Polygynax®
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Clinical Pharmacology
Polygynax Virgo has a bactericidal effect on gram-positive (Staphylococus aureus, Corynebacteria, etc.) and Gram-negative microorganisms (Enterococus faecium, Enterobacter aerogenes, Escherichia coli, Hemophilus influenzae, Proteus vulgaris, Klebsiella pneumoniae, myco-jerry, in-jerry, Istha, Istherophilus influenzae, Heleophilus influenzae, Proteus vulgaris, Klebsiella pneumonia, Myco-arteries, in-jerry, in-jones. It has a fungicidal effect on pathogenic fungi, especially yeast-like genus Candida albicans, Cryptococcus, Hystoplasma. Improves trophic processes in the vaginal mucosa.
Indications
Treatment.
- non-specific, fungal, mixed vaginitis, vulvovaginitis and cervicovaginitis;
Prevention.
- before surgical intervention in the genital area;
- before intrauterine diagnostic procedures.
Composition
Active substances:Neomycin sulfate 35 000 IU, Polymyxin B sulfate 35 000 IU, Nystatin 100 000 IU;
Excipients:hydrogenated soybean oil, dimethicone 1000, Tephos 63: palmitic esters and stearic esters.
The composition of the capsule shell:gelatin, glycerol, dimethicone 1000, purified water.
Polygynax® is marketed under different brands and generic names, and comes in different dosage forms:
Brand name | Manufacturer | Country | Dosage form |
---|---|---|---|
Polygynax Virgo | Innotech International | France | emulsion |
Polygynax | Innotech International | France | vaginal capsules |
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Dosage and Administration
For intravaginal administration. One capsule of Poliginax Virgo after evening dressing, before bedtime. Having cut the pointed end, and, slightly pressing the capsule, enter the contents of the capsule into the vagina. After injection of the drug into the vagina, the capsule is thrown into the trash. The course of treatment is 6 days. In order to prevent the drug is used for 6 days.
In case of skipping the drug, it is necessary to resume treatment at the usual dose.
Adverse reactions
Allergic reactions to the components of the drug. With prolonged use possible systemic manifestation of side effects of aminoglycosides, increasing in cases of renal failure.
Contraindications
Hypersensitivity to the drug.
Drug interactions
Not recommended for use in combination with spermicides, as may decrease the activity of the drug.
Pregnancy and Lactation
The patient should be informed that it is not recommended to use the drug during pregnancy without consulting a doctor.
It is necessary to avoid the use of the drug during breastfeeding.
Special instructions
Special instructions. The drug is designed specifically for use in girls and adolescent girls. Terms of the drug should be limited to prevent the formation of resistance to it of individual pathogens and the risk of reinfection. In case of kidney failure, consult a doctor. During treatment, it is necessary to refrain from using vaginal tampons. You should not interrupt the course of treatment during menstruation.
- Brand name: Polygynax
- Active ingredient: Neomycin, Nystatin, Polymyxin B
- Dosage form: Suppositories