Polymuramyl
Combiotech NPK
1379 Items
2019-09-19
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Clinical Pharmacology
Immunostimulating agent.
Polymuramyl is a natural immunostimulant. It enhances the absorption of bacteria and the killing of bacteria by phagocytic cells. This increases the ability of monocytes, macrophages and dendritic cells to produce cytokines (interleukin-12, tumor necrosis factor-α, granulocyte-macrophage colony-stimulating factor, etc.), activating cellular and humoral immunity. Polymuramyl enhances antibody synthesis and increases the functional activity of natural killer cells, which play an important role in antiviral and antitumor immunity. Polymuramyl has no teratogenic, embryotoxic, mutagenic and carcinogenic properties.
Indications
Polymuramil is used in adults simultaneously with antibacterial drugs in complex therapy:
- secondary immunodeficiency states, manifested in the form of chronic, sluggish, recurrent infectious-inflammatory processes of the skin, soft tissues;
- acute and chronic pyoderma, osteofolliculitis, sycosis, deep folliculitis, carbuncle, hydradenitis, furunculosis, abscesses, impetigo;
- for the treatment and prevention of surgical infections, including postoperative purulent-septic complications.
Composition
Active ingredient: Polimuramil - 200 mkg.
Excipients: water for injection 0.5 ml.
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Dosage and Administration
Polymuramil is administered intramuscularly (IM) at a dose of 200 mcg / 0.5 ml daily. In the case of secondary immunodeficiency states, 200 μg ip, once a day for 5 days as part of complex therapy with broad-spectrum antibiotics.
In the case of acute and chronic pyoderma in the acute stage (staphylodermia, streptoderma, mixed forms) - 200 mcg v / m, 1 time per day for 5 days as part of complex therapy with broad-spectrum antibiotics.
In the case of treatment and prevention of surgical infections in the acute stage, 200 mcg v / m, 1 time per day, 5 days as part of complex therapy (surgical treatment of a purulent focus, systemic antibacterial therapy, ligation with antiseptic and antibacterial agents of local action)
Adverse reactions
May cause a temporary increase in temperature to 37.5 aboutC, chills, soreness at the injection site.
Contraindications
Pregnancy, lactation, children under 18 years.
Drug interactions
The drug is compatible with all antimicrobial and anti-inflammatory drugs.
Special instructions
The drug does not affect the ability to drive vehicles and other mechanisms.
Overdosage
In case of overdose, the temperature may rise, and at febrile temperatures, symptomatic treatment should be carried out.
- Brand name: Polymuramyl
- Active ingredient: Polymuramyl
- Manufacturer: Combiotech NPK
- Country of Origin: Russia
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