Buy Hyalur syringe 3 ml syringe 1pc
  • Buy Hyalur syringe 3 ml syringe 1pc

Sodium Hyaluronate, Chondroitin Sodium Sulfate

K.O.Romparm Company S.R.L.
541 Items
2019-09-19
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$465.69
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Clinical Pharmacology

Hyalur CS is designed to replenish the volume and restore the viscosity of synovial fluid in the joints. Hyalur CS is dissolved in synovial fluid, providing a beneficial effect. It undergoes local transformations in the joint cavity, it rationalizes the properties of the synovial fluid, returning its lubricating and shock-absorbing functions. The highest concentrations of hyaluronic acid in studies were found in synovial fluid and the articular capsule, lower concentrations - in the synovial membrane, ligaments and
adjacent muscles, excretion is mainly carried out by the kidneys.
The introduction of a single injection is recommended, the effect lasts at least for 6 months. This osteoarthritis therapy is generally accepted, safe and effective.
When administered once with CS hyalur, it restores the lubricating and depreciation properties of synovial fluid, has a pronounced and long-term analgesic effect and significantly reduces the limitation of mobility of joints.
Sodium hyaluronate is obtained by bacterial fermentation.

Indications

- for symptomatic treatment of mild, moderate or severe osteoarthritis;
- with pain and limited mobility caused by degenerative-dystrophic or post-traumatic changes of the knee, hip and other synovial joints;
- to relieve pain after arthroscopy (use is possible not earlier than 1 week after the intervention).

Composition

1 prefilled syringe with Hyalur CS

Sodium Hyaluronate 60.00 mg
Chondroitin sodium sulfate 90.00 mg
Sodium Chloride 10.50 mg
Sodium dihydrogen phosphate monohydrate 1.35 mg
Disodium phosphate dodecahydrate 15.15 mg
Sodium hydroxide and / or hydrochloric acid (for pH adjustment)
Water for injection up to 3.00 ml

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Sodium Hyaluronate, Chondroitin Sodium Sulfate

Dosage and Administration

Hyalur CS is intended for intraarticular injection.
The solution should not be injected outside the joint cavity, as well as in patients with infections or skin diseases in the area of ​​the injection.
Intra-articular injection should be administered by specialists who have been trained in the technique of intra-articular injection and should be made under aseptic conditions in medical institutions.
Perhaps the use of local anesthetics before intraarticular injection, for example, subcutaneous injection of lidocaine.
It is necessary to properly disinfect the injection site (use a solution of 70% alcohol or other disinfectants). Disinfectants containing quaternary ammonium salts (for example, benzalkonium chloride) should not be used, since precipitation is possible.
Before the introduction of Hyaluroma CS, fluid should be removed from the joint cavity.
It is recommended that arthrocentesis be performed before the solution is injected.
After removing the protective cap from the syringe tip, attach to the syringe
sterile needle. Usually, a needle with a size of 0.8x40 mm (21G) is used for the knee joint, for other joints we recommend using a needle of the required size (from 17G to 22G) depending on the joint.
Hyalur CS is injected into the joint in volume, depending on the size of the joint. The joint cavity should not be overloaded.
Each pre-filled syringe is intended for single use. The contents of the syringe should be used immediately after opening. Unused completely solution is not subject to storage and should not be re-sterilized.
After the injection of Hyaluroma CS, the patient is advised to adhere to a gentle regimen and avoid excessive or prolonged stress on the joints (for example, running or playing tennis) for 48 hours.

Adverse reactions

You may experience mild pain and swelling at the injection site.
The above symptoms are transient and usually disappear after 72 hours.

Contraindications

- the established hypersensitivity to the components of this medical device;
- the presence of active inflammatory or infectious processes in the joint;
- the presence of signs of active skin disease or skin infection in the area of ​​the intended injection;
- use in patients with an established diagnosis of an autoimmune disease or undergoing immunotherapy;
- use during pregnancy or lactation;
- age up to 18 years.

  • Brand name: Hyalur
  • Active ingredient: Sodium Hyaluronate, Chondroitin Sodium Sulfate
  • Dosage form: Transparent viscous solution from colorless to brown color in disposable hydrolytic class I glass syringes equipped with a Luer Lock-type needle fixation system, complete with a three-edged laser-sharpened needle. There is no graduation of the syringe; it is not required, since the contents of one syringe are used only once and are intended for only one patient.
  • Manufacturer: K.O.Romparm Company S.R.L.
  • Country of Origin: Romania

Studies and clinical trials of Sodium Hyaluronate, Chondroitin Sodium Sulfate (Click to expand)

  1. P176 Comparative trial on the efficacy of the treatment of osteoarthritis by intraarticular application of sodium hyaluronate and chondroitin sulfate vs. hylan GF-20
  2. P22 Cartilage regeneration. Chondrogenic induction by the effect of sodium hyaluronate and chondroitin sulfate
  3. Natural Course of Intraocular Pressure after Cataract Surgery with Sodium Chondroitin Sulfate 4%–Sodium Hyaluronate 3% (Viscoat)
  4. Effects of sodium-hyaluronate and glucosamine-chondroitin sulfate on remodeling stage of tenotomized superficial digital flexor tendon in rabbits: a clinical, histopathological, ultrastructural, and biomechanical study
  5. The Effect of Sodium Hyaluronate and Sodium Chondroitin Sulfate on the Coagulation System In Vitro
  6. Combined intravesical sodium hyaluronate/chondroitin sulfate therapy for interstitial cystitis/bladder pain syndrome: a prospective study
  7. The Effects of Sodium Hyaluronate, Chondroitin Sulfate, and Methylcellulose on the Corneal Endothelium and Intraocular Pressure
  8. The Effect of Sodium Hyaluronate, Chondroitin Sulfate, and Methylcellulose on the Corneal Endothelium and Intraocular Pressure: Reply
  9. The Effect of Sodium Hyaluronate, Chondroitin Sulfate, and Methylcellulose on the Corneal Endothelium and Intraocular Pressure
  10. Sodium hyaluronate and chondroitin sulfate replenishment therapy can improve nocturia in men with post-radiation cystitis: results of a prospective pilot study
  11. Effectiveness of intra-articular injections of sodium hyaluronate-chondroitin sulfate in knee osteoarthritis: a multicenter prospective study
  12. Erratum to: Effectiveness of intra-articular injections of sodium hyaluronate-chondroitin sulfate in knee osteoarthritis: a multicenter prospective study
  13. The Effect of Triamcinolone Acetonide, Sodium Hyaluronate, and Chondroitin Sulfate on Human Endothelial Cells: An in Vitro Study
  14. The effect of sodium hyaluronate–chondroitin sulfate combined solution on cartilage formation in osteochondral defects of the rabbit knee: an experimental study
  15. Effects of chondroitin sulfate and sodium hyaluronate on chondrocytes and extracellular matrix of articular cartilage in dogs with degenerative joint disease

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