Rhodiola
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Clinical Pharmacology
Rhodiola quadrifida - biologically active additive (BAA). It has an adaptogenic, anti-inflammatory, immunomodulatory and tonic effect. It is used for diseases of the female genitalia (dysmenorrhea, uterine myoma, cervical erosion, endometriosis, adnexitis, ovarian cysts, mastopathy); male genital diseases (prostatitis, prostate adenoma); in other areas (endocrine diseases, oncological diseases).
Rhodiola quadrifida (Rhodiola Cold) - Dietary Supplement (BAA); popular in folk medicine for female diseases of various kinds, for prostate adenoma in men, as well as for endocrine disorders and diseases of the thyroid gland.
The Rhodiola quadrifida has an adaptogenic, anti-inflammatory, tonic, hemostatic effect. Rhodiola quadrifida increases mental and physical performance, resistance to infectious diseases (has an immunomodulatory effect).
The multicomponent chemical composition of the Rhodiola quadrifida (glycoside salidrozide, anthocyanins, tannins, etc.) determines the multifunctional action. One of the main active ingredients of the Rhodiola quadrifida is the glycoside salidrozid contributes to the manifestation of oncoprotective, anti-inflammatory, anti-infective and adaptogenic properties of the plant, eliminating endocrine disorders in gynecological diseases, pathologies of the thyroid gland, adrenal glands. Anthocyanins cause a prophylactic and therapeutic effect in diseases of bacterial, viral, fungal etiology.
Indications
The Rhodiola quadrifida is recommended as a dietary supplement to food - an additional source of glycosides (salidroside).
The Rhodiola quadrifida is used for female genital diseases (gynecological diseases):
dysmenorrhea (menstrual disorders);
uterine fibroids;
cervical erosion;
endometriosis;
adnexitis;
polycystic and ovarian cysts;
mastopathy.
The Rhodiola quadrifida is used for diseases of the male genitalia:
prostatitis;
BPH;
oligospermia;
weakening of potency.
Other uses:
infectious and inflammatory diseases;
endocrine diseases, thyroid diseases;
blood diseases, anemia, leukemia;
oncological diseases (tumors of various etymologies).
Composition
Purified water, extract of rhizomes with roots of rhodiola four-membered (Rhodiola quadrifida), colloidal silver, antioxidant: citric acid (E330), ascorbic acid (E300), preservative: sodium benzoate (E211), sweetener: Aspasvit-TC200 (contains E953, E954, E955).
Rhodiola is marketed under different brands and generic names, and comes in different dosage forms:
Brand name | Manufacturer | Country | Dosage form |
---|---|---|---|
Rhodiola quadrifida | ResortMedservis | Russia | solution |
Rhodiola extract liquid | Vifiteh | Russia | liquid extract |
Rhodiola quadrifida | Evalar | Russia | Other |
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Dosage and Administration
1 teaspoon (1.5 g) of herbal tea pour 1 cup (200 ml) of boiling water, leave for 15-20 minutes, strain, take for adults 1/3 cup 3 times a day with meals in the morning.
Individual intolerance to the components, pregnancy, breastfeeding, increased nervous excitability, insomnia, high blood pressure, impaired cardiac activity, marked atherosclerosis.
Special instructions
Before applying the Rhodiola quadrifida, you should consult with your doctor.
- Brand name: Rhodiola quadrifida
- Active ingredient: Rhodiola four-cut
- Manufacturer: ResortMedservis
- Country of Origin: Russia
Studies and clinical trials of Rhodiola (Click to expand)
- Demonstration of additional benefit in adding lenalidomide to azacitidine in patients with higher-risk myelodysplastic syndromes
- Lenalidomide, cyclophosphamide and dexamethasone (CRd) for newly diagnosed multiple myeloma: Results from a phase 2 trial
- Rapid response of plasmacytomas to lenalidomide plus low-dose dexamethasone therapy in a patient with relapsed multiple myeloma
- Inflammation, TNFα and endothelial dysfunction link lenalidomide to venous thrombosis in chronic lymphocytic leukemia
- Lenalidomide-associated pneumonitis in patients with plasma cell dyscrasias
- Lenalidomide for aggressive B-cell lymphoma involving the central nervous system?
