Sulfocamphocaine
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Clinical Pharmacology
Sulfocamphocaine - the combined drug, has analeptic effect. Stimulates the respiratory and vasomotor centers of the medulla oblongata. It has a direct effect on the myocardium, enhancing the metabolic processes in it, improving functions and increasing its sensitivity to sympathetic impulses. Increases the tone of peripheral blood vessels. Improves pulmonary ventilation, pulmonary blood flow.
Due to the solubility in water, the drug is rapidly absorbed by subcutaneous and intramuscular administration. Does not cause the formation of infiltrates and complications (oleomas). Perhaps intravenous administration.
Indications
- acute and chronic heart failure;
- acute and chronic respiratory failure;
- cardiogenic and anaphylactic shock.
Composition
1 ml injection solution contains:
active ingredients: sulfonic acid (in terms of anhydrous) 49.6 mg, novocaine base (procaine) 50.4 mg;
excipient: water for injection up to 1 ml.
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Dosage and Administration
Sulfocamfocaine is administered subcutaneously, intramuscularly or intravenously in a dose of 2 ml of a 10% solution (0.2 g); if necessary, the frequency of administration is up to 2-3 times per day. The maximum daily dose for adults 12 ml of 10% solution (1.2 g). In acute cases, the drug is administered intravenously (slowly streamed or drip) in a single dose of 2 ml of 10% solution.
Duration of application is set individually. In chronic respiratory and heart failure, they are injected subcutaneously or intramuscularly for 20-30 days.
Adverse reactions
When using the drug may dyspeptic disorders, allergic reactions. Perhaps a decrease in blood pressure (especially in patients with baseline hypotension).
Contraindications
Hypersensitivity to the drug components (including novocaine).
Carefully: arterial hypotension.
Drug interactions
The use of Sulfocamphocaine in combination with cardiac glycosides, steroid hormones, analgesics enhances the analeptic effect of the drug.
Pregnancy and Lactation
Due to the lack of data on the use of Sulfocamphocaine during pregnancy and during breastfeeding, its use during these periods is not recommended.
Special instructions
Care should be taken when administering the drug to patients with low blood pressure due to the possibility of the development of the hypotensive effect of novocaine, which is released in the body from Sulfocamphocaine.
- Brand name: Sulfocamphocaine
- Active ingredient: Procaine, Sulfur Camphoric Acid
- Dosage form: Injection.
- Manufacturer: Pharmstandard Ufavita
- Country of Origin: Russia