Buy Potassium iodide pills 100 mcg 112 pcs
  • Buy Potassium iodide pills 100 mcg 112 pcs

Potassium iodide

PFK Obnovlenie
569 Items
2019-09-19
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Clinical Pharmacology

Prevention and treatment of endemic goiter. Prevention of relapse of goiter during the period of complex treatment with thyroid hormone drugs.

Indications

Prevention and treatment of endemic goiter. Prevention of relapse of goiter during the period of complex treatment with thyroid hormone drugs.

Composition

Active ingredient - potassium iodide

Potassium iodide is marketed under different brands and generic names, and comes in different dosage forms:

Brand nameManufacturerCountryDosage form
Potassium iodide PFK Obnovlenie Russia pills
Potassium iodide pills PFK Obnovlenie Russia pills
Potassium iodide Obolensky OP Russia pills
Microiodide Tatkhimpharmpreparaty Russia pills
Jodbalance Merck KGaA Germany pills
Yodomarin Berlin-Chemie/Menarini Germany pills

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Potassium iodide

Dosage and Administration

When determining the required dose of the drug, it is necessary to take into account regional and individual characteristics of iodine intake from food. This is especially important when prescribing the drug to newborns and children under 4 years of age.

Prevention of iodine deficiency disorders:

Newborns and children: 50-100 mcg of iodine per day (½ − 1 tablet of the drug Potassium iodide 100 mcg);

Adolescents and adults: 100-200 mcg of iodine per day (1 tablet of potassium iodide 100 mcg or 1 tablet of potassium iodide 200 mcg);

During pregnancy and during breastfeeding: 100-200 mcg of iodine per day (1 tablet of the drug Potassium iodide 100 mcg or 1 tablet of the drug Potassium iodide 200 mcg).

Prevention of relapse of goiter after its surgical removal or after completion of the treatment of goiter with thyroid hormone drugs:

100-200 mcg of iodine daily (1 tablet of the drug Potassium iodide 100 mcg or 1 tablet of the drug Potassium iodide 200 mcg).

Treatment of euthyroid goiter

Newborns and children: 100-200 mcg of iodine per day (1 tablet of potassium iodide 100 mcg or 1 tablet of potassium iodide 200 mcg);

Teens and young adult patients: 200 mcg iodine per day (2 pills of the drug Potassium iodide 100 mcg or 1 tablet of the drug Potassium iodide 200 mcg).

The daily dose of the drug should be taken in one step, after eating, with a sufficient amount of liquid. When prescribing the drug to newborns and children up to 3 years old, it is recommended to dissolve the tablet in a small amount (1 tablespoon) of boiled water at room temperature.

The use of the drug for prophylactic purposes is carried out for, as a rule, several months or years, and often during the whole life. For the treatment of goiter in newborns in most cases 2-4 weeks is enough; children, adolescents and adults usually need 6-12 months or more. The duration of treatment is determined by the doctor.

Adverse reactions

Allergic reactions are rare: skin rash, angioedema.

Contraindications

Potassium iodide should not be taken with hypothyroidism, unless the development of the latter is caused by a pronounced iodine deficiency.

Administration of the drug should be avoided with radioactive iodine therapy, in the presence or suspicion of thyroid cancer.

Since the drug contains lactose monohydrate, it is not recommended for patients with rare hereditary diseases associated with galactose intolerance, lactase deficiency or glucose-galactose malabsorption.

Drug interactions

With simultaneous high-dose therapy with iodine and potassium-sparing diuretics, hyperkalemia may develop, with lithium preparations - the development of goiter and hypothyroidism. Perchlorate and thiocyanate competitively inhibit iodine uptake by the thyroid gland, and TSH stimulates.

Antithyroid drugs weaken the effect (mutually).

Pregnancy and Lactation

In pregnancy, use is possible only in recommended doses, because iodine penetrates the placental barrier and can cause the development of hypothyroidism and goiter in the fetus.

Iodine is excreted in breast milk. When used in the mother during lactation (breastfeeding) in doses of more than 1 mg / day, there is a risk of developing hypothyroidism in the infant.

Special instructions

During therapy, patients with renal insufficiency may develop hyperkalemia.

Overdosage

With the appointment of the drug in a dose of more than 150 mg per day for patients with foci in the thyroid gland with functional autonomy, the development of iodine-induced hyperthyroidism is possible.

During therapy with high doses of iodine (more than 1,000 mcg per day), iodine-induced goiter and hypothyroidism may develop in some cases.