- Drug interaction between lenalidomide and itraconazole
- Pachymeningeal involvement in POEMS syndrome: Dramatic cerebral MRI improvement after lenalidomide therapy
- Evaluation of the developmental toxicity of lenalidomide in rabbits
- Phase II study of lenalidomide in patients with metastatic renal cell carcinoma
- Combined pegylated liposomal doxorubicin and bortezomib is highly effective in patients with recurrent or refractory multiple myeloma who received prior thalidomide/lenalidomide therapy
- Thromboembolic events with lenalidomide-based therapy for multiple myeloma
- The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities : How does it relate to the original lenalidomide experience in MDS?
- Results of a multicenter, randomized, double-blind, dose-evaluating phase 2/3 study of lenalidomide in the treatment of metastatic malignant melanoma
- Results of a multicenter, randomized, double-blind phase 2/3 study of lenalidomide in the treatment of pretreated relapsed or refractory metastatic malignant melanoma
- ChemInform Abstract: Prolyl Endopeptidase Inhibitors from the Underground Part of Rhodiola sachalinensis.
- Rhodiolosides A—E, Monoterpene Glycosides from Rhodiola rosea
- ChemInform Abstract: Bioactive Constituents from Chinese Natural Medicines. Part 29. Monoterpene and Monoterpene Glycosides from the Roots of Rhodiola sachalinensis.
- ChemInform Abstract: Bioactive Constituents from Chinese Natural Medicines. Part 30. Reinvestigation of Absolute Stereostructure of (-)-Rosiridol: Structures of Monoterpene Glycosides, Rosiridin, Rosiridosides A (Ia), B (Ib) and C (Ic), from Rhodiola sachalinensis.
- ChemInform Abstract: Revised Absolute Stereochemistry of Rhodiolosides A—D, Rhodiolol A and Sachalinol A from Rhodiola rosea.
- Comparison of xanthine oxidase-inhibiting and free radical-scavenging activities between plant adaptogens of Eleutherococcus senticosus and Rhodiola rosea
- Determination of salidroside and tyrosol in Rhodiola by capillary electrophoresis with graphene/poly(urea-formaldehyde) composite modified electrode
- Comparison of electrospray ionization and atmospheric pressure chemical ionization techniques in the analysis of the main constituents from Rhodiola rosea extracts by liquid chromatography/mass spectrometry
- Preparative purification of salidroside from Rhodiola rosea by two-step adsorption chromatography on resins
- Flavonol glycosides from Rhodiola crenulata
- Identification of flavonoids of Rhodiola rosea by liquid chromatography-tandem mass spectrometry
- Acetylcholinesterase inhibitory-active components of Rhodiola rosea L.
- Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities
- Simultaneous determination of pharmacologically active ingredients in Rhodiola by capillary chromatography with electrochemical detection
- Simultaneous determination of salidroside and tyrosol in extracts of Rhodiola L. by microwave assisted extraction and high-performance liquid chromatography
- Characterization of glycosyltransferases responsible for salidroside biosynthesis in Rhodiola sachalinensis
- Anti-inflammatory activity of caffeic acid phenethyl ester (CAPE) extracted from Rhodiola sacra against lipopolysaccharide-induced inflammatory responses in mice
- The efficacy and safety of lenalidomide plus dexamethasone in relapsed and/or refractory multiple myeloma patients with impaired renal function
- Interim report of a phase 2 clinical trial of lenalidomide for T-cell non-Hodgkin lymphoma
- Tumor flare reaction associated with lenalidomide treatment in patients with chronic lymphocytic leukemia predicts clinical response
- Kinetic and technical studies on large-scale culture of Rhodiola sachalinensis compact callus aggregates with air-lift reactors
- RP-HPLC determination of phenylalkanoids and monoterpenoids in Rhodiola rosea and identification by LC-ESI-TOF
- Erratum: RP-HPLC determination of phenylalkanoids and monoterpenoids in Rhodiola rosea and identification by LC-ESI-TOF
- LC/MS/MS identification of glycosides produced by biotransformation of cinnamyl alcohol in Rhodiola rosea compact callus aggregates
- ChemInform Abstract: Bioactive Constituents of Chinese Natural Medicines. Part 4. Rhodiolae Radix. Part 2. On the Histamine Release Inhibitors from the Underground Part of Rhodiola sacra (PRAIN ex HAMET) S. H. Fu (Crassulaceae): Chemical Structures of Rhodiocyanoside D and Sacranosides A and B.
- ChemInform Abstract: Rhodiola rosea L.: Traditional and Biotechnological Aspects of the Isolation of Medicinal Drugs