Buy Milgamma solution 2 ml ampoules 5 pcs
  • Buy Milgamma solution 2 ml ampoules 5 pcs

Pyridoxine, Thiamine, Cyanocobalamin, Lidocaine

Verwag Pharma
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Clinical Pharmacology

MILGAMMA - a complex of vitamins of group B. Neurotropic vitamins of group B have a beneficial effect on inflammatory and degenerative diseases of the nerves and the motor apparatus. Contribute to increased blood flow and improve the functioning of the nervous system.

Thiamine (vitamin B1) plays a key role in carbohydrate metabolism, as well as in the Krebs cycle, with subsequent participation in the synthesis of TPP (thiamine pyrophosphate) and ATP (adenosine triphosphate).

Pyridoxine (vitamin B6) is involved in the metabolism of protein and, in part, in the metabolism of carbohydrates and fats.

The physiological function of both vitamins is the potentiation of the action of each other, manifested in a positive effect on the neuromuscular and cardiovascular systems. With a deficiency of vitamin B6, widespread states of deficiency quickly stop after the introduction of these vitamins.

Cyanocobalamin (vitamin B12) is involved in the synthesis of the myelin sheath, stimulates hematopoiesis, reduces pain associated with damage to the peripheral nervous system, stimulates nucleic acid metabolism through activation of folic acid.

Lidocaine is a local anesthetic that causes all types of local anesthesia (terminal, infiltration, conduction).


As a pathogenetic and symptomatic agent in the complex therapy of diseases and syndromes of the nervous system of various origins:

- neuralgia, neuritis;

- paresis of the facial nerve;

- retrobulbar neuritis;

- ganglionitis (including shingles);

- plexopathy;

- neuropathy;

- polyneuropathy (diabetic, alcoholic);

- nighttime muscle cramps, especially in older age groups;

- neurological manifestations of spinal osteochondrosis;

- radiculopathy;

- lumboischialgia;

- musculo-tonic syndromes.


1 ampoule (2 ml) contains: thiamine hydrochloride 100 mg, pyridoxine hydrochloride 100 mg, cyanocobalamin hydrochloride 1000 mcg

Pyridoxine, Thiamine, Cyanocobalamin, Lidocaine is marketed under different brands and generic names, and comes in different dosage forms:

Brand nameManufacturerCountryDosage form
Milgamma Verwag Pharma Germany solution
CompligamV Sotex Russia ampoules
Combilipen Pharmstandard Ufavita Russia solution

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Pyridoxine, Thiamine, Cyanocobalamin, Lidocaine

Dosage and Administration

The drug is administered intramuscularly.
When expressed manifestations of 2 ml daily for 5-7 days, then 2 ml 2-3 times a week for 2 weeks; in mild cases, 2 ml 2-3 times a week for 7-10 days.
Duration is determined by the doctor individually, depending on the severity of symptoms of the disease, but should not exceed two weeks. For maintenance therapy, it is recommended to take oral forms of vitamins of group B.

Adverse reactions

Allergic reactions (skin reactions in the form of itching, urticaria), increased sweating, tachycardia, acne appears, difficulty breathing, angioedema, anaphylactic shock.


Hypersensitivity to the components of the drug Combilipen, severe and acute forms of decompensated heart failure. Pregnancy and lactation.

Drug interactions

Levodopa reduces the effect of therapeutic doses of vitamin B6. Vitamin B12 is incompatible with heavy metal salts. Ethanol dramatically reduces the absorption of thiamine. While taking the drug, it is not recommended to take multivitamin complexes that include vitamins of group B.

Special instructions

Combilipen contains benzyl alcohol. Do not assign children because of the content in the preparation of benzyl alcohol.


Symptoms: increased symptoms of side effects of the drug.

First aid: the appointment of symptomatic therapy.

  • Active ingredient: Pyridoxine, Thiamine, Cyanocobalamin, Lidocaine

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