Retinol

The use of the drug should be under the supervision of a physician. The drug is taken orally after a meal early in the morning or late in the evening.
1 drop of the drug from a dropper or an eye dropper contains retinol palmitate of about 3,300 IU.
1 mg of retinol palmitate corresponds to 1817 IU.
With mild to moderate avitaminosis
Therapeutic doses for adults with mild to moderate avitaminosis are up to 33,000 IU / day.
For children - 1000-5000 IU / day. depending on age.
For eye diseases
Assign an adult - 50000-100000 IU per day and at the same time 0.02 g of riboflavin.
In dermatology in the treatment of acne and ichthyosiform erythrodermia
In adults, 100000-300000 IU / day.
Children 5,000-10,000 IU / kg per day.
For skin diseases
Assign adults per day to 50,000-100,000 IU of retinol palmitate.
In Gastroenterology
At 50,000 IU per day.
Single doses of retinol palmitate should not exceed 50,000 IU for adults and 5,000 IU for children.
Daily doses for adults are 100,000 IU and 20,000 IU for children.

Contraindications

Hypersensitivity to the drug.
Hypervitaminosis A.
Pregnancy.
Cholelithiasis.
Chronic pancreatitis.
Acute inflammatory skin diseases.
Use with caution when:
Jade
Heart failure II-III Art.
Alcoholism.
Viral hepatitis.
Renal failure.
In old age.
In childhood.

Drug interactions

During long-term tetracycline therapy, it is not recommended to prescribe vitamin A (the risk of developing intracranial hypertension increases).
Salicylates and glucocorticosteroids reduce the risk of side effects.
Kolestiramin, Kolestipol, mineral oils, neomycin reduce the absorption of vitamin A (may require an increase in dose).
Oral contraceptives increase the concentration of vitamin A in plasma.
Isotretinoin increases the risk of a toxic effect.
Vitamin E reduces toxicity, absorption, deposition in the liver and the use of vitamin A; high doses of vitamin E can reduce the supply of vitamin A in the body.
Weakens the effect of calcium preparations, increases the risk of hypercalcemia.