Lespedeza tincture
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Clinical Pharmacology
Lespeflan has a hypoazotemic effect, helps reduce the content of nitrogen metabolism products in the blood, increases the clearance of nitrogenous compounds (urea, creatinine, uric acid), increases glomerular filtration, and has a moderate diuretic effect. Lespeflan also has anti-inflammatory effects.
Indications
Lespeflane is used in adults as a hypoazotemic, diuretic and anti-inflammatory agent in the complex treatment of chronic renal failure of various origins in the latent compensated and intermittent stages.
Composition
active substances: Lespedesa two-color shoots; ethanol (ethyl alcohol) 95%; purified water; anise oil
Lespedeza tincture is marketed under different brands and generic names, and comes in different dosage forms:
Brand name | Manufacturer | Country | Dosage form |
---|---|---|---|
Lespeflan | Dalkhimpharm | Russia | vials |
Lespefril | Vifitekh TOO | Russia | vials |
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Dosage and Administration
Lespeflan apply inside 5-15 ml (1 tea-tablespoon) 3-4 times a day. It is allowed to dilute the main solution before drinking water. The course of treatment is 3-4 weeks. If necessary, the course can be repeated after a two-week break. Allowed to increase the daily dose of Lespeflan up to 80-100 ml per day with the extension of treatment to 6 weeks.
Adverse reactions
Allergic reactions are possible, in rare cases - hyponatremia.
Contraindications
Individual intolerance to the components Lespeflan. Pregnancy.
Drug interactions
Due to the presence of alcohol, it is impossible to prescribe the drug to patients receiving treatment with drugs that depress the central nervous system, insulin, hypoglycemic agents (metformin, sulfonylurea derivatives); drugs that cause intolerance to alcohol (disulfiramopodobnoe action).
Special instructions
With the development of hyponatremia, it should be compensated by the introduction of sodium.
The maximum daily dose of the drug contains 18.9 g of absolute alcohol, as a result of which it is possible to decrease the speed of psychomotor reactions, which should be taken into account when driving and working that requires concentration and speed of psychomotor reactions.