Hyaluronic acid
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2019-09-19
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Clinical Pharmacology
Chondroreparative.
Composition
1 ml contains:
Active substances:
zinc hyaluronate and hyaluronic acid copolymer with sodium ascorbyl phosphate - 8 mg / ml
L-cysteine - 1 mg / ml
L-glutathione - 3 mg / ml
Excipients: sodium chloride; phosphate buffer; water for injections
Hyaluronic acid is marketed under different brands and generic names, and comes in different dosage forms:
| Brand name | Manufacturer | Country | Dosage form |
|---|---|---|---|
| HYALREPAIR®-10 | bottle | ||
| Gilan Ultra Comfort | Grotex Ltd | Russia | solution |
| Dermaklinik | VIS Ltd | Russia | capsules |
| HIALRIPIER-02 | Laboratory Tuscany | Russia | bottle |
| HIALRIPIER-02 | Laboratory Tuscany | Russia | syringe |
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Dosage and Administration
In the projection of the zone of damage to the ligament apparatus or the tendon channels. The dosage and depth of the introduction of the medical device GIALRIPAIR-10 (chondroreparant), as well as the selection of the injection needle is determined by the specialist individually.
Depending on the anatomical and physiological characteristics and the state of the soft tissues, it is recommended to administer 0.2–0.5 ml of the solution 1 time in 14 days for 6–8 weeks. A second course is held in 6–12 months. Simultaneously, you can treat several zones.
- Brand name: HYALREPAIR®-10
- Active ingredient: Hyaluronic acid
- Dosage form: Gel material based on 0.8% modified hyaluronic acid, water-containing sterile. In a glass bottle on 5 ml (1 needle is included in the package). Content is sterilized.
- Manufacturer: Laboratory Tuscany
Studies and clinical trials of Hyaluronic acid (Click to expand)
- Cohen syndrome with high urinary excretion of hyaluronic acid
- Hyaluronic acid as drug delivery for sodium butyrate: Improvement of the anti-proliferative activity on a breast-cancer cell line
- Maternal serum hyaluronic acid is ineffective for Down syndrome screening
- Effects of the addition of hyaluronate segments with different chain lengths on the viscoelasticity of hyaluronic acid solutions
- Change in molecular weight of hyaluronic acid during measurement with a cone-plate rotational viscometer
- Properties of collagen and hyaluronic acid composite materials and their modification by chemical crosslinking
- Crosslinking of hyaluronic acid with water-soluble carbodiimide
- Efficacy of hyaluronic acid/nonsteroidal anti-inflammatory drug systems in preventing postsurgical tendon adhesions
- Cartilage tissue engineering with novel nonwoven structured biomaterial based on hyaluronic acid benzyl ester
- Retention of hyaluronic acid in alginate beads: Aspects for in vitro cartilage engineering
- New strategy for chemical modification of hyaluronic acid: Preparation of functionalized derivatives and their use in the formation of novel biocompatible hydrogels
- Synthesis and characterization of polypyrrole–hyaluronic acid composite biomaterials for tissue engineering applications
- Hyaluronic acid stimulates human fibroblast proliferation within a collagen matrix
- Hyaluronic acid enhances proliferation and chondroitin sulfate synthesis in cultured chondrocytes embedded in collagen gels
- Interaction between CD44 and the repeat domain of ankyrin promotes hyaluronic acid-mediated ovarian tumor cell migration
- Hyaluronic acid enhances peripheral nerve regeneration in vivo
- Crosslinking of hyaluronic acid with glutaraldehyde
- Hyaluronic acid and sulfated hyaluronic acid in aqueous solution: effect of the sulfation on the protonation and complex formation with Cu2+ and Zn2+ ions
- Gelation of hyaluronic acid through annealing
- Production of interferon induced by hyaluronic acid from Rous sarcoma
- A human liposarcoma cell line producing hyaluronic acid
- Analysis of hyaluronic acid in the diagnosis of malignant mesothelioma
- Solution structure of hyaluronic acid oligomers by experimental and theoretical NMR, and molecular dynamics simulation
- Anomalous migration of hyaluronic acid oligomers in capillary electrophoresis: Correlation to susceptibility to hyaluronidase
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