Linex®
Sandoz
635 Items
2019-09-19
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Clinical Pharmacology
Linex® normalizes intestinal microflora. One capsule of the drug Linex® contains at least 1.2 x 107 live lyophilized lactic acid bacteria: Lactobacillus acidophilus, Bifidobacterium infantis, Enterococcus faecium. Live lactic acid bacteria are a normal component of the natural intestinal microflora and are already contained in the digestive tract of a newborn baby. These bacteria are of great biochemical importance to the human body:
- fermentation of lactose shifts the pH to the acidic side. Acidic environment inhibits the growth of pathogenic and conditionally pathogenic bacteria and ensures optimal action of digestive enzymes;
- participate in the synthesis of vitamins B, K, ascorbic acid, thereby increasing the body's resistance to adverse environmental factors;
- participate in the metabolism of bile pigments and bile acids;
- synthesize substances with antibacterial activity;
- boosts the body's immune reactivity.
Indications
Treatment and prevention of dysbacteriosis. Dysbacteriosis is manifested by the following symptoms: diarrhea (diarrhea), dyspepsia (indigestion), constipation, flatulence (bloating), nausea, belching, vomiting, abdominal pain, allergic skin reactions are possible.
Composition
1 capsule contains: active ingredient: Lebenin®? 280.00 mg (1 g of the active ingredient Lebenin®, powder contains: Lactobacillus acidophilus (species L.gasseri)? 300 mg, Bifidobacterium infantis? 300 mg, Enterococcus faecium? 300 mg, lactose? 50 mg, potato starch? 50 mg ); excipients: magnesium stearate? 8.40 mg; capsule shell? methyl hydroxybenzoate? 0.19 mg, propyl hydroxybenzoate? 0.08 mg titanium dioxide (E171)? 0.98 mg gelatin? up to 63.0 mg.
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Dosage and Administration
For oral use.
Linex® should be taken after meals with a small amount of liquid. Children under 3 years old and patients who can not swallow a whole capsule, it is necessary to open it, pour the contents into a spoon and mix with a small amount of liquid.
Newborns and children up to 2 years: 1 capsule 3 times a day;
Children from 2 to 12 years: 1-2 capsules 3 times a day
Adults and teenagers older than 12 years: 2 capsules 3 times a day. The duration of treatment depends on the cause of the development of dysbiosis and the individual characteristics of the organism.
Adverse reactions
The drug is well tolerated.
There are no reports of adverse effects, but the possibility of hypersensitivity reactions cannot be ruled out.
Contraindications
Hypersensitivity to any of the components of the drug or dairy products.
Drug interactions
Undesirable interactions with other drugs are not marked.
The composition of the drug allows you to take LINEX simultaneously with other drugs, including antibiotics and chemotherapeutic drugs.
Pregnancy and Lactation
The use of Linex during pregnancy and Lactation is considered safe.
Special instructions
Do not drink Linex® with hot drinks and take it with alcohol at the same time. You must consult with your doctor before taking the drug if you have:
- body temperature above 38 ° C,
- traces of blood or mucus in the stool,
- diarrhea lasts more than two days and is accompanied by acute abdominal pain, dehydration and weight loss,
- chronic diseases - diabetes, AIDS.
When treating diarrhea, it is necessary to replace lost fluid and electrolytes.
INFLUENCE ON ABILITY TO CONCENTRATION OF ATTENTION
Linex® does not affect psychophysical activity.
Overdosage
Currently, the cases of drug overdose Linex were reported.
- Brand name: Linex
- Active ingredient: Lactobacillus acidophilus, Bifidobacterium infantis, Enterococci
- Dosage form: Capsules
- Manufacturer: Sandoz
- Country of Origin: Switzerland
Studies and clinical trials of Linex (Click to expand)
- Bayesian estimation under Poisson testing using the LINEX loss function
- Empirical Bayes testing procedures in some nonexponential families using asymmetric Linex loss function
- Risk of a homoscedasticity pre-test estimator of the regression scale under LINEX loss
- Convergence rate of empirical Bayes estimation for two-dimensional truncation parameters under linex loss
- Shrinkage estimation in exponential type-II censored data under LINEX loss
- Empirical Bayes estimators of reliability performances using LINEX loss under progressively Type-II censored samples
- Minimax and Γ-minimax estimation for the Poisson distribution under LINEX loss when the parameter space is restricted
- On a Bayesian aspect for soft wavelet shrinkage estimation under an asymmetric Linex loss
- Admissible estimation for finite population under the Linex loss function
- Empirical Bayes analysis of record statistics based on linex and quadratic loss functions
- On the admissibility of an estimator of a normal mean vector under a linex loss function
- New biased estimators under the LINEX loss function
- On the sampling performance of an inequality pre-test estimator of the regression error variance under LINEX loss
- Risk performance of a pre-test estimator for normal variance with the Stein-variance estimator under the LINEX loss function
- Estimation of the location parameter under LINEX loss function: multivariate case
- Bayes sequential estimation for a particular exponential family of distributions under LINEX loss
- Sequential point estimation of normal mean under LINEX loss function
- On estimating the mean of the selected normal population under the LINEX loss function
- Optimal sequential estimation procedures of a function of a probability of success under LINEX loss
- A Study of the Internal Boundary Layer due to a Roughness Change in Neutral Conditions Observed During the LINEX Field Campaigns
- LINEX Loss Functions with Applications to Determining the Optimum Process Parameters
- Optimal process parameters under LINEX loss function with general input quality characteristic
- Minimax estimation of a probability of success under LINEX loss
- Minimax Invariant Estimator of Continuous Distribution Function Under Linex Loss
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