Optive®
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Clinical Pharmacology
Belongs to a group of ophthalmic agents in combinations, is an artificial analogue of tears.
Carmellose sodium and glycerol have properties of a protector of the corneal epithelium, improve the moistening of the cornea with reduced secretion of tear fluid and increase the stability of the tear film.
Indications
Symptomatic treatment of dry eye syndrome.
Composition
1 ml contains:
Active substances:
- Carmellose sodium (type 7H3SXF 10-15) 1.75 mg,
- carmellose sodium (type 7M8SFPH) 3.25 mg,
- glycerol 9mg.
Excipients:
Erythritol 2.50 mg, levocarnitine 2.50 mg, boric acid 7.00 mg, sodium borate decahydrate 2.00 mg, sodium citrate dihydrate 1.00 mg, potassium chloride 1.40 mg, calcium chloride dihydrate 0.06 mg, magnesium chloride hexahydrate 0.06 mg, hydroxy-chloro complex stabilized [sodium chlorite, sodium chlorate, chlorine dioxide] 0.10 mg, purified water to 1.00 ml.
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Dosage and Administration
The drug is instilled 1-2 drops in the conjunctival sac as needed.
Adverse reactions
Violations by the organ of vision:often - conjunctival hyperemia, eyelid hyperemia, blurring of vision, feeling of dryness of the eye, discomfort during instillation, itching and eye irritation, formation of crusts on the edge of the eyelid.
In the post-marketing period, the following adverse reactions of the drug Optive were received (frequency unknown): pain in the eye area, appearance of discharge from the eye, foreign body sensation in the eye, eyelid edema, increased tearing, photophobia.
Contraindications
Hypersensitivity to the components of the drug, children under 18 years of age (experience with no).
Carefully: during pregnancy and during breastfeeding (due to limited data).
Drug interactions
Data on drug interactions drug Optiv no.
When prescribing with other local ophthalmological agents, the interval between instillation of the drug Optive and other eye drops should be at least 5 minutes in order to exclude the possibility of "washing out" of the drug.
Pregnancy and Lactation
Strictly controlled studies in pregnant women and nursing mothers was not conducted. In animal studies there was no adverse effect of the active ingredients of the drug.
The optiv is not absorbed from the mucosal surface, thus, there are no objective prerequisites for the possible excretion of its components in breast milk.
Use of the drug during pregnancy and during lactation is possible with caution.
Special instructions
The drug is intended for topical use only. Do not use in violation of the integrity of the film covering the neck of the bottle, clouding of the solution or changing its color.
Do not touch the pipette tip to any surface, including the conjunctiva, to avoid contamination of the vial contents. It is necessary to close the bottle immediately after applying the drug.
The shelf life of the drug after the first opening of the bottle is 28 days. Consult your doctor if you have pain in the eye area, blurred vision, prolonged hyperemia or irritation of the mucous membranes of the eyes. Also, seek advice if there is no improvement in the use of the drug and / or if you have other adverse effects that are increasing or not resolved within 72 hours.
Impact on driving and performance of potentially hazardous activities
If after installation a blurred vision is noted, it is necessary to refrain from driving vehicles and practicing potentially hazardous activities that require increased concentration of attention and quickness of psychomotor reactions until it is restored.
- Brand name: Optive
Studies and clinical trials of Optive (Click to expand)
- Evaluation of the effects on conjunctival tissues of Optive eyedrops over one month usage
- A Comparison of Efficacy Between Systane® Ultra and OPTIVE™ Lubricant Eye Drops When Tested With Dry Eye Patients
- The South African government and the application of co-optive power
- Effect of Systane and Optive on Aqueous Tear Evaporation in Patients With Dry Eye Disease
- The Effect of Optive and Optive Advanced Artificial Tears on the Healthy Tear Film
- A prospective, multicenter, noninterventional study of Optive Plus® in the treatment of patients with dry eye: the prolipid study
- Treatment of patients with keratoconjunctivitis sicca with Optive™: results of a multicenter, open-label observational study in Germany
- The Jewel in the Crown: Co-optive Capacity and Participation During Austerity in Cardiff and San Sebastián-Donostia