Sulfasalazine
Krka dd Novo mesto AO
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Clinical Pharmacology
Sulfasalazine-EN has antimicrobial, anti-inflammatory effect.
Indications
- non-specific ulcerative colitis (treatment of exacerbations and maintenance therapy in remission);
- Crohn's disease (mild and moderate forms in the acute phase);
- rheumatoid arthritis;
- juvenile rheumatoid arthritis.
Composition
1 tab. contains Sulfasalazinee (coated with povidone) 500 mg.
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Dosage and Administration
Inside. On the first day of treatment, adults are prescribed in a dose of 500 mg 4 times / day; on the 2nd day - 1 g 4 times / day; on the 3rd and subsequent days - 1.5-2 g 4 times / day. After the acute clinical symptoms of ulcerative colitis have subsided, Sulfasalazine-EH is prescribed in a maintenance dose of 500 mg 3-4 times / day. for several months.
Children aged 5-7 years are prescribed 250-500 mg 3-6 times / day, children over 7 years old - 500 mg 3-6 times / day. Sulfasalazine-EH should be taken after meals.
Children aged 5-7 years are prescribed 250-500 mg 3-6 times / day, children over 7 years old - 500 mg 3-6 times / day. Sulfasalazine-EH should be taken after meals.
Adverse reactions
From the side of the central nervous system and peripheral nervous system: headache, dizziness, tinnitus, ataxia, convulsions, sleep disturbances, hallucinations, peripheral neuropathy.From the urinary system: renal dysfunction, interstitial nephritis.
From the digestive system: nausea, vomiting, diarrhea, abdominal pain, anorexia, hepatitis, pancreatitis.
From the respiratory system: interstitial pneumonitis and other lesions of the lung tissue.
From the hematopoietic system: anemia, leukopenia, thrombocytopenia, agranulocytosis.
On the part of the reproductive system: transient oligospermia, infertility.
Allergic reactions: skin rash, fever, anaphylactic shock.
Others: it is possible to stain yellow skin, urine, soft contact lenses.
Special instructions
The use of Sulfasalazine-EH during pregnancy is possible only for strict indications in the minimum effective dose. If the course of the disease allows, it is recommended to cancel the drug in the third trimester of pregnancy.
If necessary, the use of the drug during lactation should decide on the termination of breastfeeding.
If necessary, the use of the drug during lactation should decide on the termination of breastfeeding.
- Brand name: Sulfasalazine-EN
- Active ingredient: Sulfasalazinee
- Dosage form: pills, coated.
- Manufacturer: Krka dd Novo mesto AO
- Country of Origin: Slovenia
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