Tardyferon® [Iron sulfate]

Brand Pierre Fabre Medicament

In stock 1919 Items

Available since: 2019-09-19

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Clinical Pharmacology

Tardyferon retard compensates for iron deficiency in the body, which is necessary for the synthesis of hemoglobin.
Mukoproteoze - mucopolysaccharide, obtained from the intestinal mucosa, provides better tolerability of the drug and increases the bioavailability and gradual release of ferrous iron (Fe 2+) from the drug.
Ascorbic acid helps to improve iron absorption. After taking the drug, the absorption of iron occurs mainly in the distal small intestine. The maximum concentration of iron ion in the blood plasma is reached 7 hours after taking the drug and remains elevated during the day.
On average, 10–20% of the dose taken is absorbed. Absorption increases with decreasing iron stores in the body.

Indications

Treatment and prevention of iron deficiency caused by:
- Pregnancy.
- lactation.
- Violation of the absorption of iron from the gastrointestinal tract.
- prolonged bleeding.
- Inadequate and unbalanced nutrition.

Composition

1 tablet contains: ferrous sulfate II and a half-water 256.3 mg (corresponding to 80 mg of iron).
Excipients: mucoproteiosis, ascorbic acid, potato starch, Eudragit C, dibutylphthalate, povidone, magnesium stearate, castor oil, magnesium trisilicate.
Shell composition: talc, Eudragit E, titanium dioxide, starch, wax, paraffin, sucrose.

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Dosage and Administration

The drug is taken orally after a meal. The duration of therapy is determined by the doctor individually. Adults - 1-2 pills per day. Pregnant women (II and III trimester of pregnancy) and lactating women with a preventive purpose are advised to take 1 tablet every other day.

Contraindications

- Hypersensitivity to the drug.
- Diseases accompanied by the accumulation of iron in the body: aplastic anemia, hemolytic anemia, thalassemia, hemosiderosis, hemochromatosis.
- Violation of iron absorption: sideroachrestic anemia, lead anemia, pernicious anemia (vitamin B12 deficiency), childhood (up to 6 years).

Drug interactions

At the same time taking Tardyferon with antacid drugs, tetracycline antibiotics and penicillamine absorption of iron worsens. When ascorbic acid is taken simultaneously, iron absorption improves. It can not be prescribed together with other iron preparations, including for parenteral use, in order to avoid overdose.

Pregnancy and Lactation

Pregnant women (II and III trimester of pregnancy) and lactating women with a preventive purpose are advised to take 1 tablet every other day.

Special instructions

Before starting treatment with iron supplementation, it is necessary to make a study of the level of serum iron, serum ferritin (ie, to document iron deficiency). Drug therapy should be carried out before normalization of the blood picture (8-12 weeks). When taking the drug may be dark staining of feces, false positive benzidine test. It should be borne in mind that drinking large amounts of tea reduces the absorption of iron ions in the gastrointestinal tract. Special studies on the use of the drug in children have been conducted.

Overdosage

Symptoms: nausea, vomiting, diarrhea.
Treatment: if overdose is suspected, it is necessary to conduct a study of the content of serum iron and serum ferritin level, make a gastric lavage, put inside milk and a raw egg to enhance the binding of iron ions in the gastrointestinal tract and their subsequent excretion. In the case of a significant excess of normal serum ferritin levels, the appointment of an iron chelator (desferal) is necessary.