Buy Relenza powder 5 mg/dose rotadiski 4 doses with diskhaler 5 pcs
  • Buy Relenza powder 5 mg/dose rotadiski 4 doses with diskhaler 5 pcs

Relenza® [Zanamivir]

GlaxoSmithKline
937 Items
2019-09-19
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$62.06
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Clinical Pharmacology

Relenza is an antiviral agent. Highly inhibits neuraminidase - a surface enzyme of the influenza virus, incl. all known subtypes of neuraminidase of influenza A virus, blocks the replication of influenza viruses A and B. It prevents the release of new virus particles from infected cells, the interaction of viruses with the surface of the epithelial cells of the respiratory tract and their infection.

Indications

Prevention and treatment of influenza A and B in adults and children over 5 years.

Composition

1 dose contains zanamivir 5 mg, as well as lactose as a filler.

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Relenza® [Zanamivir]

Dosage and Administration

Inhalation, using a special device "Relenza Diskhaler."
Treatment:
2 inhalations (5 mg x 2) 2 times a day for 5 days (maximum daily dose - 20 mg); treatment is recommended to begin within the first two days of the disease.
Prevention: 2 inhalations (5 mg x 2) 1 time per day for 10 days (maximum daily dose - 10 mg).

Adverse reactions

Very rarely - bronchospasm, shortness of breath, allergic reactions (including rash, urticaria, swelling of the face and the mucous membrane of the oropharynx).

Contraindications

Hypersensitivity to the drug.

Drug interactions

Do not combine with other inhaled drugs (including bronchodilators).

Pregnancy and Lactation

Contraindicated in the first trimester of pregnancy, in the second and third trimesters it is possible if the expected effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Special instructions

If bronchospasm develops, inhalation should be stopped immediately and consult a doctor. If you have a history of respiratory diseases accompanied by bronchospasm, you should carry bronchodilators (for example, salbutamol) during the entire period of treatment.

Overdosage

Accidental overdose is unlikely due to metered administration, route of administration and low bioavailability of the drug.
With inhalation use of 64 mg / day (more than 3 times the recommended daily dose), no side effects have been registered. Also, they are not registered with parenteral use of the drug Relenza at a dose of 1.2 g / day. within 5 days.

  • Brand name: Relenza
  • Active ingredient: Zanamivir
  • Dosage form: Powder for inhalation.
  • Manufacturer: GlaxoSmithKline
  • Country of Origin: Great Britain

Studies and clinical trials of Relief (Click to expand)

  1. Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities
  2. Synthesis of novel analogues of zanamivir as neuraminidase inhibitors
  3. Oseltamivir and zanamivir are effective for treating influenza, but preventive effects are unclear
  4. Determination of zanamivir in rat and monkey plasma by positive ion hydrophilic interaction chromatography (HILIC)/tandem mass spectrometry
  5. A comparison of the effectiveness of zanamivir and oseltamivir for the treatment of influenza A and B
  6. Oseltamivir, zanamivir and amantadine in the prevention of influenza: A systematic review
  7. Computational analysis and modeling the effectiveness of ‘Zanamivir’ targeting neuraminidase protein in pandemic H1N1 strains
  8. Scheduling workforce relief breaks in advance versus in real-time
  9. Two randomized, double-blind, placebo-controlled efficacy studies assessing the efficacy and speed of onset of pain relief of Panadol Advance® in post-surgical dental pain
  10. Judgments. Equitable Relief. Enforcement of Judgment for Advance Payments on Contract of Sale Repudiated by Buyer
  11. Advance relief under the Cape Town Convention
  12. Advance relief under the Cape Town Convention and its Aircraft Protocol: A comment on Gilles Cuniberti's interpretative proposal
  13. Pain Relief - From Analgesics to Alternative Therapies || Advance Delivery System Dosage Form for Analgesic, Their Rationale, and Specialty
  14. PCEA compared to continuous epidural infusion in an ultra-low-dose regimen for labor pain relief: a randomized study
  15. Modifications du relief cutané provoquées par le rayonnement ultra-violet
  16. Quasi-Contractual Relief under Executory Ultra Vires Contracts
  17. ECS Transactions [ECS Semiconductor Technology for Ultra Large Scale Integrated Circuits and Thin Film Transistors 3 - Hong Kong, China (June 26 - July 1, 2011)] - (Invited) Short Channel Effects and Drain Field Relief Architectures in Polysilicon TFTs
  18. Ultra-low-dose estradiol and norethisterone acetate: effective menopausal symptom relief
  19. PCEA Compared to Continuous Epidural Infusion in an Ultra-Low-Dose Regimen for Labor Pain Relief: A Randomized Study
  20. Effects of Ultra-Low-Dose Buprenorphine on Suicidal Ideation Confounded by Physical Pain Relief?
  21. Ultra–low-dose Naloxone as an Adjuvant to Patient Controlled Analgesia (PCA) With Morphine for Postoperative Pain Relief Following Lumber Discectomy
  22. On Residual Stress and Relief for an Ultra-Thick Cylinder Weld Joint Based on Mixed Hardening Model: Numerical and Experimental Studies
  23. Running shoes for relief of plantar pressure in diabetic patients
  24. Drainage Density and Relative Relief in Humid Steep Mountains with Frequent Slope Failure
  25. ChemInform Abstract: Novel Inhibitors of Influenza Sialidases Related to Zanamivir. Heterocyclic Replacements of the Glycerol Side-Chain.
  26. ChemInform Abstract: Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. Part 2. Crystallographic and Molecular Modeling Study of Complexes of 4-Amino-4H-pyran-6-carboxamides and Sialidase from Influenza Virus Types A and B.
  27. ChemInform Abstract: Sialidase Inhibitors Related to Zanamivir: Synthesis and Biological Evaluation of 4H-Pyran 6-Ether and Ketone.
  28. ChemInform Abstract: Sialidase Inhibitors Related to Zanamivir. Further SAR Studies of 4-Amino-4H-pyran-2-carboxylic Acid-6-propylamides.
  29. Synthesis and Antiinfluenza Virus Activity of 7-O-Alkylated Derivatives Related to Zanamivir.

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