppression of COX.

Analgesic effect occurs 30 minutes after administration, the duration of action - 4-6 hours.

Pharmacokinetics

After taking the drug inside Cmax dexketoprofen in humans is achieved on average after 30 minutes (15-60 minutes). Plasma protein binding - 99%. Average Vd - less than 0.25 l / kg. T1 / 2 is 1.65 hours. It is metabolized. Excreted mainly by the kidneys as metabolites.

Indications

Mild and moderate intensity pain syndrome in the following diseases and conditions: acute and chronic inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, spondylitis, arthrosis, osteochondrosis); dysmenorrhea; toothache.

Composition

1 pack

Dexketoprofen trometamol 36.9 mg, which corresponds to the content of dexketoprofen 25 mg.

Excipients: ammonium glycyrrhizinate - 2 mg, neohesperidin dihydrochalkon - 1.5 mg, quinoline yellow dye (E104) - 1.2 mg, lemon flavoring - 40 mg, sucrose with colloidal silicon dioxide (500: 1) - 2418 mg.

Dexketoprofen is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
Dexalgin	Berlin-Chemie/Menarini	Germany	granules
Flamadex	Sotex	Russia	pills
			pills
Ketodexal	K.O.Romparm Company S.R.L	Romania	solution
Dexalgin	Berlin-Chemie/Menarini	Germany	ampoules
Flamadex	Sotex	Russia	solution
Dexalgin	Berlin-Chemie/Menarini	Germany	pills

No customer reviews for the moment.

Write your review

Dosage and Administration

For oral use. The average recommended single dose is 12.5 mg - 1-6 times / day every 4-6 hours as needed, or 25 mg 1-3 times / day every 8 hours.

The maximum daily dose is 75 mg. Duration of use - no more than 3-5 days.

For patients with impaired liver or kidney function, the elderly, the initial dose is not more than 50 mg / day.

Adverse reactions

On the part of the digestive system: heartburn, abdominal pain; rarely - erosive and ulcerative lesions of the gastrointestinal tract.

From the nervous system: headaches, dizziness, nervousness, sleep disturbance, paresthesia.

Since the cardiovascular system: heartbeat, increased blood pressure.

Allergic reactions: skin rash, bronchospasm.

Others: chills, swelling of limbs, photosensitization; rarely - a change in the pattern of peripheral blood, renal dysfunction.

Contraindications

Peptic ulcer and duodenal ulcer, gastrointestinal bleeding, active bleeding of various origins, increased bleeding, anticoagulant therapy, Crohn's disease, ulcerative colitis, asthma (including history), severe heart failure, renal failure, hepatic insufficiency, pregnancy, lactation, hypersensitivity to dexketoprofen or other NSAIDs.

Drug interactions

With the simultaneous use of dexketoprofen with other NSAIDs may increase the risk of side effects.

With simultaneous use with lithium preparations may increase the concentration of the latter in the blood plasma.

Use dexketoprofen with caution in less than 24 hours before the start of application or after the end of therapy with methotrexate, since the plasma concentration of the latter (and, consequently, toxicity) may increase.

Selected cases of bleeding with the simultaneous use of NSAIDs and anticoagulants.

Special instructions

Care should be taken when prescribing the drug to elderly patients, patients with allergic reactions, systemic connective tissue diseases and patients with impaired blood formation.

Patients should be informed that in the event of side effects, as well as in the absence of clinical effect, it is necessary to inform the attending physician within 3-5 days of treatment.

Special care is required with simultaneous use of dexketoprofen with phenytoin, sulfonamides, and drugs that reduce blood clotting.

Influence on ability to drive motor transport and control mechanisms

Since dexketoprofen can cause a decrease in the ability to concentrate, it should be used with caution in patients engaged in potentially hazardous activities that require increased attention and quickness of psychomotor reactions.