Sulfadimidine

Inside, 1 g 4-6 times a day. With pneumonia and meningitis at the first dose - 2 g; children - at the rate of 0.1 g / kg at the first dose, then at 0.25 g / kg every 4, 6, 8 hours. Higher doses for adults: single - 2 g, daily - 7 g; for children up to 1 year old, daily - 0.15 g / kg, older than 1 year, daily - 0.1-0.15 g / kg. When dysentery is carried out 2 courses of treatment. The first course: 1 and 2 days - 1 g every 4 hours (only 6 g / day), 3 and 4 days - 1 g every 6 hours (4 g / day), 5 and 6 days - 1 g every 8 hours ( 3 g / day). After 5-6 days, the second course is carried out: 1 and 2 days - 1 g every 4 hours, at night - after 8 hours (5 g / day in total), 3 and 4 days - 1 g after 4 hours (4 g / day, do not give at night), 5 day - 3 g / day.

Contraindications

Hypersensitivity, inhibition of bone marrow hematopoiesis, chronic renal failure, hyperbilirubinemia in children (the risk of developing bilirubin encephalopathy), congenital deficiency of glucose-6-phosphate dehydrogenase, porphyria, azotemia, pregnancy, lactation.

Drug interactions

Reduces the effectiveness of bactericidal antibiotics acting only on fissile microorganisms (including penicillins and cephalosporins). Increases (mutually) hematotoxicity of chloramphenicol, thiamazole. Benzocaine, procaine reduce antimicrobial activity (PABA is released during hydrolysis). Ascorbic acid, hexamethylenetetramine increase the risk of crystalluria. NSAIDs, hypoglycemic drugs (sulfonylurea derivatives), phenytoin and coumarin anticoagulants increase the severity of side effects. Antacids reduce intestinal absorption. When toxoplasmosis may be combined with pyrimethamine. Myelotoxic drugs increase the hematotoxicity of the drug.

Pregnancy and Lactation

Special instructions

• Brand name: Sulfadimidine
• Active ingredient: Sulfadimidine
• Dosage form: pills are white or white with a slightly yellowish tinge, flat-cylindrical, with a chamfer and risk.
• Manufacturer: Irbit HFZ
• Country of Origin: Russia