Buy Driptane pills 5 mg, 30 pcs
  • Buy Driptane pills 5 mg, 30 pcs

Driptane® [Oxybutynin]

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1515 Items
2019-09-19
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$46.25
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Clinical Pharmacology

Antispasmodic, myotropic. Driptanee relaxes the detrusor (bladder contraction muscle). It has a direct antispasmodic myotropic and m-anticholinergic action. Increases the capacity of the bladder, reduces the frequency of detrusor contractions, restrains the urge to urinate.

Indications

  • urinary incontinence associated with instability of bladder function, impaired or as a result of neurogenic disorders (hyperreflex detrusor), for example, in case of widespread sclerosis or spina bifida, or idiopathic dysfunction of the detrusor (motor incontinence);
  • Nocturnal enuresis in children over 5 years old.

Composition

1 tablet contains:
active substance: oxybutynin hydrochloride 5 mg
Excipients: microcrystalline cellulose, calcium stearate, anhydrous lactose.

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Driptane® [Oxybutynin]

Dosage and Administration

Driptanee is taken orally. Adults - 5 mg 2-3 times a day, children and elderly patients - 5 mg 2 times a day.

Adverse reactions

Nausea, constipation, diarrhea, abdominal discomfort, urinary retention, drowsiness or insomnia, general weakness, headache, dizziness, arrhythmia, blurred vision (mydriasis, accommodation paralysis), increased intraocular pressure, decreased sweating, dry mouth, impotence, allergic reactions.

Contraindications

  • hypersensitivity to Driptanee components;
  • angle-closure glaucoma;
  • obstruction of the gastrointestinal tract, intestinal atony, expansion of the colon, ulcerative colitis;
  • myasthenia gravis;
  • obstructive uropathy;
  • bleeding;
  • breastfeeding period;
  • children's age up to 5 years.

Special instructions

Caution is needed in violation of the functions of the kidneys and liver, hyperthyroidism, coronary artery disease, heart failure, arrhythmias, hypertension, prostate adenoma, hernia of the esophageal orifice of the diaphragm.

Overdosage

Symptoms: CNS agitation (anxiety, tremor, increased nervous irritability, convulsions, delirium, hallucinations), fever, nausea, vomiting, tachycardia, lowering blood pressure, respiratory failure, paralysis, coma.

Treatment: one should maintain breathing, induce vomiting or carry out gastric lavage, administer activated charcoal and saline laxative. For regression of symptoms of anticholinergic intoxication, cholinesterase blockers (physostigmine) are used. When expressed anxiety or agitation - IV the introduction of 10 mg of diazepam. With tachycardia - propranolol (w / w).

Studies and clinical trials of Oxybutynin (Click to expand)
  1. Fibrinolytische Behandlung von akuten und subakuten Thrombosen der tiefen Venen des Schultergürtels
  2. Treatment of overactive bladder with modified intravesical oxybutynin chloride
  3. Equilibrium studies on enantioselective extraction of oxybutynin enantiomers by hydrophilic β-cyclodextrin derivatives
  4. Metabolism of oxybutynin: Establishment of desethyloxybutynin and oxybutynin N-oxide formation in rat liver preparations using deuterium substitution and gas chromatographic mass spectrometric analysis
  5. A Practical Synthesis of (S)-Oxybutynin.
  6. Catalytic Asymmetric Synthesis of (S)-Oxybutynin and a Versatile Intermediate for Antimuscarinic Agents.
  7. A semiparametric deconvolution model to establish in vivo–in vitro correlation applied to OROS oxybutynin
  8. Treatment of micturitional disorders in the Shy-Drager syndrome with oxybutynin chloride and self intermittent catheterization
  9. Effect of oxybutynin on reflex micturition in the decerebrate dog as determined by urodynamic evaluation
  10. Relaxation of intestinal bladders by intravesical oxybutynin chloride
  11. Epistaxis as a side effect of oxybutynin in children: Report of two cases
  12. Intravesical oxybutynin in patients with posterior rhizotomies and sacral anterior root stimulators
  13. Systemic oxybutynin decreases afferent activity of the pelvic nerve of the rat: New insights into the working mechanism of antimuscarinics
  14. The effect of intravesical oxybutynin on the ice water test and on electrical perception thresholds in patients with neurogenic detrusor overactivity
  15. High-performance liquid chromatographic preparation of oxybutynin enantiomers on a chiral stationary phase
  16. Reproductive toxicity studies with oxybutynin hydrochloride
  17. New transdermal bioadhesive film containing oxybutynin: In vitro permeation across rabbit ear skin
  18. Oxybutynin permeation in skin: The influence of drug and solvent activity
  19. Design, synthesis and activity of novel derivatives of Oxybutynin and Tolterodine
  20. Patient satisfaction with transdermal oxybutynin: Interim results from the matrix study
  21. LBOVI-A-1Does prior treatment for overactive bladder affect quality of life outcomes with transdermal oxybutynin? Results from the MATRIX study
  22. Adsorptive stripping voltammetric behavior and determination of anticholinergic agent oxybutynin chloride on a mercury electrode
  23. The investigation of the interaction between oxybutynin hydrochloride and bovine serum albumin by spectroscopic methods
  24. Rapid and selective UV spectrophotometric and RP-HPLC methods for dissolution studies of oxybutynin immediate-release and controlled-release formulations
  25. Catalytic asymmetric synthesis of (S)-oxybutynin and a versatile intermediate for antimuscarinic agents

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