Lisinopril

Brand Ipka

In stock 1298 Items

Available since: 2019-09-19

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Clinical Pharmacology

Lisoril has an antihypertensive effect.

Indications

Arterial hypertension (including those complicated by conditions such as diabetes, gout, asthma, depression), congestive heart failure.

Composition

1 tablet contains lisinopril 10 mg.

Lisinopril is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
Lizoril	Ipka	India	pills
Lisinopril-Teva	Teva	Israel	pills
Lisinopril	Vertex	Russia	pills
Lisinopril	Hemofarm	Serbia	pills
Lisinopril-Teva	Teva	Hungary	pills
Diroton	Gedeon Richter	Hungary	pills
Lizinoton	Actavis Ltd	Iceland	pills
Irumed	Belupo	Croatia	pills

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Dosage and Administration

Lisoril is adminstered orally. In case of arterial hypertension: the initial dose is 5 mg once a day, if necessary up to 40 mg / day. In case of congestive heart failure: the initial dose is 2.5 mg, if necessary up to 20 mg / day. Against the background of violations of water and electrolyte balance, diuretic therapy of renal failure, with renovascular hypertension, the initial dose is 1.25 mg / day.

Adverse reactions

From the nervous system and sensory organs: headache, dizziness.

On the part of the digestive tract: nausea, vomiting, increased activity of hepatic transaminases.

Since the cardiovascular system and blood (hematopoiesis, hemostasis): hypotension, tachycardia, neutro / thrombocytopenia, decrease in hemoglobin level.

On the part of the respiratory system: dry cough, bronchitis.

Allergic reactions: angioedema, skin rash.

Other: muscle spasms, hyperkalemia, impaired renal function.

Contraindications

Hypersensitivity, angioedema, renal artery stenosis, aortic stenosis, renal dysfunction, pregnancy, breast-feeding.

Drug interactions

With simultaneous use with NSAIDs, estrogens and sympathomimetics, a decrease in the effectiveness of Lisoril is possible.
Combined use with beta-blockers, calcium channel blockers, diuretics and other antihypertensives increases the severity of Lizoril's hypotensive action.
With simultaneous use of Lisoril with potassium-sparing diuretics, hyperkalemia may develop.
When used in combination with lithium preparations, Lisoril may slow down the elimination of lithium from the body.

Pregnancy and Lactation

Lisoril is contraindicated for use in pregnancy.
If necessary, use Lizorila during lactation should decide on the termination of breastfeeding.

Special instructions

With caution, the drug is prescribed to patients with impaired renal function, as well as patients receiving diuretics.
In cases of allergic reactions, treatment with Lisoril should be discontinued.
Control of laboratory parameters
Before starting therapy with Lisoril, it is necessary to monitor the laboratory indicators of renal function, water-electrolyte metabolism and, if necessary, compensate for the loss of fluid and salt. In the course of treatment, blood leukocyte count should be periodically monitored, especially in patients with autoimmune and renal diseases, as well as the content of potassium in the blood plasma.