Buy Chorionic gonadotropin vials 1500 IU, 5 ml, 5 pcs

Human chorionic gonadotropin (hCG)

Brand Moscow Endocrine Plant

Dosage form

syringe
vials

Brand & Manufacturer

Package Size

5000 U, 5 ml, 5 pcs
1000 IU, 5 ml, 5 pcs
1500 IU, 5 ml, 5 pcs

$64.94

Quantity

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Clinical Pharmacology

Chorionic gonadotropin - gonadotropic hormone. It is produced by human placenta and excreted into the urine, from where it can be extracted and purified. Stimulates the production of progesterone by the corpus luteum and supports the development of the placenta. It has gonadotropic action, mainly luteinizing.

In women, the drug causes ovulation and stimulates the synthesis of estrogen and progesterone. In men, it stimulates spermatogenesis and the production of sex steroids.

Pharmacokinetics

After the / m injection is well absorbed. T1 / 2 is 8 h.

It is believed that before excretion with urine, chorionic gonadotropin is modified in the body, since its T1 / 2, measured by the immunological method, significantly exceeds this indicator, determined by biological activity.

Indications

For women: induction of ovulation after stimulation of follicle growth; maintaining the function of the corpus luteum of the ovary in patients with luteal phase insufficiency.

For boys and men: cryptorchidism (ectopia, testicular retention in the abdominal cavity or in the inguinal canal); delayed puberty; hypogonadotropic hypogonadism (in combination with human menopausal gonadotropin preparations); during the differential diagnostic test for anorchism and cryptorchidism in boys; when conducting a functional Leydig test to assess testicular function in hypogonadotropic hypogonadism before beginning a long-term stimulatory treatment

Composition

1 bottle contains:

Active substance: chorionic gonadotropin 1000 ED.

Human chorionic gonadotropin (hCG) is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
Chorionic gonadotropin	Moscow Endocrine Plant	Russia	vials
Ovitrelle®	Merck Serono	Switzerland	syringe

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Dosage and Administration

Chorionic gonadotropin administered intramuscularly. The dose is individualized depending on the nature, severity of the disease and the age of the patient and ranges from 500 to 3000 units per day.

For men, the drug is administered 2-3 times a week in courses of 4 weeks at intervals of 4-6 weeks. Conduct 3-6 courses for 6-12 months. Prolonged continuous use of the drug is not recommended because of the risk of antibody formation and suppression of the pituitary gonadotropic function.

With anovulatory cycles with a high level of estrogen in women, which indicates the normal maturation of the follicles, the drug is administered from the 10th to the 12th day of the cycle, 3000 IU 2-3 times with an interval of 2-3 days or 1500 IU 6-7 times day.

Adverse reactions

On the part of the endocrine system in women:may develop ovarian hyperstimulation syndrome, accompanied by the development of ovarian cysts with the risk of rupture, ascites, hydrothorax and the risk of thromboembolism.

On the part of the endocrine system in boys and men: temporary reversible enlargement of the mammary glands, prostate gland, water and electrolyte retention, and acne are possible; in boys, behavioral changes similar to those observed during the first phase of puberty, which take place after the end of treatment, are possible.

Contraindications

Tumors of various localization, dependent on sex hormones;
organically induced cryptorchidism (inguinal hernia, consequences of surgical interventions in the inguinal region, abnormal position of the testicles) in boys and men;
hypersensitivity to human chorionic gonadotropin.

Drug interactions

Chorionic gonadotropin is used in combination with menopausal gonadotropin in the treatment of infertility.

Special instructions

Solutions are prepared immediately before use in an isotonic solution of sodium chloride. It is necessary to take into account the probability of false-positive results of immunological analysis for the content of endogenous chronic hepatitis and the possibility of increasing the concentration of 17-hydroxycorticosteroids and 17-ketosteroids in the urine.