Buy Persen pills 40 pcs
  • Buy Persen pills 40 pcs


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Clinical Pharmacology

Pharmacological group: Sedative of plant origin

ATX code: N05CM

Pharmacological properties:

The drug has a sedative and antispasmodic effect. Extract of rhizomes with valerian roots has a calming effect. Lemon balm leaf extract - soothing and antispasmodic. Peppermint Leaf Extract - antispasmodic, mild sedative effect.


Increased nervous irritability, insomnia, irritability.


1 coated tablet contains: composition of the core: active substances: valerian extract dry - 50,000 mg; dry lemon balm extract - 25,000 mg; peppermint dry extract - 25,000 mg; excipients: talc, magnesium stearate, crospovidone, corn starch, colloidal silicon dioxide, microcrystalline cellulose, lactose; shell composition: hydroxypropylcellulose (Hypromellose, Pharmacoat), talc, sodium carboxymethylcellulose, povidone, sucrose, colloidal silicon dioxide, calcium carbonate, titanium dioxide, brown dye 75, glycerin, E Hoechst wax (Capol 600).

Persen® is marketed under different brands and generic names, and comes in different dosage forms:

Brand nameManufacturerCountryDosage form
Persen Sandoz Switzerland pills
Persen Sandoz Switzerland capsules

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Dosage and Administration

Should be adminsitered orally, flushed with water, regardless of the meal.

Adults and children over 12 years old with increased nervous excitability, irritability are prescribed by 2-3 tab. The drug is taken 2-3 times / day. When insomnia - 2-3 tab. 30 min-1 h before bedtime.

The maximum daily dose is 12 tab.

When discontinuation of treatment, withdrawal does not occur.

Do not use the drug continuously for more than 1.5-2 months.

Adverse reactions

Possible: allergic reactions (hyperemia, skin rash, peripheral edema, allergic dermatitis), bronchospasm, with prolonged; with prolonged use - constipation.


- Lactase deficiency, lactose intolerance, glucose-galactose malabsorption;

- deficiency of sucrase / isomaltase, fructose intolerance;

- arterial hypotension;

- cholangitis, cholelithiasis and other diseases of the biliary tract;

- pregnancy;

- breastfeeding period;

- children's age up to 12 years;

- Hypersensitivity to the drug.

Precautions should be given to patients with gastroesophageal reflux disease (GERD).

Drug interactions

With simultaneous use of the drug with other drugs that depress the central nervous system (including hypnotic drugs, antihypertensive drugs of central action, analgesics), may increase the effect on the central nervous system (may require dose adjustment).

Pregnancy and Lactation

The use of the drug during pregnancy and lactation is contraindicated.

Special instructions

In patients with GERD, symptoms may worsen.

If during the use of the drug symptoms persist or worsen, you should consult with your doctor.

Do not use the drug continuously for more than 1.5-2 months.

Influence on ability to drive motor transport and control mechanisms

During the period of drug treatment, care should be taken when performing potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (driving, working with moving mechanisms, the work of the dispatcher, the operator).


Symptoms: a single dose of 20 g of rhizomes with valerian roots (approximately 103 tab.) Can cause a feeling of fatigue, stomach cramps, a feeling of tightness in the chest, dizziness, hand tremor, dilated pupils that can pass on their own within 24 hours

Treatment: gastric lavage is recommended; symptomatic therapy is carried out if necessary.

With symptoms of overdose, the patient should consult a doctor.

  • Brand name: Persen
  • Active ingredient: Valerian root extras. Melissa Lek. herbs extras, mint leaves extras
  • Dosage form: pills, coated.
  • Manufacturer: Sandoz
  • Country of Origin: Switzerland

Studies and clinical trials of Persen (Click to expand)

  1. Comment on the minimum stable slug length
  2. Application of Schmidt's method to the calculation of spalding's function and of the skin-friction coefficient in turbulent flow
  3. The transfer of heat across a turbulent boundary layer at very high prandtl numbers
  4. Progress in Heat and Mass Transfer: Vol. 2, Eckert presentation volume. Pergamon Press, Oxford (1969). 499 pp, £12
  5. Boundary layer theory: L. N. Persen, 212 pp., Tapir, £3.30
  6. Stratified gas-liquid flow in downwardly inclined pipes
  7. Concepts of turbulence and C.F.D. applications
  8. The round thermal jet: undisturbed and in cross-flow
  9. On the stability of stratified flow and its transition to other flow regimes
  10. Einiges über die Grundlage der Berechnung von Wasserschlössern
  11. Satellitenbewegung mit Reibung
  12. R. S. Brand and L. N. Persen, Implications of „the Law of the Wall” for Turbulent Boundary Layers. (Acta Polytechnica Scandinavica, Physics including Nucleonics Series, No. 30) 61 S. Trondheim 1964. Preis brosch. Sw. Kr. 10.00
  13. L. N. Persen, Heat-transfer through Turbulent Layers at Arbitrary Prandtl-number. (Acta Polytechnica Scandinavica, Physics including Nucleonics Series, No. 35) 47 S. Trondheim 1965. Preis brosch. Sw. kr. 10:00
  14. L. N. Persen, Über die Grundlage der Theorie für Wärmeübertragung durch turbulente Grenzschichten. (Acta Polytechnica Scandinavica, Physics Including Nucleonics Series, No 39) 24 S. Trondheim 1966. Preis brosch. Sw. kr. 10,00
  15. L. N. Persen, Die theoretische Unterlage für die analytische Beschreibung der Wellenausbreitung im Felsen. (Acta Polytechnica Scandinavica, Civil Engineering and Building Construction Series No 39) 126 S. Trondheim 1966. Sw. Kr. 20:00
  16. On the measurement of wall shear stress
  17. A note on the turbulent energy as a parameter of turbulent flow
  18. On the error function of a complex argument
  19. The effect of a standing sound field on a slow stream discharged from a porous wall
  20. Stratified two-phase flow in circular pipes
  21. Rock dynamics and geophysical exploration — textbook : PERSEN, LN ELSEVIER, AMSTERDAM. 1975, P276
  22. Registration of plant protection products in EPPO countries: current status and possible approaches to harmonization
  23. De invloed van de stand van het lichaam op de intra-abdominale druk bij persen (Valsalva-manoeuvre)

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