Chronic overdose can lead to the phenomenon of “iodism”: metallic taste in the mouth, swelling and inflammation of mucous membranes (rhinitis, conjunctivitis, gastroenteritis, bronchitis), acne, dermatitis, swelling of the salivary glands, fever, irritability.

Treatment: in case of chronic overdose, it is recommended to stop using the drug.With the development of iodine-induced hyperthyroidism, it is recommended to discontinue use of the drug and prescribe therapy with anti-thyroid agents. In severe cases, it is necessary to conduct intensive therapy, plasmapheresis or thyroidectomy.

With the development of hypothyroidism, it is recommended to discontinue the use of the drug and prescribe therapy with iodine-containing thyroid hormones.

  • Active ingredient: Potassium iodide

Studies and clinical trials of Potassium iodide (Click to expand)

  1. Copper(I) iodide catalyzed polycondensation of p-xylylene dibromide and potassium carbonate to give poly[(p-xylylene carbonate)-co-(p-xylylene oxide)]
  2. Selective Oxidation of Aromatic Amines to Nitro Derivatives using Potassium Iodide-tert-Butyl Hydroperoxide Catalytic System
  3. Synthesis of 3H-Quinazolin-4-ones and 4H-3,1-Benzoxazin-4-ones via Benzylic Oxidation and Oxidative Dehydrogenation using Potassium Iodide-tert-Butyl Hydroperoxide
  4. Experiments on the Scattering of Molecular Beams for the Study of Reactions of Potassium with Methyl Iodide, Hydrogen Bromide, and Bromine
  5. A Ternary Crown Ether “Supercomplex”: X-Ray Structure Analysis of the 1:1:1 Adduct of Dibenzo-[18]-Crown-6, Potassium Iodide, and Thiourea
  6. The effect of administration of thyroid substance, of potassium iodide, and of extirpation of the greater portion of the thyroid gland on the epidermis of the guinea-pig
  7. Determination of iodide using flow injection with acidic potassium permanganate chemiluminescence detection
  8. Calorimetric studies of the interactions of guanidinium hydrochloride and potassium iodide with model amides in aqueous solution
  9. Nadolol and potassium iodide in combination in the surgical treatment of thyrotoxicosis
  10. The Photochemistry of Aqueous Solutions of Potassium Iodide Containing N2O
  11. ChemInform Abstract: Cathodic Generation and Oxidation of Lead Zintl Ion Pb4-9 in Potassium Iodide Solutions in Liquid Ammonia.
  12. ChemInform Abstract: Synthesis of Homoallylic (But-3-enylic) Alcohols from Aldehydes with Allylic Chlorides, Tin(II) Chloride and Potassium Iodide in Water.
  13. ChemInform Abstract: Facile Formation of Samarium(III) Selenolates from Potassium Iodide Catalyzed Reaction of Samarium Metal and Diselenides, and Their Application in Synthesis of Selenoesters.
  14. ChemInform Abstract: Claisen Rearrangement of Allyloxyanthraquinones with Silver/Potassium Iodide in Acetic Acid as a New and Efficient Reagent.
  15. ChemInform Abstract: Reactions of Alkynes with Iodine and Potassium Iodide in Acetic Acid in the Presence of Nitrates. Simple Synthesis of 1-Iodo-2-nitroalkenes.
  16. ChemInform Abstract: Copper(I) Iodide Promoted Hydroxylation onto the Lithium or Potassium Enolate of Lactones and Lactams.
  17. Regioselective Oxyiodination of Aromatic Compounds Using Potassium Iodide and Oxone®.
  18. Highly Selective Iodination of Phenols Using Potassium Iodide and Benzyltriphenylphosphonium Peroxymonosulfate.
  19. Potassium Iodide Catalyzed Monoalkylation of Anilines under Microwave Irradiation.
  20. Direct Iodination of Aromatic Compounds with Polyvinylpyrrolidone Supported Hydrogen Peroxide (PVP-H2O2) and Potassium Iodide or Molecular Iodine.
  21. Novel C—C Bond Cleavage from Arylacetonitriles in Alcohols to Aryl Carboxylic Esters Using Potassium Iodide and Catalytic Amount of Samarium.
  22. Conversion of Glycals to 1-Azido-2-iodo Sugars Using N-Iodosuccinimide/Sodium Azide or Potassium Iodide/Oxone Reagent Systems: Application in the Synthesis of Methyl N-Acetyl-α-D-lividosaminide (IX).
  23. ChemInform Abstract: Mild and Efficient Deoxygenation of Sulfoxides to Sulfides with Triflic Anhydride/Potassium Iodide Reagent System.
  24. ChemInform Abstract: Iodination of Aromatic Compounds Using Potassium Iodide and Hydrogen Peroxide.

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