Erythromycin

Brand Tatkhimpharmpreparaty

In stock 809 Items

Available since: 2019-09-19

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Clinical Pharmacology

Erythromycin is an macrolide antibiotic. Acts bacteriostatic. Spectrum of experience; ., Treponema pallidum, Legionella pneumophila).
Erythromycin resistant most gram-negative bacteria (Escherichia coli, Shigella, Salmonella spp.), mycobacteria, small and medium-sized viruses, fungi.
Erythromycin is better tolerated by patients than penicillins, and can be used in allergies to penicillins. The resistance of microorganisms to the drug develops rapidly.

Indications

Eye infections caused by susceptible microorganisms:

conjunctivitis (including in newborns),
ophthalmic neonatal,
bacterial blepharitis,
blepharoconjunctivitis,
keratitis
maithomite (barley),
chlamydia
trachoma.

Composition

1 g ointment contains

Active substances: erythromycin (in terms of the active substance) - 10,000 U

Auxiliary components: anhydrous lanolin - 0.4 g, sodium disulfite - 0.0001 g, special petroleum jelly - up to 1 g

Erythromycin is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
Erythromycin ointment 10000 U/g	Tatkhimpharmpreparaty	Russia	ointment
Erythromycin	Biosynthesis	Russia	ointment

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Dosage and Administration

Erythromycin ointment is laid in the lower eyelid three times a day, in the treatment of trachoma up to 5 times a day. The duration of the course of therapy depends on the severity and form of the disease, but should not exceed 2 weeks.

Treatment of erythromycin trachoma must be combined with the opening of purulent follicles. When the process of inflammation subsides, the drug is used three times a day. The course of treatment of trachoma should not exceed three months.

Adverse reactions

Allergic reactions and irritation (redness, itching) are possible. With prolonged use, a secondary infection caused by microorganisms resistant to erythromycin can develop.

Contraindications

severe violations of the liver;
hypersensitivity.

Drug interactions

Erythromycin is an antagonist of lincomycin, clindamycin, chloramphenicol. Able to reduce the bactericidal effect of beta-lactam antibacterial agents (penicillins, cephalosporins, carbopenems).

The simultaneous use of external medicinal forms of erythromycin and abrasive substances that cause skin irritation, or with agents that cause peeling of the skin, a cumulative irritant or drying effect.

Pregnancy and Lactation

There is not enough clinical experience with the use of erythromycin ointment during pregnancy, lactation and in infants. Therefore, drug treatment is possible only in cases where the expected effect exceeds the risk of possible side effects.

Special instructions

Erythromycin can be prescribed for penicillin allergy.
The drug is prescribed with caution in violations of the liver and / or kidneys.
Erythromycin is not recommended to drink milk and dairy products.
Erythromycin crosses the placenta, is excreted in breast milk, therefore, when prescribing the drug during periods of pregnancy and lactation, the estimated benefits to the mother and the potential risk to the fetus should be assessed.

To prevent neonatal ophthalmia, it is not recommended to wash the eye ointment from the eye. In children whose mothers have pronounced gonorrhea, erythromycin is recommended to be used simultaneously with penicillin G (aqueous) solution for parenteral administration.