Buy Enzaprost-F ampoules 5 mg/ml, 1 ml, 5 pcs

Dinoprost

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Clinical Pharmacology

Enzaprost-F - a drug that increases the tone and contractile activity of the myometrium - stimulates labor activity, expands the cervix.

Indications

Termination of pregnancy with intrauterine fetal death in the I-II trimester, in the case of severe pathology of the fetus (anencephaly, hydrocephalus, amelia);
initiation of labor in connection with fetal fetal death (late pregnancy), premature discharge of water, primary birth weakness, placental phase of labor;
stimulation and stimulation of labor in artificially induced labor.

Composition

1 ampoule contains:

Active substance: dinoprost 5 mg;

Excipients:sodium acetate trihydrate, water d / and.

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Dosage and Administration

IV, extra- or intra-amnally. To terminate pregnancy, extraamnially injected into the uterine cavity (through a catheter): during pregnancy from 0 to 6 weeks - 3-5 mg, with terms from 7 to 14 weeks - 5 mg, and in 5-6 hours another 5-10 mg. In pregnancy from 15 to 28 weeks, 25 mg is administered predominantly intraamnially (after sucking off several milliliters of amniotic fluid and the absence of blood in it), in the absence of effect, again after 8-12 hours. For induction of labor, intravenously in a dose and with speed, depending on the specific clinical situation and the response to the therapy; As a rule, the total dose is 1–5 mg and the speed of administration is 9–15 mcg / min.

Adverse reactions

Since the cardiovascular system:peripheral vascular spasms; bradycardia; temporary increase or decrease in blood pressure; tachycardia; second-degree atrioventricular block; ventricular arrhythmia; feeling of pressure or pain in the sternum; development and aggravation of heart failure.

On the part of the respiratory system:bronchospasm; lung hyperventilation.

From the side of the central nervous system:diplopia; miosis; paresthesias; dizziness; general weakness; euphoria.

From the digestive tract:hiccups, intestinal paralysis.

From the genitourinary system:urination disorders (urinary incontinence, dysuria, urinary retention, atony or hypertonicity of the bladder); hematuria; painful contractions associated with increased uterine contractility.

Other:burning eyes; pain in the legs, back and shoulders; increase in the number of leukocytes.

Contraindications

Broncho-obstructive syndrome, ulcerative colitis (exacerbation and remission), sickle cell anemia, glaucoma, arterial hypertension (160/100 mm Hg and above), epilepsy, scarring in the uterus (cesarean section, removal of myomas in history, etc. .), congenital malformations of the uterus, uterine fibroids, heart failure, active pulmonary tuberculosis, severe impaired liver function.