Microlax

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Available since: 2019-09-19

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Clinical Pharmacology

Combined laxative drug. Sodium citrate is a peptizer that displaces the bound water contained in fecal masses. Sodium lauryl sulfoacetate dilutes intestinal contents. Sorbitol enhances the laxative effect by stimulating the entry of water into the intestines. Increasing the amount of water due to peptization and liquefaction helps soften the feces and facilitates the process of bowel emptying.

The laxative effect occurs within 5-15 minutes after taking the drug.

Indications

- constipation (including with encopresis);

- preparation for endoscopic (rectoscopy) and X-ray examination of the gastrointestinal tract.

Composition

The solution for rectal administration is colorless, opalescent, viscous.

	1 ml
sodium citrate	90 mg
sodium lauryl sulfoacetate 70%	12.9 mg,
which corresponds to the sodium content of lauryl sulfoacetate	9 mg
sorbitol solution 70%	893 mg
which corresponds to the content of sorbitol	625 mg

Excipients: sorbic acid - 1 mg, glycerol - 125 mg, purified water - up to 1 ml.

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Dosage and Administration

1. Break off the seal at the tip of the tube.

2. Gently press on the tube so that a drop of the drug smears the tip of the enema (to facilitate the introduction process).

3. When using microclysters in 5 ml in children under 3 years of age, the enema should be inserted into the rectum half the length, children over the age of 3 and adults should enter the entire enema tip.

4. Squeezing the tube, squeeze out all its contents.

5. Remove the tip while continuing to squeeze the tube slightly.

Adverse reactions

Adverse reactions that occur during the use of the drug, which were detected during the period of post-registration use, are classified as follows: very often (≥10%), often (≥1%, but

On the part of the digestive system: very rarely - pain in the abdomen (including abdominal discomfort, pain in the upper abdomen), discomfort in the anorectal region, and liquid stool.

Allergic reactions: very rarely - hypersensitivity reactions (for example, urticaria).

Contraindications

increased individual sensitivity to the components of the drug.

Drug interactions

There is a risk of colon necrosis with simultaneous oral / rectal use of sodium polystyrene sulfonate and sorbitol, which is part of the drug.

Pregnancy and Lactation

Adequate and strictly controlled studies with the participation of pregnant women were not conducted. Since the drug is probably absorbed into the systemic circulation to a small extent; when used in accordance with recommendations during pregnancy or lactation, no adverse effects are expected for the fetus or infant.

Special instructions

Long-term use of the drug should be avoided; if symptoms persist, the patient should consult a doctor.

The patient should be informed that if the drug has become unusable or the expiration date has expired, it should not be thrown into the wastewater or outside. It is necessary to put the drug in the bag and put it in the trash. These measures will help protect the environment.

Influence on ability to drive motor transport and control mechanisms

Microlax does not affect the ability to drive and control machinery.