Fenkarol® [Quifenadine]
Olainfarm
575 Items
2019-09-19
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Clinical Pharmacology
Fenkarol - antiallergic, antihistamine. Blocks histamine H1 receptors. It activates diamine oxidase, an enzyme that inactivates histamine, and reduces the content of histamine in the tissues. Reduces the hypotensive effect of histamine, the effect on vascular permeability and the spasmogenic effect on the smooth muscles of the bronchi and intestines It has a slight m-anticholinergic activity. No pronounced inhibitory effect on the central nervous system.
Indications
- Pollinosis.
- Acute and chronic urticaria.
- Swelling Kwinke.
- Allergic rhinitis.
- Dermatosis (eczema, neurodermatitis, pruritus, etc.).
Composition
1 tablet contains: Hifenadina hydrochloride 25 mg.
Excipients: sugar, potato starch, calcium stearate.
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Dosage and Administration
The drug should be taken orally, after meals. The course of treatment for adults - 10-20 days, if necessary - again. Duration of treatment for children 10-15 days.
Recommended dosages: for adults - 25-50 mg 3-4 times per day (maximum daily dose - 200 mg); children from 2 to 3 years - 5 mg 2-3 times a day; children 3-7 years -10 mg 2 times a day; Children 7-12 years old - 10-15 mg 2-3 times a day.
Adverse reactions
On the part of the digestive system: dryness of the oral mucosa, nausea, vomiting.
CNS: drowsiness, headache.
Other: allergic reactions.
Contraindications
- Individual intolerance to the drug.
- Pregnancy.
- Lactation period.
Drug interactions
Does not enhance the inhibitory effect of alcohol and hypnotic drugs on the central nervous system. Possessing weak M-anticholinergic properties, it can decrease the motility of the gastrointestinal tract and increases the absorption of slowly absorbed drugs (for example, indirect anticoagulants - coumarins).
Pregnancy and Lactation
Contraindicated.
Special instructions
The absence of a pronounced anticholinergic effect makes it possible to prescribe to patients that antihistamines with anticholinergic activity are contraindicated.
The impact on the ability to drive vehicles and control mechanisms: persons whose profession requires a quick mental and motor response should first be determined (by short-term assignment) whether the drug does not have a sedative effect.
Overdosage
Symptoms: dry mucous membranes, headache, vomiting, abdominal pain and other dyspeptic symptoms.
Treatment: symptomatic. It is necessary to wash the stomach, take activated charcoal, immediately consult a doctor.
- Brand name: Fenkarol pills
- Active ingredient: Quifenadine
- Dosage form: Pills.
- Manufacturer: Olainfarm
- Country of Origin: Latvia
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