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Retinol acetate solution in oil has the effect of compensating for vitamin A deficiency. Regulation of vitamin A-dependent metabolic processes.
Hypovitaminosis A, infectious diseases (measles, dysentery, tracheitis, bronchitis, pneumonia); skin diseases (burns, frostbite, wounds, skin tuberculosis, hyperkeratosis, ichthyosis, psoriasis, pyoderma, some forms of eczema); eye diseases (retinitis pigmentosa, hemeralopia, xerophthalmia, keratomalacia, conjunctivitis); chronic enterocolitis, hepatitis.
1 ml of solution contains retinol acetate 3.44% -100000 IU
Retinol is marketed under different brands and generic names, and comes in different dosage forms:
|Brand name||Manufacturer||Country||Dosage form|
|Retinol Acetate||Vitamin A) (Marbiopharm||Russia||bottle|
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Dosage and Administration
The use of the drug should be under the supervision of a physician. The drug is taken orally after a meal early in the morning or late in the evening.
1 drop of the drug from a dropper or an eye dropper contains retinol palmitate of about 3,300 IU.
1 mg of retinol palmitate corresponds to 1817 IU.
With mild to moderate avitaminosis
Therapeutic doses for adults with mild to moderate avitaminosis are up to 33,000 IU / day.
For children - 1000-5000 IU / day. depending on age.
For eye diseases
Assign an adult - 50000-100000 IU per day and at the same time 0.02 g of riboflavin.
In dermatology in the treatment of acne and ichthyosiform erythrodermia
In adults, 100000-300000 IU / day.
Children 5,000-10,000 IU / kg per day.
For skin diseases
Assign adults per day to 50,000-100,000 IU of retinol palmitate.
At 50,000 IU per day.
Single doses of retinol palmitate should not exceed 50,000 IU for adults and 5,000 IU for children.
Daily doses for adults are 100,000 IU and 20,000 IU for children.
Hypersensitivity to the drug.
Acute inflammatory skin diseases.
Use with caution when:
Heart failure II-III Art.
In old age.
During long-term tetracycline therapy, it is not recommended to prescribe vitamin A (the risk of developing intracranial hypertension increases).
Salicylates and glucocorticosteroids reduce the risk of side effects.
Kolestiramin, Kolestipol, mineral oils, neomycin reduce the absorption of vitamin A (may require an increase in dose).
Oral contraceptives increase the concentration of vitamin A in plasma.
Isotretinoin increases the risk of a toxic effect.
Vitamin E reduces toxicity, absorption, deposition in the liver and the use of vitamin A; high doses of vitamin E can reduce the supply of vitamin A in the body.
Weakens the effect of calcium preparations, increases the risk of hypercalcemia.
- Active ingredient: Retinol
- Quantitative analysis of retinol and retinol palmitate in vitamin tablets using 1H-nuclear magnetic resonance spectroscopy
- Sample preparation for routine high-performance liquid chromatographic determination of retinol palmitate in emulsified nutritional supplements by solid-phase extraction using monosodium l-glutamate as dissolving agent
- Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography–atmospheric pressure chemical ionization–mass spectrometry
- Simultaneous determination of retinol acetate, retinol palmitate, cholecalciferol, α-tocopherol acetate and alphacalcidol in capsules by non-aqueous reversed-phase HPLC and column backflushing
- A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy
- Unoccluded Retinol Penetrates Human Skin In Vivo More Effectively Than Unoccluded Retinyl Palmitate or Retinoic Acid.
- Serum retinoic acid, retinol and retinyl palmitate levels in patients with lung cancer
- Determination of retinol, retinyl palmitate, and retinoic acid in consumer cosmetic products
- Allergic contact dermatitis from tocopheryl acetate (vitamin E) and retinol palmitate (vitamin A) in a moisturizing cream
- Protective role of melatonin and retinol palmitate in oxidative stress and hyperlipidemic nephropathy induced by adriamycin in rats
- Simultaneous determination of retinol, retinyl palmitate and β-carotene in rat serum treated with 7,12-dimethylbenz[a]anthracene andHypericum PerforatumL. by high-performance liquid chromatography with diode-array detection
- The effect of α tocopherol, all-trans retinol and retinyl palmitate on the non enzymatic lipid peroxidation of rod outer segments
- Characterization of Esterase and Alcohol Dehydrogenase Activity in Skin. Metabolism of Retinyl Palmitate to Retinol (Vitamin A) During Percutaneous Absorption
- HPLC determination of tocopherol, retinol, dehydroretinol and retinyl palmitate in tissues of lake char (Salvelinus namaycush) exposed to coplanar 3,3′,4,4′,5-pentachlorobiphenyl
- The effect of vitamin A on fusion of mouse palates. II. Retinyl palmitate, retinol, and retinoic acid in vitro
- Intestinal absorption of retinol and retinyl palmitate in the rat. Effects of tetrahydrolipstatin
- The effect of 3,4,3′,4′-tetrachlorobiphenyl on plasma retinol and hepatic retinyl palmitate hydrolase activity in female Sprague-Dawley rats
- Variations in pattern of regeneration from different proximo-distal levels of limbs in young frog tadpoles treated with retinol palmitate: I.A. Niazi and K.K. Sharma. Department of Zoology, University of Rajasthan, Jaipur 302004, India
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