Natecal D3
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Clinical Pharmacology
Natecal D3 is a combined drug that regulates the exchange of calcium and phosphorus in the body. Reduces resorption (resorption) and increases bone density, replenishing the lack of calcium and vitamin D3 in the body.
Vitamin D3 increases calcium absorption in the gastrointestinal tract and its binding in the bone tissue. Calcium and Vitamin D3 prevents an increase in parathyroid hormone production (which is a stimulator of increased bone resorption (leaching of calcium from the bones)
Indications
Osteoporosis (menopausal, senile, steroid, idiopathic, etc.) and its complications, incl. bone fractures (prophylaxis and complex therapy); replenishment of calcium and vitamin D deficiency3 (including in the elderly).
Composition
Active ingredients: calcium carbonate - 1500 mg (equivalent to Ca2 + - 600 mg), cholecalciferol - 400 IU (equivalent to dry vitamin D3 - 4 mg);
Excipients: sorbitol, maltodextrin, croscarmelose sodium, aspartame, sodium saccharinate, lactose monohydrate, anise flavor, mint flavor, molasses flavor, magnesium stearate; alpha-tocopherol acetate, soybean oil, hydrogenated oil, gelatin, sucrose, corn starch;
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Dosage and Administration
Inside, sucking,as a prophylactic agent: adults - 1-2 pills per day;for course prevention of osteoporosis: 1 tablet 2 times a day, in the morning and in the evening (preferably with meals),for osteoporosis therapy: The dosage and duration of the course are determined by the doctor.
Adverse reactions
Diarrheal phenomena (constipation, diarrhea, flatulence, nausea, abdominal pain); increase of calcium in blood and urine (with prolonged use).
Contraindications
- Hypersensitivity, hypercalcemia, hypercalciuria, urolithiasis, sarcoidosis and metastasis of tumors in the bone, pronounced renal impairment;
- osteoporosis due to prolonged immobilization;
- vitamin D overdose3.
Drug interactions
The effect is weakened by phenytoin and barbiturates, strengthen - cardiac glycosides. Calcium and Vitamin D3 increase the absorption of tetracyclines (required 3-hour interval between doses), reduce - bisphosphonates and fluorides (requires a 2-hour interval between doses). Corticosteroids lower calcium absorption, furosemide and other loop diuretics increase calcium excretion by the kidneys. Cholestyramine and mineral or vegetable oil-based laxatives reduce the absorption of vitamin D3. The acid reaction of food increases the absorption of calcium, weakly alkaline - reduces.
Pregnancy and Lactation
Perhaps, but not more than 1500 mg of calcium and 600 IU of vitamin D3 per day.
Special instructions
Can not be used simultaneously with vitamin-mineral complexes containing calcium and vitamin D3. Consider possible additional intake of vitamin D3 from other sources.