Buy Hydrocortisone ointment 1% 10 g
  • Buy Hydrocortisone ointment 1% 10 g


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Clinical Pharmacology

The combined drug, inhibits the development of inflammatory skin reactions, especially of allergic origin, complicated by bacterial infection, as a result of the total action of the components that make up the drug. Oxytetracycline is an antibiotic from the tetracycline group, has a bacteriostatic effect. Active against Gram-positive and Gram-negative bacteria, Rickettsia spp., Treponema spp., Chlamydia spp., Mycoplasma spp. Hydrocortisone - glucocorticosteroid, has anti-inflammatory, anti-allergic, anti-exudative and antipruritic effects. Inhibits phagocytosis; reduces the synthesis of prostaglandins and leukotrienes by inhibiting the activity of phospholipase A2 and reducing the release of arachidonic acid from the phospholipids of cell membranes. Inhibits the release of interleukins and other cytokines that cause the inflammatory process; inhibits the release of histamine and the occurrence of local allergic reactions. Reduces the synthesis of proteins and the deposition of collagen in the skin, prevents the development of connective tissue, weakens proliferative processes.


Newborn dermatitis (cystic and exfoliative), infected diaper rash, folliculitis, furunculosis, carbuncle, impetigo, erysipelas; infected eczema and wounds, erosion; urticaria of the newborn; simple and allergic dermatitis, seborrhea; "Sunny" erythematous rashes; erythema multiforme exudative; insect bites; allergic and suppurative diseases of the external auditory canal; varicose ulcers of the leg, burns, frostbite.


Composition per 1 g:

Active ingredient: hydrocortisone acetate - 10.0 mg; excipients: petrolatum, lanolin, pentaerythritol dioleate (pentol), stearic acid 95, methyl parahydroxybenzoate, propyl parahydroxybenzoate, purified water.

Hydrocortisone is marketed under different brands and generic names, and comes in different dosage forms:

Brand nameManufacturerCountryDosage form
Hydrocortisone Nizhpharm Russia ointment
Pimafucort Astellas Netherlands ointment
Locoid Crelo Astellas Netherlands emulsion
Locoid Astellas Netherlands ointment
Locoid Astellas Netherlands cream
Hydrocortisone Synthesis Russia ointment
Posterisan forte Dr kade Germany rectal suppositories
Posterisan forte Dr kade Germany ointment
Posterized Dr kade Germany rectal suppositories
Hydrocortisone Tatkhimpharmpreparaty Russia ointment
Lokoid Lipokrem Astellas Netherlands cream
Laticort Elfa Pharmaceutical Plant Poland ointment
Cortef Pfizer USA pills
Hydrocortisone pos Ursapharm Artsnaymittel Germany ointment
Solu Cortef Pfizer USA lyophilisate

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Dosage and Administration

Locally, externally.

Ointment in the amount of 0.5-1 g is applied with a thin layer to the affected skin 1-3 times a day or under a sterile gauze bandage.

The duration of treatment is individual.

Adverse reactions

Rarely possible - allergic reactions, skin irritation, itching, rash. With prolonged use and / or application to large surfaces - systemic side effects of glucocorticosteroids. When applied to the skin of the face - possible telangiectasia, atrophy of the subcutaneous tissue in the mouth.


Hypersensitivity, skin tuberculosis, skin tumors, precancerous conditions, mycosis, viral skin diseases (herpes, chicken pox); pregnancy, lactation (when applied to extensive lesions).

Drug interactions

Cases of interaction or incompatibility with other drugs are not described.

Special instructions

During treatment with glucocorticosteroids (GCS), smallpox vaccination should not be given and other types of immunization should be planned (due to the immunosuppressive effect of GCS).


Cases of overdosing Hyoxizone ointment have been reported.

  • Active ingredient: Hydrocortisone

Studies and clinical trials of Hydrocortisone (Click to expand)

  1. Flutamide withdrawal plus hydrocortisone resulted in clinical complete response in a patient with prostate carcinoma
  2. Selective effects of hydrocortisone on intestinal lipoprotein and apolipoprotein synthesis in the human fetus
  3. Retinoic acid inhibits hydrocortisone-stimulated expression of phenol sulfotransferase in bovine bronchial epithelial cells
  4. Separation of hydrocortisone and epi-hydrocortisone by solvent extraction
  5. Bioconversion of hydrocortisone to prednisolone by immobilized bacterial cells in a two-liquid-phase system
  6. Antitumor activity of suramin in hormone-refractory prostate cancer controlling for hydrocortisone treatment and flutamide withdrawal as potentially confounding variables
  7. Fixed higher dose schedule of suramin plus hydrocortisone in patients with hormone refractory prostate carcinoma : A multicenter Phase II study
  8. Effects of hydrocortisone on the formation of gap junctions and the abnormal growth of cilia within the rat anterior pituitary gland: Possible role of gap junctions on the regulation of cell development
  9. Alterations in shock-induced fighting and locomotor activity following intracerebroventricular injection of hydrocortisone in the rat
  10. Disposition of intra-articularly injected cortisone and hydrocortisone
  11. Hypophysis-adrenal system in the fetal rat. Effects of hydrocortisone, cortisone, DCA, adrenalectomy and maternal hypophysectomy upon the hypophysis
  12. The effect of hydrocortisone on extracellular connective tissue fibrils in the early chick embryo
  13. Light and electron microscopic observations on hydrocortisone-induced cleft palate in hamsters
  14. Qualitative and quantitative morphologic study of peyer's patches of the mouse after neonatal thymectomy and hydrocortisone injection
  15. Morphological development of the epithelium of the embryonic chick intestine in culture: Influence of thyroxine and hydrocortisone
  16. Mechanisms of increased brain glucose and glycogen after hydrocortisone: Possible clinical significance
  17. Effect of blending methyl β-cyclodextrin on the release of hydrophobic hydrocortisone into water from polyurethane
  18. Some effects of exogenous hydrocortisone on pregnancy in the rat
  19. Similarity of congenital malformations produced by hydrocortisone to those produced by adrenalectomy in guinea pigs
  20. The differential effect of hydrocortisone on the short-lived small lymphocyte
  21. Role of chondrocytes and hydrocortisone in resorption of proximal fragment of Meckel's cartilage: An in vitro and in vivo study
  22. Resistance to therapy in mature palmerston north mice treated with cyclophosphamide or hydrocortisone sodium succinate
  23. Effect of cyclophosphamide, hydrocortisone, and levamisole on collagen-induced arthritis in rats
  24. The effects of in vivo hydrocortisone on lymphocyte-mediated cytotoxicity

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