Milk thistle
Pharmacentre VILAR ZAO
531 Items
2019-09-19
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Clinical Pharmacology
Silymar - hepatoprotective drug of plant origin.
It has hepatoprotective and anti-toxic effects. The therapeutic effect is due to the effect on the metabolism of hepatocytes. It activates the synthesis of proteins and enzymes in hepatocytes, has a stabilizing effect on the membrane of hepatocytes, inhibits the penetration of toxins into the liver cells, inhibits dystrophic and potentiates the regenerative processes in the liver.
Indications
- Toxic liver damage;
- chronic hepatitis;
- cirrhosis of the liver (as part of complex therapy);
- condition after suffering hepatitis;
- in order to prevent chronic intoxication (including professional), long-term medication and alcohol.
Composition
1 tablet contains:
Active substances: milk thistle fruit extract - 100 mg.
Excipients: lactose, potato starch, magnesium stearate.
Milk thistle is marketed under different brands and generic names, and comes in different dosage forms:
| Brand name | Manufacturer | Country | Dosage form |
|---|---|---|---|
| Silymar | Pharmacentre VILAR ZAO | Russia | pills |
| Carsil® | Sopharma | Bulgaria | dragee |
| Legalon 140 | Madus | Germany | capsules |
| Legalon 70 | Madus | Germany | capsules |
| Carsil® | Sopharma | Bulgaria | capsules |
No customer reviews for the moment.
Dosage and Administration
Assign inside adults 1-2 tab. 3 times / day The course of treatment is 25-30 days. If necessary, repeat the course in 1-3 months.
The drug is taken 30 minutes before a meal.
Adverse reactions
Perhaps - allergic reactions.
In some cases - laxative action.
Contraindications
Hypersensitivity to the drug.
Drug interactions
Data on drug interactions drug Silymar not provided.
Pregnancy and Lactation
It is not recommended to prescribe the drug during pregnancy and lactation (breastfeeding).
Special instructions
Use in Pediatrics
It is not recommended to prescribe the drug to children under the age of 12 years.
Overdosage
Data on overdose of the drug Silymar not provided.
- Brand name: Silymar
- Active ingredient: Milk thistle fruit extract
- Dosage form: Pills.
- Manufacturer: Pharmacentre VILAR ZAO
- Country of Origin: Russia
Studies and clinical trials of Milk thistle (Click to expand)
- Medical Toxicology of Natural Substances || Milk Thistle [Silybum marianum (L.) Gaertner]
- Complete Isolation and Characterization of Silybins and Isosilybins from Milk Thistle (Silybum marianum).
- A randomized, controlled, double-blind, pilot study of milk thistle for the treatment of hepatotoxicity in childhood acute lymphoblastic leukemia (ALL)
- Milk thistle and chronic liver disease
- Clinical assessment of CYP2D6-mediated herb–drug interactions in humans: Effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea
- Pretreatment of milk thistle seed to increase the silymarin yield: An alternative to petroleum ether defatting
- Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography–electrospray tandem mass spectrometry
- ASsessment of botanical supplementation on human cytochrome P450 phenotype: citrus aurantium, echinacea, milk thistle, saw palmetto.
- In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: , , milk thistle, and saw palmetto
- Assessment of milk thistle and black cohosh supplementation on digoxin pharmacokinetics
- Application of response surface methodology to optimize microwave-assisted extraction of silymarin from milk thistle seeds
- Stability of the constituents of Calendula, Milk-thistle and Passionflower tinctures by LC-DAD and LC-MS
- Batch solvent extraction of flavanolignans from milk thistle (Silybum marianum L. Gaertner)
- Milk thistle in liver diseases: past, present, future
- Characterization of calendula flower, milk-thistle fruit, and passion flower tinctures by HPLC-DAD and HPLC-MS
- Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis
- Consumption of silibinin, a flavonolignan from milk thistle, and mammary cancer development in the C3(1) SV40 T,t antigen transgenic multiple mammary adenocarcinoma (TAg) mouse
- Interaction of milk-thistle-fruit flavanonols with Langmuir monolayers of lecithin and bilayers of liposomes
- Are polyamines directly involved in silymarin production in the milk thistle [Silybum marianum(L.) Gaernt]?
- Evaluation of the yeast-extract signaling pathway leading to silymarin biosynthesis in milk thistle hairy root culture
- Characterization of cold-pressed onion, parsley, cardamom, mullein, roasted pumpkin, and milk thistle seed oils
- Characterization of Cold-Pressed Onion, Parsley, Cardamom, Mullein, Roasted Pumpkin, and Milk Thistle Seed Oils
- Milk Thistle Seed Oil Constituents from Different Varieties Grown in Iran
- Biology of milk thistle (Silybum marianum) and the management options for growers in north-western Pakistan
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