Buy Norbactin pills 400 mg 20 pcs packaging

Norfloxacin

Brand Ranbaxy Laboratories Ltd

In stock 1482 Items

Available since: 2019-09-19

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Clinical Pharmacology

Norbactin is an antibacterial agent from the group of fluoroquinolones. Has a bactericidal effect. It affects the bacterial enzyme DNA gyrase, which provides supercoiling and, thus, the stability of bacterial DNA. Destabilization of the DNA chain leads to the death of bacteria. It has a wide range of antibacterial action.

Indications

Bacterial infections of the urinary tract (pyelonephritis, cystitis, urethritis), genitals (prostatitis, cervicitis, endometritis), gastrointestinal tract (salmonellosis, shigellosis), uncomplicated gonorrhea. Prevention of infections in patients with granulocytopenia, travelers' diarrhea.

Composition

1 tablet contains 400 mg norfloxacin.

Norfloxacin is marketed under different brands and generic names, and comes in different dosage forms:

Brand name	Manufacturer	Country	Dosage form
Norbactin	Ranbaxy Laboratories Ltd	India	pills
Norfloxacin	Obolensky OP	Russia	pills
Normax	Ipka	India	eye drops

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Dosage and Administration

Acute urinary tract infections - 400 mg twice a day for 7-10 days.

Acute uncomplicated cystitis - 400 mg twice a day for 3 days.

Recurrent or chronic infections of the urinary tract with exacerbations - 400 mg twice a day for 4 weeks, then, if necessary, 400 mg per day for up to 12 weeks.

There is evidence of a significant reduction in the frequency of recurrence of urinary tract infections in women with frequent recurrent infections with prophylactic administration of 200 mg of Norbactin once after sexual intercourse.

Chemoprophylaxis for urological interventions, surgeries and for postoperative infections - 400 mg twice a day before and after surgery, as needed.

Acute uncomplicated gonococcal infections - 800 mg once.

Bacterial intestinal infections - 400 mg twice a day for 5 days.

Prevention of travelers' diarrhea - 400 mg once a day (no more than 21 days). The widespread use of antibacterial agents for the prevention of diarrhea is not recommended, they can be used in high-risk areas, in the presence of aggravating factors (hypochlorhydria, the use of antacids and secretion inhibitors, dysgammaglobulinemia) and a high risk of complications due to dehydration in somatic diseases, diuretics, cardiac glycosides.

For better efficacy and tolerability, Norbactin should be taken one hour before or two hours after a meal. It can not be taken with antacids. Patients are advised to drink enough liquid to prevent crystalluria.

Patients with renal insufficiency (creatinine clearance from 10 to 30 ml / min / 1.73 m2) - 400 mg once a day.

Contraindications

Contraindicated in patients with anamnestic indications of hypersensitivity to norfloxacin or any other chemical analogue. It should not be used in patients with severe renal insufficiency (creatinine clearance less than 10 ml / min / 1.73 m2) and pregnant women.

Special instructions

Norbactin should be used with caution in patients with epilepsy, convulsive syndrome of a different etiology, with severe impaired renal function and liver. During treatment, patients should receive a sufficient amount of fluid (under the control of diuresis).

Norbactin should be taken no less than 2 hours before or 2 hours after taking antacids or preparations containing iron, zinc, magnesium, calcium or sucralfate.