Buy Medifox bottle 5%, 24 ml
  • Buy Medifox bottle 5%, 24 ml

Permethrin

Fox and Co.
1724 Items
2019-09-19
Dosage form
Brand & Manufacturer
Package Size
$27.00
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Clinical Pharmacology

Medifox has anti-pediculosal, insecticidal action.

Indications

  • scabies,
  • head lice,
  • pubic lice.

Composition

100 g of concentrate contain:

Active substance: permethrin (in terms of 100% substance) - 5.0 g.

Excipients: Castor medical oil - 7.5 g, butyl acetate - 0.25 g, ethanol 96% - 87.25 g.

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Permethrin

Dosage and Administration

Scabies

A bottle containing 24 ml of the drug (for ease of use, the labels are applied to the bottle) is designed for a three-day course of treatment.

Applied externally in the form of freshly prepared 0.4% aqueous emulsion, for which 1/3 of the contents of the vial (8 ml) is added to 100 ml of warm boiled water. The finished emulsion 1 time per day (overnight) is carefully rubbed into the skin of the upper extremities, torso, and then the lower extremities. The skin of the face and neck, as well as the scalp, shall not be treated.

At the end of the course of treatment on the fourth day, the patient must take a shower and carry out a change of underwear and bed linen.

Head and pubic lice

In the treatment of head and pubic lice used externally in the form of freshly prepared 0.2% aqueous emulsion. To obtain an emulsion, 1/3 of the contents of the vial (8 ml) are added to 200 ml of warm boiled water.

The resulting aqueous emulsion is abundantly applied to wet hair of the head or hairy parts of the body (with pubic pediculosis), gently rubbing into the skin with a cotton swab.

20 minutes after treatment, the agent is rinsed with warm running water and soap (shampoo).

Adverse reactions

In some cases: There may be a burning sensation in places of application of the drug, which passes on its own after a few minutes. Allergic reactions.

Contraindications

  • hypersensitivity
  • acute inflammatory diseases of the scalp.

Pregnancy and Lactation

Contraindicated during lactation, with pregnancy - with caution.

Special instructions

Avoid getting the drug on the mucous membrane of the eyes, nasal passages and oral cavity, as well as on the mucous membrane of the external genital organs. In case of contact with the mucous membranes, they should be washed with running water.

When treating pediculosis, in order to prevent the drug from getting into the eyes of children from 1 year old, wear a protective visor on the head or a kerchief over the face, and wash hands after treatment.

  • Active ingredient: Permethrin

Studies and clinical trials of Permethrin (Click to expand)
  1. P450 monooxygenases are an important mechanism of permethrin resistance in Culex quinquefasciatus Say larvae
  2. Occurrence and mobility of the insecticide permethrin in rivers in the Southern Humber catchment, UK
  3. A new aqueous suspension concentrate formulation of cis-permethrin and its insecticidal activity
  4. Enzymatische Synthesen chiraler Bausteine aus Racematen: Herstellung von (1R,3R)-Chrysanthemum-, -Permethrin- und -Caronsäure aus racemischen Diastereomerengemischen
  5. Sublethal effects of permethrin on the chemical communication system of the pink bollworm moth, Pectinophora gossypiella
  6. Permethrin- and malathion-induced macromolecular abnormalities in adult Tribolium castaneum (herbst)
  7. Some macromolecular abnormalities developed by the interaction of malathion and permethrin and subsequent refeeding in Tribolium castaneum larvae
  8. A solid phase extraction reversed-phase HPLC method for the simultaneous determination of methoprene, permethrin and selected metabolites in rat plasma and urine
  9. ChemInform Abstract: Synthesis and Biological Activity of Permethrin Analogues Containing Various Substituents in Position 2 of the Cyclopropane Ring.
  10. HPLC-method for determination of permethrin enantiomers using chiral β-cyclodextrin-based stationary phase
  11. Effect of permethrin on the induction of sister chromatid exchanges and micronuclei in cultured human lymphocytes
  12. Acute toxicity and behavioral effects of chlorpyrifos, permethrin, phenol, strychnine, and 2,4-dinitrophenol to 30-day-old Japanese medaka (Oryzias latipes)
  13. Toxicity of permethrin to Chironomus riparius in artificial and natural sediments
  14. Enantioselective induction of oxidative stress by permethrin in rat adrenal pheochromocytoma (PC12) cells
  15. Permethrin induces lymphocyte DNA lesions at both Endo III and Fpg sites and changes in monocyte respiratory burst in rats
  16. Cytotoxic effects of permethrin on mouse liver and spleen cells
  17. Degenerative process and cell death in salivary glands of Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) semi-engorged female exposed to the acaricide permethrin
  18. Capillary gas chromatographic separation of some diastereomeric amides from carbonyldiimidazole-mediated microgram-scale derivatizations of the acid moiety of permethrin insecticide
  19. Determination of permethrin and cyfluthrin in water and sediment by gas chromatography-mass spectrometry operated in the negative chemical ionization mode
  20. Determination of cypermethrin, fenvalerate and cis- and trans-permethrin in soil and groundwater by high-performance liquid chromatography using partial least-squares regression
  21. Permethrin-treated bed nets (mosquito nets) prevent malaria in Gambian children
  22. Collateral effects of bednets impregnated with permethrin against bedbugs (Cimicidae) in Papua New Guinea

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