Phosphonciale®
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Clinical Pharmacology
Phosphontsiale - a combined drug for the treatment of diseases of the liver and biliary tract. Reproduces the clinical and pharmacological effects of the components it contains - the “essential” phospholipids and the amount of flavolignans (in terms of silibinin) of milk thistle.
Phosphontsiale - hepatoprotective agent, normalizes the metabolism of lipids, proteins and phospholipids; stimulates protein synthesis; promotes the activation and protection of phospholipid-dependent enzyme systems, improves the functional state of the liver and its detoxification function, contributes to the preservation and restoration of the structure of hepatocytes; inhibits the formation of connective tissue in the liver.
Indications
In the complex therapy:
- hepatitis (acute and chronic of various genesis),
- fatty degeneration of the liver of various origins (diabetes, chronic infections),
- toxic hepatitis, alcoholic hepatitis,
- liver cirrhosis, hepatic coma, preeclampsia, radiation sickness,
- psoriasis (as adjuvant therapy),
- poisoning, drug intoxication, liver dysfunction in other somatic diseases
Composition
1 capsule contains:
Active substances: C100 lipoid 200 mg (in terms of phosphatidylcholine 188 mg), silymar - 70 mg (including silybin 50 mg);
Excipients: colloidal silicon dioxide (aperperl 300), povidone (collidon 90 F), calcium phosphate dihydrate, magnesium stearate, trehalose dihydrate;
gelatin capsule capsule auxiliaries: gelatin, titanium dioxide, ponso 4R, quinoline yellow.
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Dosage and Administration
With hepatitis of various etiologies - by mouth, 2 capsules 2 to 3 times a day with meals, swallowing whole, washed down with enough water. The course of treatment is at least 3 months; if necessary, the course of treatment can be continued or repeated. For viral hepatitis (especially for hepatitis B and C), take 2 capsules before or during meals 2 to 3 times a day, the course of treatment can be extended to 12 months.
With psoriasis (as part of complex therapy) - 1 - 2 capsules 3 times a day, the course of treatment is from 14 to 40 days.
In case of preeclampsia (preeclampsia with predominant liver damage, hepatosis, HELLP syndrome) - 2 - 3 capsules 2 - 3 times a day. The course of treatment is from 10 to 30 days.
With cirrhosis of the liver 2 capsules 2 to 3 times a day, a course of treatment for at least 3 months (depending on the severity of the process).
Poisoning, drug intoxication - 2 capsules 2 - 3 times a day, the course of treatment up to 30 - 40 days.
For preventive purposes (for example, people employed in hazardous occupations associated with the risk of being exposed to ionized radiation) the drug can be used 1 capsule 2 to 3 times a day for 1–3 months.
Adverse reactions
- Nausea,
- gastralgia,
- allergic reactions.
Contraindications
Hypersensitivity to phosphonciale components.
- Brand name: Phosphonciale
- Active ingredient: Milk thistle fruit extract, phospholipids
- Dosage form: Capsules
- Manufacturer: Canonpharma
- Country of Origin: Russia