Ethinyl estradiol, Levonorgestrel

For oral use. pills should be taken in the order indicated on the packaging (blister), every day at about the same time, with a small amount of water. Take one tablet per day continuously for 21 days. Taking the pills from the next pack begins after a 7-day break in taking the pills, during which withdrawal bleeding usually occurs. Menstrual-like bleeding usually starts on the 2nd or 3rd day after taking the last pill and may not end before taking the pills from a new pack.

How to start taking the drug Trikvilar^®

In the absence of taking any hormonal contraceptive drugs in the previous month. Trikvilar drug intake^® Begins on the 1st day of the menstrual cycle (i.e., on the first day of the menstrual bleeding). It is allowed to start taking on the 2–5th day of the menstrual cycle, but in this case it is recommended to additionally use a barrier method of contraception during the first 7 days of taking the pills from the first package.

When switching from other COCs, vaginal ring or contraceptive patch. It is preferable to start taking the drug Trikvilar^® the next day after taking the last active tablet from the previous package, but in no case later than the next day after the usual 7-day break (for drugs containing 21 pills) or after taking the last inactive tablet (for drugs containing 28 pills. packaged). Trikvilar drug intake^® should begin on the day the vaginal ring or patch is removed, but no later than the day when a new ring is to be inserted or a new patch is pasted.

When switching from contraceptive preparations containing only gestagens («mini drank», injectable forms, implant), or with a progestogen-releasing intrauterine contraceptive (Mirena^®). A woman can switch from a “mini-drink” to Triquilar^®on any day (without a break), from the implant or intrauterine contraceptive with the progestogen - on the day of its removal, from the injection form - from the day when the next injection should be made. In all cases, you must use an additional barrier method of contraception during the first 7 days of taking pills.

After abortion in the first trimester of pregnancy. A woman can start taking the drug immediately. Subject to this condition, the woman does not need additional contraceptive protection.

After childbirth or abortion in the II trimester of pregnancy. It is recommended to start taking the drug on the 21-28th day after birth, if the woman is not breastfeeding, or after an abortion in the second trimester of pregnancy. If the reception is started later, you must use an additional barrier method of contraception during the first 7 days of taking the pills. However, during sexual intercourse, before starting the drug, Triquilar^® pregnancy should be excluded or it is necessary to wait for the first menstruation.

Taking missed pills

If the delay in taking the drug was less than 12 hours, contraceptive protection is not reduced. A woman should take a pill as soon as possible, the next one is taken at the usual time.

If the delay in taking the pills is more than 12 hours, contraceptive protection can be reduced. The more pills are missed, and the closer the pass to the 7-day break in taking pills, the greater the likelihood of pregnancy. In this case, you can follow the following two basic rules:

- the drug should never be interrupted for more than 7 days;

- 7 days of continuous pills are required to achieve adequate suppression of the hypothalamic-pituitary-ovarian regulation.

Accordingly, the following recommendations can be given:

The first week of taking the drug. A woman should take the last missed pill; as soon as possible, as soon as he remembers (even if it means taking two pills at the same time).The next pill is taken at the usual time. Additionally, a barrier method of contraception (for example, a condom) should be used within the next 7 days. If sexual intercourse took place during the week before the pill is missed, the likelihood of pregnancy must be considered.

The second week of taking the drug. A woman should take the last missed pill as soon as she remembers (even if it means taking two pills at the same time). The next pill is taken at the usual time. Provided that the woman took the pills correctly within 7 days preceding the first missed pill, there is no need to use additional contraceptive measures. Otherwise, as well as skipping two or more pills, you must additionally use barrier methods of contraception (for example, a condom) for 7 days.

The third week of taking the drug. The risk of reducing the reliability is inevitable due to the upcoming break in taking pills. A woman should strictly adhere to one of the following two options. At the same time, if in the 7 days preceding the first missed pill, all the pills were taken correctly, there is no need to use additional contraceptive methods:

1. A woman should take the last missed pill as soon as possible, as soon as she remembers (even if it means taking two pills at the same time). The following pills are taken at the usual time, until the pills from the current packaging run out. Taking the pills from the next pack should start right away. Withdrawal bleeding is unlikely until the pills from the second package run out, but there may be bleeding of varying degrees of intensity (from lightening to breakthrough) while taking the pills.

2. A woman can also stop taking pills from the current pack. She should then take a break for 7 days, including the day she misses the pills, and then start taking the pills from the new pack. If a woman misses taking pills, and then during a break in reception she has no withdrawal bleeding, it is necessary to exclude pregnancy.

Recommendations for gastrointestinal disorders

If the woman had vomiting or diarrhea within 3-4 hours after taking the pills, the absorption may be incomplete and additional contraceptive measures should be taken. In these cases, you should focus on the recommendations when skipping pills.

Change the day of the onset of menstrual bleeding

In order to delay the onset of menstrual bleeding, a woman must continue taking the drug using the last 10 table. (numbered from 12 to 21) from another package of Triquilar^®without interrupting reception. Thus, the cycle can be extended for up to 10 days until the end of the second package. While taking the drug from the second package, a woman may experience spotting or breakthrough uterine bleeding. Regular intake of the drug Triquilar^® then resumes after the usual 7-day break in taking pills.

In order to postpone the day of the onset of menstrual bleeding to another day of the week, the woman should reduce the next break in the pill for the desired number of days. The shorter the interval, the higher the risk that she will not have withdrawal bleeding and there will be spotting or breakthrough bleeding while taking the pills from the second package (just as if she would like to delay the onset of menstrual bleeding).

Additional information for specific patient groups

Kids and teens

Drug Triquilar^® contraindicated to establish ovulatory cycles.

Postmenopausal patients

Not applicable. Drug Triquilar^® Prototype after menopause.

Patients with hepatic impairment

Drug Triquilar^® contraindicated in women with severe liver disease, as long as the indicators of liver function do not come back to normal.

Patients with disorders of the kidneys. Drug Triquilar^® not specifically studied in patients with impaired renal disease. The available data do not imply correction of the dosage regimen in such patients.

Trikvilar can not be used during pregnancy and during lactation.

When skipping the drug Triquilar over 12 hours, you must take the next pill as quickly as possible and use additional methods of contraception until the end of the cycle. The effectiveness of the drug is reduced while taking drugs that activate the enzyme function of the liver, vomiting, diarrhea. Triquilar should be withdrawn during prolonged immobilization and 6 weeks before the planned surgical intervention.
It is not recommended to prescribe Triquilar to smokers over 35 years old. Women younger than 18 and older than 35-40 years are recommended three-phase low-dose drugs. For therapeutic and prophylactic purposes it is advisable to use monophasic drugs. The frequency and severity of side effects depends on the doses and ratios of the active substances that make up each preparation.

Symptoms that may occur during overdose: nausea, vomiting, bleeding from the genital tract.
In case of overdose, consult a doctor.