Phenindione

Withacute myocardial infarction On the 1st day, 2-4 g intravenously are administered, followed by drip infusion of 8-16 g in 200 ml of 5% glucose solution for 2 hours. times / day On the 3rd day, 2 g / d drip is prescribed 2 times / day.
If necessary, a course of drug infusion of 2 g 2 times / day can be performed for 6 days.
Withchronic heart failure administered IV the drip 1-2 g 2 times / day for 10-14 days.
Withintraoperative myocardial ischemia the drug is administered as part of a conventional cardioplegic solution in the amount of 3 g per 1 liter. Neotone is added to the solution immediately prior to administration. It is recommended to conduct a course of infusion of the drug 2 g 2 times / day for 3-5 days prior to surgery, and within 1-2 days after surgery.
With the possibility of developmentintraoperative limb ischemia It is recommended to introduce 2-4 g of the drug intravenously before the operation with subsequent infusion of 8-10 g in a 5% glucose solution during the operation and the reperfusion period.

Data on the safety and efficacy of the drug Neoton during periods of pregnancy and lactation (breastfeeding) are not provided.

The drug should be administered as soon as possible after the onset of signs of ischemia, which provides a more favorable prognosis of the disease.
Neotone is not used for emergency correction of disorders of the heart.