Dexpanthenol

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Available since: 2019-09-19

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Clinical Pharmacology

A drug that improves tissue regeneration for external use.

Dexpanthenol is a derivative of pantothenic acid, which is a water-soluble vitamin B required as an integral part of coenzyme A for carbohydrate, protein and fat metabolism. It plays an important role in the processes of acetylation during gluconeogenesis, the release of energy from carbohydrates, the synthesis and cleavage of fatty acids, the synthesis of sterols and steroid hormones, acetylcholine.

Pantothenic acid is necessary to maintain the normal function of the epithelium, an increase in the need for it is noted when the skin or tissue is damaged, in this case, local deficiency of pantothenic acid can be replenished by topical application of D-Panthenol ointment.

Stimulates skin regeneration, normalizes cell metabolism, increases the strength of collagen fibers.

It has a regenerating, weak anti-inflammatory effect, nourishes and softens the skin.

Auxiliary substances improve the therapeutic properties of the ointment.

Indications

In children, diaper dermatitis, scratches, minor irritations after exposure to the sun, ultraviolet and X-rays, for the treatment and prevention of diaper rash.
Cracks and inflammation of the nipples in nursing mothers.
Violations of the integrity of the skin caused by mechanical, chemical, temperature factors or after surgery (burns of various origins (including sunburn), scratches, abrasions, wounds, bedsores, poorly healing skin grafts, aseptic postoperative wounds).
Inflammation of the skin, dermatitis, boils, trophic ulcers of the lower extremities, skin care around the tracheostomy, gastrostomy, colostomy.
Treatment and prevention of the effects of adverse effects on the skin of environmental factors (including cold, wind, humidity).

Composition

Ointment for external use of 5%.

1 g ointment contains:

Active ingredient: dexpanthenol - 50 mg.

Excipients: phenonip - 4 mg, lanolin - 160 mg, beeswax white - 50 mg, white soft paraffin - 210.8 mg, dimethicone - 5 mg, LANETTE SX emulsifier - 20 mg, propylene glycol - 20 mg, butyl hydroxyanisol - 0.1 mg , butylhydroxytoluene - 0.1 mg, decamethylcyclopentasiloxane - 20 mg, magnesium sulfate heptahydrate - 5 mg, Protein B - 295 mg, purified water - 160 mg.

Dexpanthenol is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
D-Panthenol			ointment
D-Panthenol			cream
			ointment
Vitateka panthenol			spray
D-panthenol-Nizhpharm			cream
Dexpanthenol	Vertex	Russia	ointment
Bepanten	Grenzah Products GmbH	Germany	ointment
Bepanten	Grenzah Products GmbH	Germany	cream
Panthenol-Teva	Teva	Israel	Other
Dexpanthenol	Tatkhimpharmpreparaty	Russia	ointment
Panthenol-Teva	Teva	Israel	ointment
Panthenol	Chauvin Ankerpharm	Germany	spray
Panthenol	Avanta	Russia	cream
D-Panthenol	Jadran-Galensky Laboratories ao	Croatia	spray
Panthenol	IPOC Cosmetics	Russia	cream
Panthenol (Pharmstandard	Pharmstandard	Russia	spray can
D-Panthenol	Jadran-Galensky Laboratories ao	Croatia	cream
D-Panthenol	Jadran-Galensky Laboratories ao	Croatia	ointment
Pantoderm	Akrikhin	Russia	ointment
Korneregel	Valeant	Russia	gel