Fluocinolone acetonide

Brand Nizhpharm

In stock 908 Items

Available since: 2019-09-19

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Clinical Pharmacology

Glucocorticosteroid for external use. It has anti-inflammatory, anti-allergic, anti-exudative and antipruritic action. Reduces manifestations and eliminates inflammatory skin reaction.

Suggested use

Topically. A small amount of the drug is applied 2-4 times a day and lightly rubbed onto the skin previously cleaned with a tampon moistened with an antiseptic liquid. If necessary, you can apply an occlusive dressing, leaving it on the affected surface for up to 3-4 days. It is not allowed to apply under the dressing more than 2 grams per day. The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease up to 25 days. Ointment is preferable to use with dry forms of dermatosis.

Indications

Eczema, atopic dermatitis, simple chronic lichen (limited neurodermatitis), toksidermiya, simple allergic dermatitis, seborrheic dermatitis, pruritus, urticaria, scratching, diaper rash, erythema multiforme, psoriasis (exudative form); lichen planus, discoid lupus erythematosus, dyshidrosis of the hands, otitis externa, first degree burns, insect bites.

Composition

1 g of ointment contains: active ingredient: fluocinolone acetonide (sinaflan) - 0.25 mg, excipients: propylene glycol - 49.75 mg, ceresin - 50.00 mg, lanolin - 50.00 mg, petroleum jelly - up to 1.0 g .

Fluocinolone acetonide is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
Sinaflan®	Nizhpharm	Russia	ointment
Flucinar®	Elfa Pharmaceutical Plant	Poland	gel
Flucinar®	Elfa Pharmaceutical Plant	Poland	ointment

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Dosage and Administration

Adverse reactions

Perhaps the development of secondary infectious skin lesions and atrophic changes in it (burning, itching, dry skin, steroid acne, folliculitis). With prolonged use - hypertrichosis, alopecia, especially in women, secondary immunodeficiency (exacerbation of chronic infectious diseases, generalization of infectious process, the development of opportunistic infections); skin atrophy, local hirsutism, telangiectasia, purpura, pigmentation disorders. When applied to extensive surfaces, systemic manifestations are possible (gastritis, "steroid" gastric ulcer, adrenal insufficiency, Itsenko-Cushing's syndrome, "steroid" diabetes, slow reparative processes).

Contraindications

Hypersensitivity to the drug; bacterial, viral, fungal skin diseases - pyoderma, chicken pox, herpes, actinomycosis, blastomycosis, sporotrichosis; skin manifestations of syphilis, skin tuberculosis, diaper rash, acne rosacea, extensive psoriatic eruptions (plaques), anogenital itching; trophic ulcers of the leg associated with varicose veins, erosive and ulcerative lesions of the gastrointestinal tract, wounds in the areas of application; skin cancer, nevus, atheroma, melanoma, hemangioma, xanthoma, sarcoma; pregnancy and lactation, child age (up to 2 years). With caution used in girls during puberty.

Drug interactions

Compatible with antimicrobial agents. Reduces the activity of antihypertensives, diuretics, antiarrhythmic drugs, potassium preparations. Diuretic drugs (except potassium-sparing) increase the risk of hypokalemia.

Pregnancy and Lactation

Contraindicated in pregnancy and lactation.

Special instructions

Apply only short courses on small areas of the skin. The drug should not be applied to the face. Avoid contact with eyes. The duration of the appointment in children should not exceed 5 days. Wear free clothing during treatment. Patients with ordinary or pink acne with the treatment may have an exacerbation of the disease. To prevent local infectious complications, it is recommended to prescribe it in combination with antimicrobial agents. Without a prescription.

Overdosage

Symptoms: itching, burning of the skin at the site of application of the ointment, hyperglycemia, glycosuria, Itsenko-Cushing syndrome.
Treatment: symptomatic against the background of gradual withdrawal of the drug.