Fluomizin® [Dequalinium chloride]

Brand Medinova

In stock 1659 Items

Available since: 2019-09-19

Dosage form

pills

Brand & Manufacturer

Package Size

10 mg 6 pcs

$38.06

Quantity

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Clinical Pharmacology

Pharmacotherapeutic group

Antiseptic.

ATX Code: G01AC05

Pharmacological properties

Pharmacodynamics.

Fluomizin® contains the active substance dequalinium chloride, which is a quaternary ammonium compound with a broad spectrum of antimicrobial activity. Dequalinium chloride is active against most Gram-positive bacteria Streptococcus spp., Including (beta-hemolytic streptococci of groups A and B), Staphylococcus aureus, Listeria spp .; anaerobes Peptostreptococcus (group D), fungi of the genus Candida (Candida tropicalis, Candida albicans, Candida glabrata), Gram-negative bacteria Gardnerella vaginalis, Escherichia coli, Serratia spp., Klebsiella spp., Pseudomonas spp., Proteus spp., Pseudomonas spp., Proteus spp., Klebsiella spp., Pseudomonas spp., Proteus spp., Pseudomonas spp., Proteus spp., Klebsiella spp., Pseudomonas spp., Proteus spp., Pseudomonas spp., Serratia spp. ).

Pharmacokinetics. With intravaginal administration, an extremely small amount of dequalinium chloride is absorbed through the mucous membrane of the vagina into the systemic circulation, is metabolized to the derivative of 2,2-dicarboxylic acid and excreted in an unconjugated form through the intestines.

Indications

• bacterial vaginosis

• candidal vaginitis

• trichomonas vaginitis

• reorganization of the vagina before gynecological operations and childbirth.

Composition

The composition of 1 tablet:

Active ingredient: dekaliniya chloride 10 mg

Excipients: lactose monohydrate, microcrystalline cellulose, magnesium stearate.

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Dosage and Administration

The recommended dosing regimen is 1 vaginal tab. / Day. A vaginal tablet is inserted deep into the vagina in the evening before bedtime, lying on its back, with its legs slightly bent. During menstruation, treatment should be stopped and continue the previous course after its completion. It is necessary to conduct a full course of treatment (6 days) in order to avoid relapse.

Adverse reactions

Extremely rarely, local irritation (erosion) reactions, itching, burning or redness at the injection site can be observed. However, these adverse reactions may also be associated with symptoms of a vaginal infection.

Extremely rare fever, allergic reactions.

Contraindications

Hypersensitivity to the drug. Ulcerative lesions of the epithelium of the vagina and cervix.

The use of dequinium chloride before sexual activity is not recommended.

Drug interactions

Fluomizin® is incompatible with soap and other anionic surfactants.

Pregnancy and Lactation

The drug is approved for use throughout the period of pregnancy and lactation.

Special instructions

Fluomizin® contains excipients that sometimes do not completely dissolve in the vagina. Therefore, residues of the vaginal pills can be found in underwear. This does not affect the effectiveness of Fluomizin®.

In rare cases, with excessive vaginal dryness, it is likely that the pill will remain undissolved. To prevent this, before you enter the vaginal tablet, it must be moistened with water (for 1 second under a stream of water).

During the period of treatment it is recommended to change the pads and underwear more often. If the clinical signs of infection persist after completion of treatment, a microbiological examination should be repeated to identify the causative agent and confirm the diagnosis.

During the period of drug treatment is recommended to refrain from sex. To prevent urogenital reinfection, simultaneous treatment of sexual partners is necessary.